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Auflistung Nach Schlagwort "ARTHRITIS"

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    • Arthroscopic ankle arthrodesis 

      Gougoulias, N. E.; Agathangelidis, F. G.; Parsons, S. W. (2007)
      Background: Arthroscopic arthrodesis has been used mainly for in situ fusion of arthritic ankles without deformity. This paper presents the application of arthroscopic arthrodesis of ankles with marked deformity. Methods: ...

    • The impact of frequently encountered cardiovascular risk factors on sexual dysfunction in rheumatic disorders 

      Anyfanti, P.; Pyrpasopoulou, A.; Triantafyllou, A.; Doumas, M.; Gavriilaki, E.; Triantafyllou, G.; Gkaliagkousi, E.; Chatzimichailidou, S.; Petidis, K.; Avagianou, P. A.; Zamboulis, C.; Aslanidis, S.; Douma, S. (2013)
      Traditional cardiovascular risk factors have been acknowledged as major contributors to sexual dysfunction in the general population. The purpose of this study was to explore their impact on sexual function in rheumatologic ...

    • Lipid metabolism and osteoarthritis: Lessons from atherosclerosis 

      Gkretsi, V.; Simopoulou, T.; Tsezou, A. (2011)
      Osteoarthritis (OA) is an age-related degenerative disease comprising the main reason of handicap in the Western world. Interestingly, to date, there are neither available biomarkers for early diagnosis of the disease nor ...

    • Low-Density Lipoprotein Receptor-Related Protein 5 (LRP5) Expression in Human Osteoarthritic Chondrocytes 

      Papathanasiou, I.; Malizos, K. N.; Tsezou, A. (2010)
      The aim of this study was to investigate the activation of the Wnt/beta-catenin pathway in osteoarthritis and the role of low-density lipoprotein receptor-related protein 5 (LRP5) in human osteoarthritic chondrocytes. The ...

    • Meta-analysis of association between the ASPN D-repeat and osteoarthritis 

      Nakamura, T.; Shi, D.; Tzetis, M.; Rodriguez-Lopez, J.; Miyamoto, Y.; Tsezou, A.; Gonzalez, A.; Jiang, Q.; Kamatani, N.; Loughlin, J.; Ikegawa, S. (2007)
      Osteoarthritis (OA) is the most common form of human arthritis. Genetic factors have been implicated in OA. It was reported that an aspartic acid (D)-repeat polymorphism in the gene encoding asporin (ASPN) was associated ...

    • A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip 

      Evangelou, E.; Kerkhof, H. J.; Styrkarsdottir, U.; Ntzani, E. E.; Bos, S. D.; Esko, T.; Evans, D. S.; Metrustry, S.; Panoutsopoulou, K.; Ramos, Y. F. M.; Thorleifsson, G.; Tsilidis, K. K.; Arden, N.; Aslam, N.; Bellamy, N.; Birrell, F.; Blanco, F. J.; Carr, A.; Chapman, K.; Day-Williams, A. G.; Deloukas, P.; Doherty, M.; Engstrom, G.; Helgadottir, H. T.; Hofman, A.; Ingvarsson, T.; Jonsson, H.; Keis, A.; Keurentjes, J. C.; Kloppenburg, M.; Lind, P. A.; McCaskie, A.; Martin, N. G.; Milani, L.; Montgomery, G. W.; Nelissen, Rghh; Nevitt, M. C.; Nilsson, P. M.; Ollier, W. E. R.; Parimi, N.; Rai, A.; Ralston, S. H.; Reed, M. R.; Riancho, J. A.; Rivadeneira, F.; Rodriguez-Fontenla, C.; Southam, L.; Thorsteinsdottir, U.; Tsezou, A.; Awallis, G.; Wilkinson, J. M.; Gonzalez, A.; Lane, N. E.; Lohmander, L. S.; Loughlin, J.; Metspalu, A.; Uitterlinden, A. G.; Jonsdottir, I.; Stefansson, K.; Slagboom, P. E.; Zeggini, E.; Meulenbelt, I.; Ioannidis, J. P. A.; Spector, T. D.; van Meurs, J. B. J.; Valdes, A. M.; arc, Ogen Consortium (2014)
      Objectives Osteoarthritis (OA) is the most common form of arthritis with a clear genetic component. To identify novel loci associated with hip OA we performed a meta-analysis of genome-wide association studies (GWAS) on ...

    • Optimization of TNF-alpha, overexpression in Escherichia coli using response surface methodology: Purification of the protein and oligomerization studies 

      Papaneophytou, C. P.; Kontopidis, G. A. (2012)
      Tumor necrosis factor-alpha (TNF-alpha) is responsible for many autoimmune disorders including rheumatoid arthritis, psoriasis, Chron's disease, stroke, and atherosclerosis. Thus, inhibition of TNF-alpha is a major challenge ...

    • Retinal vasculitis in rheumatic diseases: an unseen burden 

      Androudi, S.; Dastiridou, A.; Symeonidis, C.; Kump, L.; Praidou, A.; Brazitikos, P.; Kurup, S. K. (2013)
      Retinal vascular inflammation, a potentially blinding condition (herein: retinal vasculitis (RV)) is commonly associated with a heterogeneous group of diseases characterized by systemic inflammatory cell infiltration and/or ...

    • Secukinumab in the Treatment of Noninfectious Uveitis: Results of Three Randomized, Controlled Clinical Trials 

      Dick, A. D.; Tugal-Tutkun, I.; Foster, S.; Zierhut, M.; Liew, S. H. M.; Bezlyak, V.; Androudi, S. (2013)
      Purpose: To determine the efficacy and safety of different doses of secukinumab, a fully human monoclonal antibody for targeted interleukin-17A blockade, in patients with noninfectious uveitis. Design: Three multicenter, ...