Sfoglia per Soggetto "pyruvate dehydrogenase complex"
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Infectious triggers of primary biliary cirrhosis: Do we know enough?
(2011)Primary biliary cirrhosis (PBC) is an immune mediated liver disease directed against the biliary epithelial cells of the small bile ducts. The disease is characterised by circulating antimitochondrial antibodies (AMA), as ... -
Popular and unpopular infectious agents linked to primary biliary cirrhosis
(2012)Primary biliary cirrhosis (PBC) is a progressive cholestatic liver disease characterized by the autoimmune destruction of the biliary epithelial cells of the small and medium-size bile ducts. The disease affects middle ... -
Primary biliary cirrhosis is characterized by IgG3 antibodies cross-reactive with the major mitochondrial autoepitope and its lactobacillus mimic
(2005)The serological hallmark of primary biliary cirrhosis (PBC) is the presence of pyruvate dehydrogenase complex E2 subunit (PDC-E2) antimitochondrial antibodies (AMAs). Anti-PDC-E2 antibodies cross-react specifically with ... -
Proteomic analysis of the mitochondrial glucocorticoid receptor interacting proteins reveals pyruvate dehydrogenase and mitochondrial 60 kDa heat shock protein as potent binding partners
(2022)Glucocorticoids are steroid hormones that regulate plethora biological actions such as growth and metabolism, immune response, and apoptosis. Glucocorticoids actions are mediated via glucocorticoid receptors which act ...