Sfoglia per Autore "Chassanidis, C."
Items 1-12 di 12
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The 5′ regulatory region of the human fetal globin genes is a gene conversion hotspot
Kalamaras, A.; Chassanidis, C.; Samara, M.; Chiotoglou, I.; Vamvakopoulos, N. K.; Papadakis, M. N.; Kollia, P.; Patrinos, G. P. (2008)The human fetal globin genes consist of the first mammalian genomic loci for which gene conversion was reported. To date, 14 gene conversions have been described in the human Gγ- and Aγ-globin genes, the vast majority of ... -
Bone morphogenetic proteins (BMPs) expression in the femoral heads of patients with avascular necrosis
Samara, S.; Dailiana, Z.; Varitimidis, S.; Chassanidis, C.; Koromila, T.; Malizos, K. N.; Kollia, P. (2013)Avascular necrosis (AVN) is a disorder of the bone repair process which usually results in femoral head (FH) destruction. Bone morphogenetic proteins (BMPs) are the key proteins regulating bone remodelling and healing. ... -
CER1 gene variations associated with bone mineral density, bone markers, and early menopause in postmenopausal women
Koromila, T.; Georgoulias, P.; Dailiana, Z.; Ntzani, E. E.; Samara, S.; Chassanidis, C.; Aleporou-Marinou, V.; Kollia, P. (2013)Background: Osteoporosis has a multifactorial pathogenesis characterized by a combination of low bone mass and increased fragility. In our study, we focused on the effects of polymorphisms in CER1 and DKK1 genes, recently ... -
Compound heterozygosity for the Cretan type of non-deletional hereditary persistence of fetal hemoglobin and beta-thalassemia or Hb Sabine confirms the functional role of the A gamma-158 C > T mutation in gamma-globin gene transcription
Kollia, P.; Kalamaras, A.; Chassanidis, C.; Samara, M.; Vamvakopoulos, N. K.; Radmilovic, M.; Pavlovic, S.; Papadakis, M. N.; Patrinos, G. P. (2008) -
Compound heterozygosity of non-deletional hereditary persistence of fetal hemoglobin and delta beta-thalassemia
Kalamaras, A.; Chassanidis, C.; Samara, M.; Papadakis, M. N.; Vagena, A.; Aleporou-Marinou, V.; Patrinos, G. P.; Kollia, P. (2008) -
Differential impact of transcriptional vs. post-transcriptional control mechanisms in the regulation of transferrin receptor-1 and-2 in human myeloid cells
Samara, M.; Chiotoglou, I.; Chassanidis, C.; Likousi, S.; Stamatopoulos, K.; Kollia, P. (2006) -
Expression profile of osteoprotegerin, RANK and RANKL genes in the femoral head of patients with avascular necrosis
Samara, S.; Dailiana, Z.; Chassanidis, C.; Koromila, T.; Papatheodorou, L.; Malizos, K. N.; Kollia, P. (2014)Introduction: Femoral head avascular necrosis (AVN) is a recalcitrant disease of the hip that leads to joint destruction. Osteoprotegerin (OPG), Receptor Activator of Nuclear Factor kappa-B (RANK) and RANK ligand (RANKL) ... -
The Hellenic type of nondeletional hereditary persistence of fetal hemoglobin results from a novel mutation (g.-109G > T) in the HBG2 gene promoter
Chassanidis, C.; Kalamaras, A.; Phylactides, M.; Pourfarzad, F.; Likousi, S.; Maroulis, V.; Papadakis, M. N.; Vamvakopoulos, N. K.; Aleporou-Marinou, V.; Patrinos, G. P.; Kollia, P. (2009)Nondeletional hereditary persistence of fetal hemoglobin (nd-HPFH), a rare hereditary condition resulting in elevated levels of fetal hemoglobin (Hb F) in adults, is associated with promoter mutations in the human fetal ... -
Induction of fetal hemoglobin (HbF) by novel alkylating agents in human erythroid cells; synergistic effects with established HbF-inducing agents
Chiotoglou, I.; Samara, M.; Likousi, S.; Samara, S.; Chassanidis, C.; Iakovidou, Z.; Mioglou, E.; Mourelatos, D.; Papadakis, M.; Liakos, P.; Kollia, P. (2008) -
Large-scale population genetic analysis for hemoglobinopathies reveals different mutation spectra in central Greece compared to the rest of the country
Samara, M.; Chiotoglou, I.; Kalamaras, A.; Likousi, S.; Chassanidis, C.; Vagena, A.; Vagenas, C.; Eftichiadis, E.; Vamvakopoulos, N.; Patrinos, G. P.; Kollia, P. (2007)We have undertaken a large population screening study to identify the molecular basis of hemoglobinopathies in the central Greece region. A total of 845 unrelated beta-thalassemia patients and alpha-, beta-, and delta ... -
Novel Sequence Variations in the CER1 Gene Are Strongly Associated with Low Bone Mineral Density and Risk of Osteoporotic Fracture in Postmenopausal Women
Koromila, T.; Dailiana, Z.; Samara, S.; Chassanidis, C.; Tzavara, C.; Patrinos, G. P.; Aleporou-Marinou, V.; Kollia, P. (2012)Osteoporosis is a common skeletal disease characterized by a combination of low bone mass and increased fragility. In this case-control study, we investigated the possible association of two novel candidate genes, CER1 and ... -
Predictive role of cytokine gene polymorphisms for the development of femoral head osteonecrosis
Samara, S.; Kollia, P.; Dailiana, Z.; Chassanidis, C.; Papatheodorou, L.; Koromila, T.; Malizos, K. N. (2012)Introduction: Osteonecrosis (ON) is a multifactorial disease that leads to hip destruction. Lately, much focus has been at femoral head preservation with nonsurgical methods. In this study we examined the polymorphisms of ...