Πλοήγηση ανά Συγγραφέα "Gortsilas, P."
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Multiplex PCR assay for the rapid identification of human papillomavirus genotypes 16, 18, 45, 35, 66, 33, 51, 58, and 31 in clinical samples
Tsakogiannis, D.; Diamantidou, V.; Toska, E.; Kyriakopoulou, Z.; Dimitriou, T. G.; Ruether, I. G.; Gortsilas, P.; Markoulatos, P. (2015)The causal association between persistent human papillomavirus (HPV) infection and cervical cancer has lead to the development of a variety of molecular assays for HPV detection. The present study focused on the development ... -
Nucleotide polymorphisms of the human papillomavirus 16 E1 gene
Tsakogiannis, D.; Darmis, F.; Gortsilas, P.; Ruether, I. G. A.; Kyriakopoulou, Z.; Dimitriou, T. G.; Amoutzias, G.; Markoulatos, P. (2014)The E1 ORF is one of the most conserved regions in the human papillomavirus (HPV) genome. The complete E1 gene of the HPV16 genome was amplified with four overlapping primer sets in 16 high-grade (CIN II, III) and 13 ... -
Sites of disruption within E1 and E2 genes of HPV16 and association with cervical dysplasia
Tsakogiannis, D.; Gortsilas, P.; Kyriakopoulou, Z.; Ruether, I. G. A.; Dimitriou, T. G.; Orfanoudakis, G.; Markoulatos, P. (2015)Integration of HPV16 DNA into the host chromosome usually disrupts the E1 and/or E2 genes. The present study investigated the disruption of E1, E2 genes in a total of eighty four HPV16-positive precancerous and cervical ...