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ABNORMAL EXPRESSION OF C3ORF9 GENE IN PATIENTS WITH MYELODYSPLASTIC SYNDROMES

Karadonta, A. V.; Alexandrakis, M. G.; Kourelis, T. V.; Manola, A.; Garlemou, K.; Stathakis, N. E.; Kyriakou, D. (2009)

Myelodysplastic Syndrome (MDS) cells present genetic instability and dysregulation of the gene C3ORF9, which was isolated from an MDS cDNA library and codes for a putative protein. We studied the expression of C3ORF9 in ...
Posttranslational regulation impacts the fate of duplicated genes

Amoutzias, G. D.; He, Y.; Gordon, J.; Mossialos, D.; Oliver, S. G.; Van de Peer, Y. (2010)

Gene and genome duplications create novel genetic material on which evolution can work and have therefore been recognized as a major source of innovation for many eukaryotic lineages. Following duplication, the most likely ...
The tRNA aminoacylation co-factor Arc1p is excluded from the nucleus by an Xpo1p-dependent mechanism

Galani, K.; Hurt, E.; Simos, G. (2005)

Arc1p, a yeast tRNA-binding protein, forms a complex with the aminoacyl-tRNA synthetases, methionyl tRNA synthetase (MetRS) and glutamyl tRNA synthetase (GluRS). Although this complex localizes normally in the cytoplasm, ...