Πλοήγηση ανά Θέμα "SURVIVAL"
Αποτελέσματα 21-40 από 48
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High intratumoural accumulation of stealth (R) liposomal doxorubicin (Caelyx (R)) in glioblastomas and in metastatic brain tumours
(2000)The blood-brain barrier is a major obstacle for the chemotherapeutic drugs to effectively reach primary or secondary brain tumours. Stealth(R) liposomal drugs are highly accumulated in tumoural tissues. In the present study ... -
The Indoleamine 2,3-dioxygenase Inhibitor 1-methyl-tryptophan Suppresses Mitochondrial Function, Induces Aerobic Glycolysis and Decreases Interleukin-10 Production in Human Lymphocytes
(2012)Background: Indoleamine 2,3-dioxygenase (IDO) suppresses adaptive immunity. It is known that IDO induces T-cell differentiation to regulatory T-cells (Treg) through tryptophan depletion and/or kynurenine pathway products. ... -
Inhibition of indoleamine 2,3-dioxygenase in mixed lymphocyte reaction affects glucose influx and enzymes involved in aerobic glycolysis and glutaminolysis in alloreactive T-cells
(2013)Indoleamine 2,3-dioxygenase (IDO) suppresses adaptive immunity. T-cell proliferation and differentiation to effector cells require increased glucose consumption, aerobic glycolysis and glutaminolysis. The effect of IDO on ... -
Inter-comparison of the potentially active prokaryotic communities in the halocline sediments of Mediterranean deep-sea hypersaline basins
(2015)The sediment microbiota of the Mediterranean deep-sea anoxic hypersaline basins (DHABs) are understudied relative to communities in the brines and halocline waters. In this study, the active fraction of the prokaryotic ... -
Intraoperative radiation therapy on pancreatic cancer patients: a review of the literature
(2011)Pancreatic cancer is rarely curable, and the overall survival rate at 5 years is under 4%. This study aimed to assess the efficacy, effectiveness and safety of intraoperative radiation therapy (IORT) as treatment in ... -
Intraperitoneal Dissemination of Endometrial Cancer Cells After Hysteroscopy A Systematic Review and Meta-Analysis
(2010)Introduction: Hysteroscopy is a diagnostic procedure with a high accuracy in diagnosing endometrial cancer. Because of the increase of intrauterine pressure during distention media inflation, several retrospective studies ... -
Investigation of attenuation correction in SPECT using textural features, Monte Carlo simulations, and computational anthropomorphic models
(2015)PurposeTo present and evaluate a new methodology to investigate the effect of attenuation correction (AC) in single-photon emission computed tomography (SPECT) using textural features analysis, Monte Carlo techniques, and ... -
Lessons learnt from the autopsies of 445 cases of sudden cardiac death in adults
(2005)Aim To determine the cause of sudden cardiac death in adults who underwent autopsy. Methods Four hundred and forty-five sudden cardiac deaths occurred within 1 h of the symptoms onset, and all other cardiac and noncardiac ... -
Lupus thrombocytopenia: clinical implications and prognostic significance
(2005)Objectives: To clarify clinical manifestations, association with disease activity, and prognostic impact of thrombocytopenia using simple and reliable indices. Methods: 632 patients were reviewed retrospectively. Fifty ... -
Motor signs predict poor outcomes in Alzheimer disease
(2005)Objective: To examine whether the presence of motor signs has predictive value for important outcomes in Alzheimer disease (AD). Methods: A total of 533 patients with AD at early stages (mean Folstein Mini-Mental State ... -
Pagellus erythrinus (common pandora): a promising candidate species for enlarging the diversity of aquaculture production
(2004)The euryhaline species Pagellus erythrinus was investigated for potential use in aquaculture. The research focused on the biological aspects of the species examining its adaptability in captivity, examining reproduction, ... -
Predictive value of telomerase reverse transcriptase expression in patients with high risk superficial bladder cancer treated with adjuvant BCG immunotherapy
(2009)We conducted a prospective study to determine whether expression of telomerase reverse transcriptase (hTERT) is associated with recurrence-free-survival (RFS) or development of invasive disease in patients with high risk ... -
Prevalence of Pulmonary Hypertension in Patients with Idiopathic Pulmonary Fibrosis: Correlation with Physiological Parameters
(2011)The aim of this study was to prospectively evaluate the prevalence of pulmonary hypertension (PH) in patients with idiopathic pulmonary fibrosis (IPF). One hundred thirty-nine patients (101 male, mean age = 68.6 +/- A 9 ... -
Previous Bladder Cancer History in Patients with High-Risk, Non-muscle-invasive Bladder Cancer Correlates with Recurrence and Progression: Implications of Natural History
(2015)Purpose The purpose of this study was to assess the correlation of previous bladder cancer history with the recurrence and progression of patients with high-risk non-muscle-invasive bladder cancer treated with adjuvant ... -
Prognostic role of angiogenesis in operable carcinoma of the gallbladder
(2002)The prognostic significance of intratumoral angiogenesis was investigated in 62 patients with stage I-III carcinomas of the gallbladder treated with simple cholecystectomy. Microvessel density (MVD) was assessed ... -
Prognostic Significance of Serum Inflammatory Response Markers in Newly Diagnosed Non-Small Cell Lung Cancer before Chemoirradiation
(2015)Purpose. To identify whether the serum's baseline C-reactive protein (CRP) and albumin (Alb) levels related to clinicopathological parameters and overall survival (OS) in non-small cell lung cancer (NSCLC). Methods. In ... -
Prognostic Value of MRS Metabolites in Postoperative Irradiated High Grade Gliomas
(2015)Purpose. We studied the prognostic significance of Magnetic Resonance Spectroscopy (MRS) in operated high grade gliomas. Materials and Methods. Twelve patients were treated with radiotherapy and Temozolomide. The MRS data ... -
Ras suppressor-1 promotes apoptosis in breast cancer cells by inhibiting PINCH-1 and activating p53-upregulated-modulator of apoptosis (PUMA); verification from metastatic breast cancer human samples
(2015)Metastasis, responsible for most deaths from breast cancer (BC), is a multistep process leading to cancer cell spread. Extracellular matrix (ECM)-related adhesion and apoptosis resistance play pivotal role in metastasis. ... -
Regional differences in mortality in Greece (1984-2004): The case of Thrace
(2008)Background: Mortality differences at national level can generate hypothesis on possible causal association that could be further investigated. The aim of the present study was to identify regions with high mortality rates ... -
Restless legs syndrome does not affect 3-year mortality in hemodialysis patients
(2015)Objective: Uremic restless legs syndrome (RLS) has been related to an enhanced mortality of hemodialysis (HD) patients. In the general population studies of this association have yielded inconsistent results. The aim of ...