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Digoxin and Adenosine Triphosphate Enhance the Functional Properties of Tissue-Engineered Cartilage

Makris, E. A.; Huang, B. J.; Hu, J. C.; Chen-Izu, Y.; Athanasiou, K. A. (2015)

Toward developing engineered cartilage for the treatment of cartilage defects, achieving relevant functional properties before implantation remains a significant challenge. Various chemical and mechanical stimuli have been ...
Insulin-Induced Electrophysiology Changes in Human Pleura Are Mediated via Its Receptor

Kouritas, V. K.; Ioannou, M.; Foroulis, C. N.; Desimonas, N.; Evaggelopoulos, K.; Gourgoulianis, K. I.; Molyvdas, P. A.; Hatzoglou, C. (2010)

Background. Insulin directly changes the sheep pleural electrophysiology. The aim of this study was to investigate whether insulin induces similar effects in human pleura, to clarify insulin receptor's involvement, and to ...
Urate crystals induce NLRP3 inflammasome-dependent IL-1 beta secretion and proliferation in isolated primary human T-cells

Eleftheriadis, T.; Pissas, G.; Antoniadi, G.; Makri, P.; Liakopoulos, V.; Stefanidis, I. (2015)

Background: Urate through NOD-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome-dependent caspase-1 activation stimulates macrophages to secrete inteleukin-1 beta (IL-1 beta). Urate also enhances adaptive ...