Πλοήγηση ανά Συγγραφέα "Aligiannis, N."
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Antioxidant and chemopreventive properties of polyphenolic compounds derived from Greek legume plant extracts
Spanou, C.; Bourou, G.; Dervishi, A.; Aligiannis, N.; Angelis, A.; Komiotis, D.; Skaltsounis, A. L.; Kouretas, D. (2008)Recently, phytochemical compounds present in legumes have gained a lot of interest because they are considered to be possible chemopreventive agents. In the present study, 14 polyphenolic compounds were extracted and ... -
Antioxidant and chemopreventive properties of Vicia faba extract and its flavonoid fractions
Spanou, C.; Aligiannis, N.; Skaltsounis, A. L.; Kouretas, D. (2008) -
The Antioxidant Effects of a Polyphenol-Rich Grape Pomace Extract In Vitro Do Not Correspond In Vivo Using Exercise as an Oxidant Stimulus
Veskoukis, A. S.; Kyparos, A.; Nikolaidis, M. G.; Stagos, D.; Aligiannis, N.; Halabalaki, M.; Chronis, K.; Goutzourelas, N.; Skaltsounis, L.; Kouretas, D. (2012)Fruits, such as grapes, are essential food of the Mediterranean diet. Grape extracts have potent antioxidant and chemopreventive properties in vitro. Numerous studies have examined the effects of plant extract administration ... -
Assessment of antioxidant activity of extracts from unique Greek varieties of Leguminosae plants using in vitro assays
Spanou, C.; Stagos, D.; Tousias, L.; Angelis, A.; Aligiannis, N.; Skaltsounis, A. L.; Kouretas, D. (2007)Background: It is believed that legumes are a very good source of micronutrients and phytochemicals that present chemopreventive activity against diseases such as diabetes, coronary heart disease and colon cancer. Methanolic ... -
Catalytic Inhibition of Eukaryotic Topoisomerases I and II by Flavonol Glycosides Extracted from Vicia faba and Lotus edulis
Tselepi, M.; Papachristou, E.; Emmanouilidi, A.; Angelis, A.; Aligiannis, N.; Skaltsounis, A. L.; Kouretas, D.; Liadaki, K. (2011)Topoisomerases are essential enzymes involved in all processes of DNA metabolism, and their inhibitors have been identified as potential anticancer agents. The present study examined the effect of nine polyphenolic compounds ... -
Chemical profile characterization of biologically active extracts obtained from Salvia species
Chaita, E.; Aligiannis, N.; Kouretas, D.; Skaltsounis, A. L. (2009) -
Correlation of total polyphenolic content with antioxidant and antibacterial activity of 24 extracts from Greek domestic Lamiaceae species
Stagos, D.; Portesis, N.; Spanou, C.; Mossialos, D.; Aligiannis, N.; Chaita, E.; Panagoulis, C.; Reri, E.; Skaltsounis, L.; Tsatsakis, A. M.; Kouretas, D. (2012)Lamiaceae family species are considered important because of their use in folk medicine, culinary and flavouring throughout the world. Their interesting bioactivities are attributed mainly to essential oils, polyphenols ... -
Effect of Leguminosae family plant extracts and polyphenolic fractions on topoisomerase I-induced nicking of DNA
Spanou, C.; Aligiannis, N.; Skaltsounis, A. L.; Kouretas, D. (2008)Topoisomerase I constitutes one of the enzymes playing crucial role in replication, transcription, recombination, chromosome condensation and maintenance of genome stability. Because it is an essential enzyme for vital ... -
Effects of Greek legume plant extracts on xanthine oxidase, catalase and superoxide dismutase activities
Spanou, C. I.; Veskoukis, A. S.; Stagos, D.; Liadaki, K.; Aligiannis, N.; Angelis, A.; Skaltsounis, A. L.; Anastasiadi, M.; Haroutounian, S. A.; Kouretas, D. (2012)Legumes are considered to have beneficial health implications, which have been attributed to their phytochemical content. Polyphenols are considered the most important phytochemical compounds extensively studied for their ... -
Effects of polyphenolic grape extract on the oxidative status of muscle and endothelial cells
Goutzourelas, N.; Stagos, D.; Demertzis, N.; Mavridou, P.; Karterolioti, H.; Georgadakis, S.; Kerasioti, E.; Aligiannis, N.; Skaltsounis, L.; Statiri, A.; Tsioutsiouliti, A.; Tsatsakis, A. M.; Hayes, A. W.; Kouretas, D. (2014)A grape pomace extract enhanced antioxidant mechanisms in muscle and endothelial cells both in the absence and in the presence of oxidative stress-induced agent tert-butyl hydroperoxide (tBHP). In particular, muscle (C2C12) ... -
Flavonoid Glycosides Isolated from Unique Legume Plant Extracts as Novel Inhibitors of Xanthine Oxidase
Spanou, C.; Veskoukis, A. S.; Kerasioti, T.; Kontou, M.; Angelis, A.; Aligiannis, N.; Skaltsounis, A. L.; Kouretas, D. (2012)Legumes and the polyphenolic compounds present in them have gained a lot of interest due to their beneficial health implications. Dietary polyphenolic compounds, especially flavonoids, exert antioxidant properties and are ... -
Grape pomace extract exerts antioxidant effects through an increase in GCS levels and GST activity in muscle and endothelial cells
Goutzourelas, N.; Stagos, D.; Housmekeridou, A.; Karapouliou, C.; Kerasioti, E.; Aligiannis, N.; Skaltsounis, A. L.; Spandidos, D. A.; Tsatsakis, A. M.; Kouretas, D. (2015)In a previous study, we demonstrated that a grape pomace extract (GPE) exerted antioxidant activity in endothelial (EA. hy926) and muscle (C2C12) cells through an increase in glutathione (GSH) levels. In the present study, ... -
Influence of Potent Antioxidant Leguminosae Family Plant Extracts on Growth and Antioxidant Defense System of Hep2 Cancer Cell Line
Spanou, C.; Stagos, D.; Aligiannis, N.; Kouretas, D. (2010)Legumes are considered to be a very good source of polyphenolic compounds that may act as chemopreventive agents, especially by their antioxidant properties. However, many of the chemopreventive properties may depend on ... -
Isolation of Lotus edulis bioactive flavonoids (Leguminosae) by Centrifugal Partition Chromatography
Angelis, A.; Spanou, C.; Aligiannis, N.; Kouretas, D.; Skaltsounis, A. L. (2009)