Parcourir par auteur "Mytilinaiou, M. G."
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ANA IMMUNOFLUORESCENCE PATTERNS AND THEIR ASSOCIATION WITH REACTIVITY TO MOLECULARLY DEFINED NUCLEAR TARGETS IN CHILDREN WITH TYPE 1 AUTOIMMUNE HEPATITIS
Mytilinaiou, M. G.; Teegen, B.; Grammatikopoulos, A.; Davies, E.; Rigopoulou, E. I.; Komorowski, L.; Dahnrich, C.; Mieli-Vergani, G.; Fechner, K.; Vergani, D.; Bogdanos, D. P. (2011) -
ANTI-ASIALOGLYCOPROTEIN RECEPTOR ANTIBODY MEASURED BY ELISA IS A SPECIFIC MARKER OF LIVER AUTOIMMUNITY AND MIRRORS DISEASE ACTIVITY IN PATIENTS WITH AUTOIMMUNE HEPATITIS
Mytilinaiou, M. G.; Roggenbuck, D.; Grammatikopoulos, A.; Davies, E.; Romanidou, O.; Rigopoulou, E. I.; Mieli-Vergani, G.; Vergani, D.; Bogdanos, D. P. (2011) -
Asialoglycoprotein receptor (ASGPR) as target autoantigen in liver autoimmunity: Lost and found
Rigopoulou, E. I.; Roggenbuck, D.; Smyk, D. S.; Liaskos, C.; Mytilinaiou, M. G.; Feist, E.; Conrad, K.; Bogdanos, D. P. (2012)Asialoglycoprotein receptor (ASGPR) has attracted the attention of liver immunologists for many years. This liver-specific lectin was found to be a major B and T cell autoantigenic target in patients with autoimmune liver ... -
Autoantibodies to asialoglycoprotein receptor (ASGPR) in patients with autoimmune liver diseases
Villalta, D.; Mytilinaiou, M. G.; Elsner, M.; Hentschel, C.; Cuccato, J.; Somma, V.; Schierack, P.; Roggenbuck, D.; Bogdanos, D. P. (2015)Background: The liver asialoglycoprotein receptor (ASGPR) is the only organ-specific autoantigenic target in autoimmune hepatitis (AIH) patients and corresponding autoantibodies (Abs) have been suggested aiding in the ... -
Bioinformatic and immunological analysis reveals lack of support for measles virus related mimicry in Crohn's disease
Polymeros, D.; Tsiamoulos, Z. P.; Koutsoumpas, A. L.; Smyk, D. S.; Mytilinaiou, M. G.; Triantafyllou, K.; Bogdanos, D. P.; Ladas, S. D. (2014)Background: A link between measles virus and Crohn's disease (CD) has been postulated. We assessed through bioinformatic and immunological approaches whether measles is implicated in CD induction, through molecular mimicry. ... -
DIAGNOSTIC AND CLINICAL SIGNIFICANCE OF ANTI-RO52 ANTIBODIES IN 609 CASES WITH PRIMARY BILIARY CIRRHOSIS FROM UK, SPAIN AND GREECE
Mytilinaiou, M. G.; Pares, A.; Spyrou, E. S.; Rigopoulou, E. I.; Dalekos, G. N.; Vergani, D.; Bogdanos, D. P. (2009) -
Diagnostic and clinical utility of antibodies against the nuclear body promyelocytic leukaemia and Sp100 antigens in patients with primary biliary cirrhosis
Mytilinaiou, M. G.; Meyer, W.; Scheper, T.; Rigopoulou, E. I.; Probst, C.; Koutsoumpas, A. L.; Abeles, D.; Burroughs, A. K.; Komorowski, L.; Vergani, D.; Bogdanos, D. P. (2012)Background: The lack of an immunoassay that detects antibodies to promyelocytic leukaemia (PML) protein, the primary biliary cirrhosis (PBC)-specific multiple nuclear dot (MND) antigen, has prompted us to develop a line ... -
F1F0-ATPASE AS AN AUTOANTIGENIC TARGET IN PATIENTS WITH ANTI-MITOCHONDRIAL ANTIBODY NEGATIVE PRIMARY BILIARY CIRRHOSIS
Mytilinaiou, M. G.; Komorowski, L.; Rigopoulou, E. I.; Janssen, A.; Probst, C.; Vergani, D.; Bogdanos, D. P. (2010) -
Familial primary biliary cirrhosis: Like mother, like daughter?
Smyk, D. S.; Rigopoulou, E. I.; Pares, A.; Mytilinaiou, M. G.; Invernizzi, P.; Bogdanos, D. P. (2012)The reasons underlying why autoimmune diseases overwhelmingly affect women more than men are not clear. Nor are the reasons why autoimmune disease is more prevalent in families. This review uses primary biliary cirrhosis ... -
Helicobacter pylori and autoimmune disease: Cause or bystander
Smyk, D. S.; Koutsoumpas, A. L.; Mytilinaiou, M. G.; Rigopoulou, E. I.; Sakkas, L. I.; Bogdanos, D. P. (2014)Helicobacter pylori (H. pylori) is the main cause of chronic gastritis and a major risk factor for gastric cancer. This pathogen has also been considered a potential trigger of gastric autoimmunity, and in particular of ... -
Ileal InflammationMay Trigger the Development of GP2-Specific Pancreatic Autoantibodies in Patients with Crohn's Disease
Pavlidis, P.; Romanidou, O.; Roggenbuck, D.; Mytilinaiou, M. G.; Al-Sulttan, F.; Liaskos, C.; Smyk, D. S.; Koutsoumpas, A. L.; Rigopoulou, E. I.; Conrad, K.; Forbes, A.; Bogdanos, D. P. (2012)Why zymogen glycoprotein 2 (GP2), the Crohn's disease (CD)-specific pancreatic autoantigen, is the major target of humoral autoimmunity in inflammatory bowel diseases (IBD) is uknown. Recent evidence demonstrates that GP2 ... -
New sensitive technique for the detection of anti-smooth muscle antibodies in autoimmune hepatitis
Liaskos, C.; Mytilinaiou, M. G.; Grammatikopoulos, A.; Smyk, D. S.; Orfanidou, T.; Mavropoulos, A.; Norman, G. L.; Rigopoulou, E. I.; Mieli-Vergani, G.; Bogdanos, D. P.; Vergani, D. (2012) -
PBC triggers in water reservoirs, coal mining areas and waste disposal sites: From Newcastle to New York
Smyk, D.; Mytilinaiou, M. G.; Rigopoulou, E. I.; Bogdanos, D. P. (2010)Various environmental factors have been proposed as triggers of primary biliary cirrhosis (PBC), a progressive autoimmune cholestatic liver disease which is characterised by the destruction of the small intrahepatic bile ... -
Primary biliary cirrhosis associated with systemic sclerosis: Diagnostic and clinical challenges
Rigamonti, C.; Bogdanos, D. P.; Mytilinaiou, M. G.; Smyk, D. S.; Rigopoulou, E. I.; Burroughs, A. K. (2011)Patients with primary biliary cirrhosis (PBC) often have concurrent limited systemic sclerosis (SSc). Conversely, up to one-fourth of SSc patients are positive for PBC-specific antimitochondrial antibodies (AMA). The ... -
Primary Biliary Cirrhosis-Specific Antimitochondrial Antibodies in Neonatal Haemochromatosis
Smyk, D.; Mytilinaiou, M. G.; Grammatikopoulos, T.; Knisely, A. S.; Mieli-Vergani, G.; Bogdanos, D. P.; Vergani, D. (2013)Background and Aim. Neonatal hemochromatosis (NH) is characterised by severe liver injury and extrahepatic siderosis sparing the reticuloendothelial system. Its aetiology is obscure, although it has been proposed as an ... -
THE ROLE OF HERPES SIMPLEX VIRUS TYPE 1 IN THE INDUCTION OF PROMYEOLOCYTIC LEUKAEMIA SPECIFIC RESPONSES IN PRIMARY BILIARY CIRRHOSIS
Pavlidis, P.; Mytilinaiou, M. G.; Koutsoumpas, A.; Rigopoulou, E. I.; Vergani, D.; Bogdanos, D. P. (2009) -
Towards systemic sclerosis and away from primary biliary cirrhosis: The case of PTPN22
Smyk, D. S.; Mytilinaiou, M. G.; Milkiewicz, P.; Rigopoulou, E. I.; Invernizzi, P.; Bogdanos, D. P. (2012)Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease characterized by immune-mediated destruction of the small and medium size intrahepatic bile ducts. PBC patients often have concomitant autoimmune ... -
Twin studies in autoimmune disease: Genetics, gender and environment
Bogdanos, D. P.; Smyk, D. S.; Rigopoulou, E. I.; Mytilinaiou, M. G.; Heneghan, M. A.; Selmi, C.; Gershwin, M. E. (2012)Twin studies are powerful tools to discriminate whether a complex disease is due to genetic or environmental factors. High concordance rates among monozygotic (MZ) twins support genetic factors being predominantly involved, ...