Πλοήγηση ανά Θέμα "COMPLEX"

Antimitochondrial antibodies of immunoglobulin G3 subclass are associated with a more severe disease course in primary biliary cirrhosis

Rigopoulou, E. I.; Davies, E. T.; Bogdanos, D. P.; Liaskos, C.; Mytilinaiou, M.; Koukoulis, G. K.; Dalekos, G. N.; Vergani, D. (2007)

Background/Aims: Primary biliary cirrhosis (PBC) is characterised by the presence of immunoglobulin (Ig) G antimitochondrial antibodies (AMA), which are routinely detected by indirect immunofluorescence (IFL) using composite ...

Arthroscopic Repair for Chronic Anterior Shoulder Instability A Comparative Study Between Patients With Bankart Lesions and Patients With Combined Bankart and Superior Labral Anterior Posterior Lesions

Hantes, M. E.; Venouziou, A. I.; Liantsis, A. K.; Dailiana, Z. H.; Malizos, K. N. (2009)

Background: Although labrum lesions in patients with chronic anterior shoulder instability may not only involve detachment of the anteroinferior labrum but a lesion of the superior glenoid labrum as well, no studies have ...

Bacterially produced human HIF-1 alpha is competent for heterodimerization and specific DNA-binding

Chachami, G.; Paraskeva, E.; Georgatsou, E.; Bonanou, S.; Simos, G. (2005)

Hypoxia-inducible factor 1α (HIF- 1α) is the regulatory Subunit of HIF- 1. the transcriptional activator and key mediator of the cellular response to hypoxia. Regulation of HIF-1α Occurs at multiple levels ...

Catch the kinase conformer

McInnes, C.; Mezna, M.; Kontopidis, G. (2006)

Protein kinases exist in inactive and active states, but little attention has been paid to which state is or should be the target in drug discovery efforts. In this issue of Chemistry & Biology, Okram et al. [1] tackle ...

A Comprehensive Phylogenetic Analysis of Deadenylases

Pavlopoulou, A.; Vlachakis, D.; Balatsos, N. A. A.; Kossida, S. (2013)

Deadenylases catalyze the shortening of the poly(A) tail at the messenger ribonucleic acid (mRNA) 3'-end in eukaryotes. Therefore, these enzymes influence mRNA decay, and constitute a major emerging group of promising ...

Conformational analysis of two novel cytotoxic C2-substituted pyrrolo 2,3-f quinolines in aqueous media, organic solvents, membrane bilayers and at the putative active site

Varvarigou, N.; Megariotis, G.; Leonis, G.; Vrontaki, E.; Maniati, A. M.; Vlachou, M.; Eikosipentaki, A.; Kompogennitaki, R.; Papadopoulos, M. G.; Grdadolnik, S. G.; Komiotis, D.; Mavromoustakos, T.; Tsotinis, A. (2012)

We have performed: (i) conformational analysis of two novel cytotoxic C2-substituted pyrrolo[2,3-f]quinolines Se and 5g in deuterated dimethylsulfoxide (DMSO-d(6)) utilizing NOE results from NMR spectroscopy; (ii) molecular ...

ENERGY LOCALIZATION FOR DILATONIC BLACK HOLE GEOMETRIES WITH A PURE MONOPOLE FIELD

Radinschi, I.; Grammenos, T. (2010)

The energy distribution of black holes with a dilaton and a pure monopole field is calculated by using Moller's energy-momentum complex. The four-dimensional space-times considered are static, spherically symmetric and ...

Epidemiology and clinical significance of mycobacterial respiratory infections in Central Greece

Gerogianni, I.; Papala, M.; Kostikas, K.; Petinaki, E.; Gourgoulianis, K. I. (2008)

SETTING: A 750-bed tertiary referral hospital in Central Greece. OBJECTIVE: To determine the incidence of non-tuberculous mycobacteria (NTM) respiratory infection based on the isolation of NTM in respiratory specimens, to ...

Epstein-Barr Virus Immortalization of Human B-Cells Leads to Stabilization of Hypoxia-Induced Factor 1 Alpha, Congruent with the Warburg Effect

Darekar, S.; Georgiou, K.; Yurchenko, M.; Yenamandra, S. P.; Chachami, G.; Simos, G.; Klein, G.; Kashuba, E. (2012)

Background: Epstein-Barr virus (EBV) encodes six nuclear transformation-associated proteins that induce extensive changes in cellular gene expression and signaling and induce B-cell transformation. The role of HIF1A in ...

A facile, one-step conversion of 6-O-trityl and 6-O-TBDMS monosaccharides into the corresponding formate esters

Komiotis, D.; Agelis, G.; Manta, S.; Tzioumaki, N.; Tsoukala, E.; Antonakis, K. (2006)

A convenient method has been developed for a facile and high-yield conversion of 6-O-tertbutyldimethylsilyl and 6-O-trityl protected monosaccharides to their formate esters, which may serve as useful intermediates for the ...

Heterogeneity testing in meta-analysis of genome searches

Zintzaras, E.; Ioannidis, J. P. A. (2005)

Genome searches for identifying susceptibility loci for the same complex disease often give inconclusive or inconsistent results. Genome Search Meta-analysis (GSMA) is an established non-parametric method to identify genetic ...

HLA-C, CSTA and DS12346 susceptibility alleles confer over 100-fold increased risk of developing psoriasis: evidence of gene interaction

Vasilopoulos, Y.; Sagoo, G. S.; Cork, M. J.; Walters, K.; Tazi-Ahnini, R. (2011)

Psoriasis is an inflammatory skin disorder that exhibits multifactorial mode of inheritance. In addition to the well-known susceptibility locus PSORS1 many other loci have been shown to be implicated in the genetic ...

Hypoxia-inducible factor-1 alpha (HIF-1 alpha) expression in placentae of women with iron deficiency anemia and beta-thalassemia trait

Michalitsi, V.; Dafopoulos, K.; Gourounti, K.; Messini, C.; Ioannou, M.; Christodoulaki, C.; Panagopoulos, P.; Messinis, I. (2015)

Objective: To investigate hypoxia-inducible factor-1 alpha (HIF-1 alpha) expression in placentae of women with iron-deficiency anemia and beta-thalassemia trait and to correlate the results with hematological parameters ...