Πλοήγηση ανά Θέμα "ANTITUMOR-ACTIVITY"
Αποτελέσματα 1-3 από 3
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Dideoxy fluoro-ketopyranosyl nucleosides as potent antiviral agents: Synthesis and biological evaluation of 2,3-and 3,4-dideoxy-3-fluoro-4-and-2-keto-beta-D-glucopyranosyl derivatives of N-4-benzoyl cytosine
(2009)The synthesis of the dideoxy fluoro ketopyramonucleoside analogues, 1-(2,3-dideoxy-3-fluoro-6-O-trityl-beta-D-glycero-hexopyranosyl-4-ulose)-N-4-benzoyl cytosine (7a), 1-(3,4-dideoxy-3-fluoro-6-O-trityl-beta-D-glycero-he ... -
Fluoro-ketopyranosyl nucleosides: Synthesis and biological evaluation of 3-fluoro-2-keto-beta-D-glucopyranosyl derivatives of N-4-benzoyl cytosine
(2007)1,2:5,6-Di-O-isopropylidene-ot-D-glucofuranose on mild oxidation, reduction, fluorination, and deisopropylidenation followed by acetylation gave peracetylated 3-deoxy-3-fluoro-D-glueopyranose. This was coupled with silylated ... -
Unsaturated fluoro-ketopyranosyl nucleosides: Synthesis and biological evaluation of 3-fluoro-4-keto-beta-D-glucopyranosyl derivatives of N(4)-benzoyl cytosine and N(6)-benzoyl adenine
(2008)The protected beta-nucleosides 1-(2,4,6-tri-O-acetyl-3-deoxy-3-fluoro-beta-D-glucopyranosyl)-N(4)-benzoyl cytosine (2a) and 9-(2,4,6-tri-O-acetyl3-deoxy-3-fluoro-O-D-glucopyranosyl)-N6-benzoyl adenine (2b), were synthesized ...