Listar por autor "Stamatopoulos, K."
Mostrando ítems 1-11 de 11
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Analysis of transferrin receptor-1 and-2 expression in B cell chronic lymphocytic leukemia (B-CLL)
Kollia, P.; Smilevska, T.; Stamatopoulos, K.; Tsompanakou, A.; Stavroyianni, N.; Samara, M.; Paterakis, G.; Douka, V.; Hatzidimitriou, A.; Tachynopoulou, V.; Fassas, A.; Anagnostopoulos, A. (2003) -
Clinical, immunophenotypic, and molecular profiling of trisomy 12 in chronic lymphocytic leukemia and comparison with other karyotypic subgroups defined by cytogenetic analysis
Athanasiadou, A.; Stamatopoulos, K.; Tsompanakou, A.; Gaitatzi, M.; Kalogiannidis, P.; Anagnostopoulos, A.; Fassas, A.; Tsezou, A. (2006)In a cohort of 130 unselected chronic lymphocytic leukemia (CLL) patients, 73 cases had normal karyotypes, 57 cases had abnormal karyotypes, and 22/57 cases carried more than one abnormality. Trisomy 12 (+ 12) was the most ... -
Differential impact of transcriptional vs. post-transcriptional control mechanisms in the regulation of transferrin receptor-1 and-2 in human myeloid cells
Samara, M.; Chiotoglou, I.; Chassanidis, C.; Likousi, S.; Stamatopoulos, K.; Kollia, P. (2006) -
Evidence for differential regulation of transferrin receptor 1 in normal vs. malignant B cells
Chiotoglou, I.; Smilevska, T.; Stamatopoulos, K.; Samara, M.; Likousi, S.; Belessi, C.; Laoutaris, N.; Fassas, A.; Stathakis, N.; Kollia, P. (2005) -
Immunoglobulin genes in multiple myeloma: Expressed and non-expressed repertoires, heavy and light chain pairings and somatic mutation patterns in a series of 101 cases
Hadzidimitriou, A.; Stamatopoulos, K.; Belessi, C.; Lalayianni, C.; Stavroyianni, N.; Smilevska, T.; Hatzi, K.; Laoutaris, N.; Anagnostopoulos, A.; Kollia, P.; Fassas, A. (2006)Background and Objectives. The available data on the immunoglobulin gene (IG) repertoire in multiple myeloma (MM) derive mainly from heavy chains; considerably less is known about light chains. We assessed in parallel IGH ... -
Molecular analysis of transferrin receptor mRNA expression in acute myeloid leukaemia
Kollia, P.; Stavroyianni, N.; Stamatopoulos, K.; Zoi, K.; Viniou, N.; Mantzourani, M.; Noguchi, C. T.; Paterakis, G.; Abazis, D.; Pangalos, C.; Loukopoulos, D.; Yataganas, X. (2001)Transferrin receptor (TfR, CD71) is an integral membrane glycoprotein that mediates cellular uptake of iron. In most tissues, TfR expression is correlated positively with proliferation and regulated at the post-transcriptional ... -
Molecular evidence for transferrin receptor 2 expression in all FAB subtypes of acute myeloid leukemia
Kollia, P.; Samara, M.; Stamatopoulos, K.; Belessi, C.; Stavroyianni, N.; Tsompanakou, A.; Athanasiadou, A.; Vainvakopoulos, N.; Laoutaris, N.; Anagnostopoulos, A.; Fassas, A. (2003)We examined transferrin receptor (TfR) 1 and TfR2 mRNA expression in 50 acute myeloid leukemia (AML) patients by RT-PCR, with primers specific for exons 15-17 (TfR1), 3-5 (TfR2-alpha) and 4-5 (TfR2-beta) of the corresponding ... -
Predominantly post-transcriptional regulation of activation molecules in chronic lymphocytic leukemia: The case of transferrin receptors
Chiotoglou, I.; Smilevska, T.; Samara, M.; Likousi, S.; Belessi, C.; Athanasiadou, I.; Stavroyianni, N.; Samara, S.; Laoutaris, N.; Vamvakopoulos, N.; Anagnostopoulos, A.; Fassas, A.; Stamatopoulos, K.; Kollia, P. (2008)Transcriptional and post-transcriptional control mechanisms have a differential impact on cellular physiology depending on activation status. Several lines of evidence suggest that chronic lymphocytic leukemia (CLL) malignant ... -
Report of novel chromosomal abnormalities in a series of 130 chronic lymphocytic leukemia patients studied by classic cytogenetic analysis
Athanasiadou, A.; Stamatopoulos, K.; Tsezou, A.; Vadikolia, C.; Asteriou, O.; Fassas, A.; Anagnostopoulos, A. (2006)One-hundred-and-thirty typical, unselected CLL cases were studied by conventional cytogenetic analysis. Seventy-three patients (56.2%) had normal karyotype ('normal sub-group'), while 57/130 patients (43.8%) had abnormal ... -
Report of two novel chromosomal translocations in chronic lymphocytic leukemia
Athanasiadou, A.; Stamatopoulos, K.; Tsompanakou, A.; Foutsitsakis, D.; Fassas, A.; Anagnostopoulos, A.; Tsezou, A. (2005)Two novel chromosomal translocations were identified in 2 patients with chronic lymphocytic leukemia (CLL). Case 1: 60 year-old male, stage Rai 0/Binet A, with mutated immunoglobulin heavy (IgH) and lambda (Iglambda) light ... -
Transferrin receptor-1 and 2 expression in chronic lymphocytic leukemia
Smilevska, T.; Stamatopoulos, K.; Samara, M.; Belessi, C.; Tsompanakou, A.; Paterakis, G.; Stavroyianni, N.; Athanasiadou, I.; Chiotoglou, I.; Hadzidimitriou, A.; Athanasiadou, A.; Douka, V.; Saloum, R.; Laoutaris, N.; Anagnostopoulos, A.; Fassas, A.; Stathakis, N.; Kollia, P. (2006)Transferrin receptor (TfR)-1 and 2 mRNA and CD71 (TfR1) expression was analyzed in 118 CLL patients. Ninety-five out of 109 analyzed cases expressed CD71, mostly at a high level; 60% of CD71 (+) cases were IGH-mutated. All ...