• Characteristics and outcomes of cancer patients who develop pulmonary embolism: A cross-sectional study 

      Chlapoutakis S., Georgakopoulou V.E., Trakas N., Kouvelos G., Papalexis P., Damaskos C., Sklapani P., Grivas A., Gouveris P., Tryfonopoulos D., Tzovaras A., Ardavanis-Loukeris G., Grouzi E., Spandidos D.A., Matsagkas M. (2021)
      Pulmonary embolism (PE), along with deep vein thrombosis, are collectively known as venous thromboembo- lism (VTE). Predisposing factors for PE include post-operative conditions, pregnancy, cancer and an advanced age; of ...
    • Clinical outcomes and neuroimaging profiles in nondisabled patients with anticoagulant-related intracerebral hemorrhage 

      Lioutas V.-A., Goyal N., Katsanos A.H., Krogias C., Zand R., Sharma V.K., Varelas P., Malhotra K., Paciaroni M., Sharaf A., Chang J., Karapanayiotides T., Kargiotis O., Pappa A., Mai J., Pandhi A., Schroeder C., Tsantes A., Mehta C., Kerro A., Khan A., Mitsias P.D., Selim M.H., Alexandrov A.V., Tsivgoulis G. (2018)
      Background and Purpose: The aim of this study was to prospectively validate our prior findings of smaller hematoma volume and lesser neurological deficit in nonvitamin K oral anticoagulant (NOAC) compared with Vitamin K ...
    • Closure of patent foramen ovale versus medical therapy in patients with cryptogenic stroke or transient ischemic attack: Updated systematic review and meta-analysis 

      Ntaios G., Papavasileiou V., Sagris D., Makaritsis K., Vemmos K., Steiner T., Michel P. (2018)
      Background and Purpose: Previous systematic reviews and meta-analyses compared the efficacy and safety of patent foramen ovale (PFO) closure versus medical treatment in patients with cryptogenic stroke or transient ischemic ...
    • Coagulation, angiogenesis, and venous thromboembolism in cancer [10] 

      Agorogiannis, E. I.; Agorogiannis, G. I. (2002)
    • Comparable or higher prevalence of comorbidities in antiphospholipid syndrome vs rheumatoid arthritis: A multicenter, case-control study 

      Panopoulos S., Thomas K., Georgiopoulos G., Boumpas D., Katsiari C., Bertsias G., Drosos A.A., Boki K., Dimitroulas T., Garyfallos A., Papagoras C., Katsimbri P., Tziortziotis A., Adamichou C., Kaltsonoudis E., Argyriou E., Vosvotekas G., Sfikakis P.P., Vassilopoulos D., Tektonidou M.G. (2021)
      Objectives: Evidence on comorbidity prevalence in antiphospholipid syndrome (APS) and its difference from high comorbidity burden rheumatic diseases is limited. Herein, we compare multiple comorbidities between APS and RA. ...
    • Consensus statements and recommendations from the ESO-Karolinska Stroke Update Conference, Stockholm 11–13 November 2018 

      Ahmed N., Audebert H., Turc G., Cordonnier C., Christensen H., Sacco S., Sandset E.C., Ntaios G., Charidimou A., Toni D., Pristipino C., Köhrmann M., Kuramatsu J.B., Thomalla G., Mikulik R., Ford G.A., Martí-Fàbregas J., Fischer U., Thoren M., Lundström E., Rinkel G.J.E., Worp H.B.V.D., Matusevicius M., Tsivgoulis G., Milionis H., Rubiera M., Hart R., Moreira T., Lantz M., Sjöstrand C., Andersen G., Schellinger P., Kostulas K., Sunnerhagen K.S., Keselman B., Korompoki E., Purrucker J., Khatri P., Whiteley W., Berge E., Mazya M., Dippel D.W.J., Mustanoja S., Rasmussen M., Söderqvist Å.K., Escudero-Martínez I., Steiner T. (2019)
      The purpose of the European Stroke Organisation–Karolinska Stroke Update Conference is to provide updates on recent stroke therapy research and to give an opportunity for the participants to discuss how these results may ...
    • Cost-Effectiveness Analysis of Rivaroxaban for Treatment of Deep Vein Thrombosis and Pulmonary Embolism in Greece 

      Gourzoulidis G., Kourlaba G., Kakisis J., Matsagkas M., Giannakoulas G., Gourgoulianis K.I., Vassilakopoulos T., Maniadakis N. (2017)
      Background and Objective: Venous thromboembolism (VTE), comprising deep-vein thrombosis (DVT) and pulmonary embolism (PE), is a major healthcare concern that results in substantial morbidity and mortality with great economic ...
    • COVID-19 hemodynamic and thrombotic effect on the eye microcirculation after hospitalization: A quantitative case-control study 

      Koutsiaris A.G., Riri K., Boutlas S., Panagiotou T.N., Kotoula M., Daniil Z., Tsironi E.E. (2022)
      BACKGROUND OBJECTIVE: To quantify the hemodynamic and thrombotic effect of COVID-19 on the eye microcirculation of patients with thromboprophylaxis, shortly after hospital discharge. METHODS: This case-control study included ...
    • Data-driven machine-learning analysis of potential embolic sources in embolic stroke of undetermined source 

      Ntaios G., Weng S.F., Perlepe K., Akyea R., Condon L., Lambrou D., Sirimarco G., Strambo D., Eskandari A., Karagkiozi E., Vemmou A., Korompoki E., Manios E., Makaritsis K., Vemmos K., Michel P. (2021)
      Background and purpose: Hierarchical clustering, a common ‘unsupervised’ machine-learning algorithm, is advantageous for exploring potential underlying aetiology in particularly heterogeneous diseases. We investigated ...
    • Difficult situations in anticoagulation after stroke: Between Scylla and Charybdis 

      Ntaios G., Lip G.Y.H. (2016)
      Purpose of review A significant proportion of stroke patients is treated with anticoagulants for secondary stroke prevention. Often, in such patients, stroke physicians are required to make difficult clinical decisions ...
    • Direct oral anticoagulant-vs Vitamin K antagonist-related nontraumatic intracerebral hemorrhage 

      Tsivgoulis G., Lioutas V.-A., Varelas P., Katsanos A.H., Goyal N., Mikulik R., Barlinn K., Krogias C., Sharma V.K., Vadikolias K., Dardiotis E., Karapanayiotides T., Pappa A., Zompola C., Triantafyllou S., Kargiotis O., Ioakeimidis M., Giannopoulos S., Kerro A., Tsantes A., Mehta C., Jones M., Schroeder C., Norton C., Bonakis A., Chang J., Alexandrov A.W., Mitsias P., Alexandrov A.V. (2017)
      Objective: To compare the neuroimaging profile and clinical outcomes among patients with intracerebral hemorrhage (ICH) related to use of vitamin K antagonists (VKAs) or direct oral anticoagulants (DOACs) for nonvalvular ...
    • Early recurrence and major bleeding in patients with acute ischemic stroke and atrial fibrillation treated with Non-Vitamin-K oral anticoagulants (RAF-NOACs) Study 

      Paciaroni M., Agnelli G., Falocci N., Tsivgoulis G., Vadikolias K., Liantinioti C., Chondrogianni M., Bovi P., Carletti M., Cappellari M., Zedde M., Ntaios G., Karagkiozi E., Athanasakis G., Makaritsis K., Silvestrelli G., Lanari A., Ciccone A., Putaala J., Tomppo L., Tatlisumak T., Abdul-Rahim A.H., Lees K.R., Alberti A., Venti M., Acciarresi M., D'Amore C., Becattini C., Mosconi M.G., Cimini L.A., Soloperto R., Masotti L., Vannucchi V., Lorenzini G., Tassi R., Guideri F., Acampa M., Martini G., Sohn S.-I., Marcheselli S., Mumoli N., De Lodovici M.L., Bono G., Furie K.L., Tadi P., Yaghi S., Toni D., Letteri F., Tassinari T., Kargiotis O., Lotti E.M., Flomin Y., Mancuso M., Maccarrone M., Giannini N., Bandini F., Pezzini A., Poli L., Padovani A., Scoditti U., Denti L., Consoli D., Galati F., Sacco S., Carolei A., Tiseo C., Gourbali V., Orlandi G., Giuntini M., Chiti A., Giorli E., Gialdini G., Corea F., Ageno W., Bellesini M., Colombo G., Monaco S., Baronello M.M., Karapanayiotides T., Caso V. (2017)
      Background--The optimal timing to administer non-vitamin K oral anticoagulants (NOACs) in patients with acute ischemic stroke and atrial fibrillation is unclear. This prospective observational multicenter study evaluated ...
    • Early recurrence in paroxysmal versus sustained atrial fibrillation in patients with acute ischaemic stroke 

      Paciaroni M., Angelini F., Agnelli G., Tsivgoulis G., Furie K.L., Tadi P., Becattini C., Falocci N., Zedde M., Abdul-Rahim A.H., Lees K.R., Alberti A., Venti M., Acciarresi M., Altavilla R., D’Amore C., Mosconi M.G., Cimini L.A., Bovi P., Carletti M., Rigatelli A., Cappellari M., Putaala J., Tomppo L., Tatlisumak T., Bandini F., Marcheselli S., Pezzini A., Poli L., Padovani A., Masotti L., Vannucchi V., Sohn S.-I., Lorenzini G., Tassi R., Guideri F., Acampa M., Martini G., Ntaios G., Karagkiozi E., Athanasakis G., Makaritsis K., Vadikolias K., Liantinioti C., Chondrogianni M., Mumoli N., Consoli D., Galati F., Sacco S., Carolei A., Tiseo C., Corea F., Ageno W., Bellesini M., Silvestrelli G., Ciccone A., Scoditti U., Denti L., Mancuso M., Maccarrone M., Orlandi G., Giannini N., Gialdini G., Tassinari T., Lodovici M.L.D., Bono G., Rueckert C., Baldi A., Toni D., Letteri F., Giuntini M., Lotti E.M., Flomin Y., Pieroni A., Kargiotis O., Karapanayiotides T., Monaco S., Baronello M.M., Csiba L., Szabó L., Chiti A., Giorli E., Sette M.D., Imberti D., Zabzuni D., Doronin B., Volodina V., Michel Pd-Mer P., Vanacker P., Barlinn K., Pallesen L.P., Kepplinger J., Deleu D., Melikyan G., Ibrahim F., Akhtar N., Gourbali V., Yaghi S., Caso V. (2019)
      Background: The relationship between different patterns of atrial fibrillation and early recurrence after an acute ischaemic stroke is unclear. Purpose: In a prospective cohort study, we evaluated the rates of early ischaemic ...
    • Early versus Late initiation of direct oral Anticoagulants in post-ischaemic stroke patients with atrial fibrillatioN (ELAN): Protocol for an international, multicentre, randomised-controlled, two-arm, open, assessor-blinded trial 

      Fischer U., Trelle S., Branca M., Salanti G., Paciaroni M., Ferrari C., Abend S., Beyeler S., Strbian D., Thomalla G., Ntaios G., Bonati L.H., Michel P., Nedeltchev K., Gattringer T., Sandset E.C., Kelly P., Lemmens R., Koga M., Sylaja P.N., de Sousa D.A., Bornstein N.M., Gdovinova Z., Seiffge D.J., Gralla J., Horvath T., Dawson J. (2022)
      Rationale: Direct oral anticoagulants (DOAC) are highly effective in preventing ischaemic strokes in people with atrial fibrillation (AF). However, it is unclear how soon they should be started after acute ischaemic stroke ...
    • Effectiveness and safety of intracranial events associated with the use of direct oral anticoagulants for atrial fibrillation: A systematic review and meta-analysis of 92 studies 

      Archontakis-Barakakis P., Li W., Kalaitzoglou D., Tzelves L., Manolopoulos A., Giannopoulos S., Giamouzis G., Giannakoulas G., Batsidis A., Palaiodimos L., Ntaios G., Lip G.Y.H., Kokkinidis D.G. (2022)
      Aims: Observational studies have investigated the effectiveness and safety of direct oral anticoagulants (DOACs) and vitamin K antagonists (VKAs) used in nonvalvular atrial fibrillation. We performed a systematic review ...
    • Efficacy and Safety of Heparinization before Deployment of Endograft for Blunt Traumatic Aortic Injury in Severely Injured Patients 

      Makaloski V., Widenka H., Schönhoff F., Spanos K., Wyss T.R., Schmidli J. (2021)
      Background: The administration of unfractionated heparin (UFH) during endovascular repair of blunt traumatic aortic injury (BTAI) is controversial. The aim of the study is to report the early outcomes of patients undergoing ...
    • Efficacy of rivaroxaban in prevention of post-thrombotic syndrome: A systematic review and meta-analysis 

      Karathanos C., Nana P., Spanos K., Kouvelos G., Brotis A., Matsagas M., Giannoukas A. (2021)
      Objective: Direct oral anticoagulants (DOACs) have been recommended for the treatment of deep vein thrombosis (DVT). However, the benefits are uncertain for the prevention of post-thrombotic syndrome (PTS). We performed a ...
    • Embolic Stroke 

      Ntaios G., Hart R.G. (2017)
      [No abstract available]
    • Embolic Stroke of Undetermined Source: A Systematic Review and Clinical Update 

      Hart R.G., Catanese L., Perera K.S., Ntaios G., Connolly S.J. (2017)
      Background and Purpose-Embolic stroke of undetermined source (ESUS) designates patients with nonlacunar cryptogenic ischemic strokes in whom embolism is the likely stroke mechanism. It has been hypothesized that anticoagulation ...
    • Embolic Stroke of Undetermined Source: JACC Review Topic of the Week 

      Ntaios G. (2020)
      The term embolic stroke of undetermined source (ESUS) was introduced in 2014 to describe patients with a nonlacunar ischemic stroke and no convincing etiology. The terms ESUS and cryptogenic stroke are not synonyms, as the ...