Listar por autor "Tsakalof, A."
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Assessment of PCBs exposure in human hair using double focusing high resolution mass spectrometry and single quadrupole mass spectrometry
Barbounis, E. G.; Tzatzarakis, M. N.; Alegakis, A. K.; Kokkinaki, A.; Karamanos, N.; Tsakalof, A.; Tsatsakis, A. M. (2012)Polychlorinated biphenyls (PCBs) levels were assessed in human hair samples, originating from two main agricultural regions of Greece. The analysis was performed by gas chromatography-mass spectrometry (GC-MS) and gas ... -
Assessment of synthetic polymeric coatings for the protection and preservation of stone monuments
Tsakalof, A.; Manoudis, P.; Karapanagiotis, I.; Chryssoulakis, I.; Panayiotou, C. (2007)The performance of five synthetic coatings for the protection of stone monuments of Hellenistic and Byzantine period has been evaluated. The selected coatings included four commercially available siloxane-, siloxane/acrylic- ... -
Biomonitoring of organophosphate exposure of pesticide sprayers and comparison of exposure levels with other population groups in Thessaly (Greece)
Koureas, M.; Tsakalof, A.; Tzatzarakis, M.; Vakonaki, E.; Tsatsakis, A.; Hadjichristodoulou, C. (2014)Objectives To evaluate the exposure of different population groups in Thessaly (Greece) to organophosphate pesticides (OPs) and investigate the dependence of exposure levels on pesticide application practices, personal ... -
The Byzantine wall paintings from the protaton church on Mount Athos, Greece: tradition and science
Daniilia, S.; Tsakalof, A.; Bairachtari, K.; Chryssoulakis, Y. (2007)The present work is a study of the wall painting complex in the Protaton Church (1295) on Mount Athos, Greece. These paintings, high in artistic value, are themselves a monument-representative of the Macedonian iconographic ... -
Cobalt induces hypoxia-inducible factor-1 alpha (HIF-1 alpha) in HeLa cells by an iron-independent, but ROS-, PI-3K- and MAPK-dependent mechanism
Triantafyllou, A.; Liakos, P.; Tsakalof, A.; Georgatsou, E.; Simos, G.; Bonanou, S. (2006)The iron-chelator desferrioxamine (DFO) and the transition metal cobalt induce hypoxia-inducible factor-1 alpha (HIF-1 alpha) in normoxia. DFO stabilizes HIF-1 alpha from proteolysis by inhibiting the activity of iron-dependent ... -
Computer simulation based selection of optimal monomer for imprinting of tri-O-acetiladenosine in polymer matrix: vacuum calculations
Barkaline, V. V.; Douhaya, Y. V.; Tsakalof, A. (2013)Molecularly imprinted polymers can be anticipated as synthetic imitation of natural antibodies, receptors and enzymes. In case of successful imprinting the selectivity and affinity of the imprint for substrate molecules ... -
Dermal & inhalation exposure of operators during fungicide application in vineyards. Evaluation of coverall performance
Tsakirakis, A. N.; Kasiotis, K. M.; Charistou, A. N.; Arapaki, N.; Tsatsakis, A.; Tsakalof, A.; Machera, K. (2014)In the present study the dermal and the inhalation exposure of five operators during fungicide applications in vineyards were determined. The produced exposure datasets can be used as surrogate for the estimation of the ... -
The dietary flavonoid kaempferol effectively inhibits HIF-1 activity and hepatoma cancer cell viability under hypoxic conditions
Mylonis, I.; Lakka, A.; Tsakalof, A.; Simos, G. (2010)Hepatocellular carcinoma (HCC) is characterized by high mortality rates and resistance to conventional treatment. HCC tumors usually develop local hypoxia, which stimulates proliferation of cancer cells and renders them ... -
Differential regulation of hypoxia inducible factor 1 alpha (HIF-1 alpha) expression and HeLa cell survival and proliferation by hypoxia, desferrioxamine, cobalt and quercetin: the role of iron
Triantafyllou, A.; Liakos, P.; Tsakalof, A.; Georgatsou, E.; Simos, G.; Bonanou, S. (2005) -
Fabrication of super-hydrophobic surfaces for enhanced stone protection
Manoudis, P. N.; Tsakalof, A.; Karapanagiotis, I.; Zuburtikudis, I.; Panayiotou, C. (2009)In the current study, we demonstrate that the modification of a commercial siloxane protective composition by the addition of silica nanoparticles substantially enhances its protective efficiency and renders the treated ... -
The flavonoid quercetin induces hypoxia-inducible factor-1 alpha (HIF-1 alpha) and inhibits cell proliferation by depleting intracellular iron
Triantafyllou, A.; Liakos, P.; Tsakalof, A.; Chachami, G.; Paraskeva, E.; Molyvdas, P. A.; Georgatsou, E.; Simos, G.; Bonanou, S. (2007)Quercetin, a flavonoid with anti- oxidant, metal chelating, kinase modulating and anti- proliferative properties, can induce hypoxia- inducible factor-1 alpha (HIF-1 alpha) in normoxia, but its mechanism of action has not ... -
Flavonoids induce HIF-1 alpha but impair its nuclear accumulation and activity
Triantafyllou, A.; Mylonis, L.; Simos, G.; Bonanou, S.; Tsakalof, A. (2008)Hypoxia-inducible factor-1 alpha (HIF-1 alpha) is the regulatory subunit of the transcription factor HIF-1, which is highly involved in the pathology of diseases associated with tissue hypoxia. In this study we investigated ... -
FLAVONOIDS: STRUCTURE-BIOACTIVITY ASSOCIATIONS
Tsakalof, A. (2004) -
From Byzantine to post-Byzantine art: the painting technique of St Stephen's wall paintings at Meteora, Greece
Daniilia, S.; Minopoulou, E.; Andrikopoulos, K. S.; Tsakalof, A.; Bairachtari, K. (2008)The old katholikon of St Stephen's monastery at the Meteora (site of the most important complex of monasteries in Greece after Mount Athos) is decorated with wall paintings that date from the beginning of 17th century. In ... -
Identification of red natural dyes in post-byzantine icons by HPLC
Karapanagiotis, I.; Daniffia; Tsakalof, A.; Chryssoulakis, Y. (2005)A high performance liquid chromatography (HPLC) methodology, combined with UV-Vis Diode Array Detection, is developed for the separation and identification of five reddish natural dyestuffs: cochineal, madder, lac dye, ... -
Imidacloprid and 6-chloronicotinic acid determination in blood serum of long-term exposed rabbits using LC-APCI-MS technique
Kavvalakis, M.; Tzatzarakis, M.; Stivaktakis, P.; Bariotaki, A.; Tsakalof, A.; Vardavas, A.; Babatsikou, F.; Vynias, D.; Tsatsakis, A. (2014) -
In vivo evaluation of CYP1A2 CYP2A6, NAT-2 and xanthine oxidase activities in a Greek population sample by the RP-HPLC monitoring of caffeine metabolic ratios
Begas, E.; Kouvaras, E.; Tsakalof, A.; Papakosta, S.; Asprodini, E. K. (2007)A RP-HPLC method was developed for the assessment of caffeine and its metabolites in urine and was used for the evaluation of the CYP1A2, CYP2A6, xanthine oxidase (XO) and N-acetyl-transferase-2 (NAT-2) in vivo activities ... -
Increased levels of oxidative DNA damage in pesticide sprayers in Thessaly Region (Greece). Implications of pesticide exposure
Koureas, M.; Tsezou, A.; Tsakalof, A.; Orfanidou, T.; Hadjichristodoulou, C. (2014)The widespread use of pesticides substances nowadays largely guarantees the protection of crops and people from undesired pests. However, exposure to pesticides was related to a variety of human health effects. The present ... -
Isolation of hypoxia-inducible factor 1 (HIF-1) inhibitors from frankincense using a molecularly imprinted polymer
Lakka, A.; Mylonis, I.; Bonanou, S.; Simos, G.; Tsakalof, A. (2011)Hypoxia-Inducible Factor 1 (HIF-1), a transcriptional activator, is highly involved in the pathology of cancer. Inhibition of HIF-1 retards tumor growth and enhances treatment efficiency when used in combination with chemo- ... -
Molecular Imprinting of Tri-O-Acetyladenosine for the Synthetic Imitation of an ATP-Binding Cleft in Protein Kinases
Lakka, A.; Tsakalof, A. (2013)A number of diseases, including cancer, diabetes, and inflammation, are linked to deregulation of cell signaling pathways controlled by protein kinases. Inhibition of the kinases involved can interrupt aberrant signaling ...