Browsing by Subject "SECONDARY ALCOHOLS"

Now showing items 1-2 of 2

Efficient synthesis of exomethylene- and keto-exomethylene-D-glucopyranosyl nucleoside analogs as potential cytotoxic agents

Tzioumaki, N.; Tsoukala, E.; Manta, S.; Kiritsis, C.; Balzarini, J.; Komiotis, D. (2011)

A novel series of exomethylene- and keto-exomethylene-D-glucopyranonucleosides with thymine, uracil, and 5-fluorouracil as heterocyclic bases have been designed and synthesized. Wittig condensation of the 3-keto glucoside ...
Keto-fluorothiopyranosyl nucleosides: a convenient synthesis of 2-and 4-keto-3-fluoro-5-thioxylopyranosyl thymine analogs

Tsoukala, E.; Manta, S.; Tzioumaki, N.; Kiritsis, C.; Komiotis, D. (2011)

A novel series of fluorinated keto-beta-D-5-thioxylopyranonucleosides bearing thymine as the heterocyclic base have been designed and synthesized. Deprotection of 3-deoxy-3-fluoro-5-S-acetyl-5-thio-D-xylofuranose (1) and ...