Sfoglia per Soggetto "knee osteoarthritis"
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An 11- to 15-year clinical outcome study of the Advance Medial Pivot total knee arthroplasty: Pivot knee arthroplasty
(2016)Aims The Advance Medial-Pivot total knee arthroplasty (TKA) was designed to reflect contemporary data regarding the kinematics of the knee. We wished to examine the longterm results obtained with this prosthesis by extending ... -
A 9-Year Outcome Study Comparing Cancellous Titanium-Coated Cementless to Cemented Tibial Components of a Single Knee Arthroplasty Design
(2018)Background: The cemented Advance Medial-Pivot total knee arthroplasty (TKA) was designed to reflect contemporary knee kinematics data and has shown satisfactory long-term outcomes. Methods: We retrospectively evaluated ... -
Absence of linkage to chromosomes 6q and 16p in a Greek population with knee osteoarthritis
(2006)Osteoarthritis (OA) is a common age-related debilitating disease of the joints characterized by degeneration of the articular cartilage which leads to joint pain, discomfort, and immobility. Several risk factors have been ... -
Association of KLOTHO Gene Polymorphisms with Knee Osteoarthritis in Greek Population
(2008)Based on the fact that klotho-deficient mice exhibit multiple aging phenotypes, including osteopenia and subchondral sclerosis of joints and on the recent observation that KLOTHO gene plays an important role in calcium/phosphate ... -
Association of repeat polymorphisms in the estrogen receptors alpha, beta, and androgen receptor genes with knee osteoarthritis
(2005)Genetic factors have been shown to play an important role in the etiology of osteoarthritis (OA). To elucidate the possible role of genetic variation in the estrogen receptors alpha and beta (ER-alpha, ER-beta) and androgen ... -
Association of the leptin gene with knee osteoarthritis susceptibility in a Han Chinese population: A case-control study
(2010)Previous studies have suggested that leptin works as a key regulator in the pathogenesis of osteoarthritis (OA), and genetic factors modulate OA. This study assessed the contribution of leptin gene (LEP) polymorphism(s) ... -
Comparative proteomic analysis of hypertrophic chondrocytes in osteoarthritis
(2015)Background: Osteoarthritis (OA) is a multi-factorial disease leading progressively to loss of articular cartilage and subsequently to loss of joint function. While hypertrophy of chondrocytes is a physiological process ... -
Complicated septic arthritis after knee arthroscopy in a 75-year-old man with osteoarthritis and a popliteal cyst
(2015)A 75-year-old man presented in shock secondary to septic arthritis of the knee. The patient, with a known history of knee osteoarthritis, was treated elsewhere for mechanical locking symptoms and effusion with arthroscopic ... -
Differential expression of leptin and leptin's receptor isoform (Ob-Rb) mRNA between advanced and minimally affected osteoarthritic cartilage; effect on cartilage metabolism
(2007)Objective: To investigate leptin's effect on cartilage metabolism and the pathophysiology of osteoarthritis (OA). Methods: Messenger RNA (mRNA) expression and protein levels of leptin and leptin's receptor isoforms were ... -
Differentiation between subchondral insufficiency fractures and advanced osteoarthritis of the knee using transfer learning and an ensemble of convolutional neural networks
(2022)Purpose: Subchondral insufficiency fractures (SIF) and advanced osteoarthritis (OA) of the knee are usually seen in conjunction with bone marrow lesions (BMLs) and their differentiation may pose a significant diagnostic ... -
Evaluating the “Patella-Friendly” Concept in Total Knee Arthroplasty: A Minimum 15-Year Follow-Up Outcome Study Comparing Constant Radius, Multiradius Cruciate-Retaining, and Nonanatomical Cruciate-Retaining Implants
(2021)Background: Patella-friendly femoral components were developed in order to reduce anterior knee pain and patellofemoral complications in total knee arthroplasty (TKA), but their effect on long-term outcome is still unclear. ... -
Exercise intervention on cardiorespiratory fitness in rheumatoid arthritis patients with high cardiovascular disease risk: a single-arm pilot study
(2022)Objective: In patients with rheumatoid arthritis (RA) with cardiovascular disease risk, it is unknown whether exercises are safe, improve cardiorespiratory fitness and reduce disease-related symptoms and cardiovascular-disease ... -
Explainable machine learning for knee osteoarthritis diagnosis based on a novel fuzzy feature selection methodology
(2022)Knee Osteoarthritis (ΚΟΑ) is a degenerative joint disease of the knee that results from the progressive loss of cartilage. Due to KOA’s multifactorial nature and the poor understanding of its pathophysiology, there is a ... -
Genesis 1 posterior cruciate-retaining total knee arthroplasty with asymmetric tibial tray: An 18-to-26-year long-term clinical outcome study
(2019)Background: To present the long-term clinical and radiological outcomes of the Genesis I posterior cruciate-retaining total knee arthroplasty (TKA) (Smith & Nephew Orthopaedics, Memphis, TN, USA) (one of the first designed ... -
A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22
(2010)Objective. To identify novel genes involved in osteoarthritis (OA), by means of a genome-wide association study. Methods. We tested 500,510 single-nucleotide polymorphisms (SNPs) in 1,341 Dutch Caucasian OA cases and 3,496 ... -
Identification of most important features based on a fuzzy ensemble technique: Evaluation on joint space narrowing progression in knee osteoarthritis patients
(2021)Objective: Feature selection (FS) is a crucial and at the same time challenging processing step that aims to reduce the dimensionality of complex classification or regression problems. Various techniques have been proposed ... -
Interleukin-10G and interleukin-10R microsatellite polymorphisms and osteoarthritis of the knee
(2005)Objective To clarify and evaluate the possible role of interleukin-10G (IL-10G) and interleukin-10R (IL-10R) microsatellite polymorphisms of IL-10 gene in knee osteoarthritis (OA). Methods This was a case-control study. ... -
Is Distribution of Pain Related with Central Sensitization in Patients with Lower Limb Osteoarthritis?
(2021)Design: Cross-sectional study. Background: Osteoarthritis is one of the most common conditions in our society. A growing number of studies suggest the existence of central sensitization (CS) in a subgroup of osteoarthritic ... -
Lack of association of single nucleotide polymorphism in LRCH1 with knee osteoarthritis susceptibility
(2008)A genetic association of knee osteoarthritis (OA) and a C/T transition single nucleotide polymorphism (SNP) (rs912428) located in intron 1 of the LRCH1 gene has recently been reported in European Caucasians; however, the ... -
Large replication study and meta-analyses of DVWA as an osteoarthritis susceptibility locus in European and Asian populations
(2009)Recently, through a genome wide association study in Japanese knee osteoarthritis (OA) cases, a previously unknown gene, DVWA, was identified. The non-synonymous single nucleotide polymorphism (SNP) rs7639618 was subsequently ...