Πλοήγηση ανά Θέμα "RNA"
Αποτελέσματα 21-40 από 80
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Ensemble classification through random projections for single-cell RNA-seq data
(2020)Nowadays, biomedical data are generated exponentially, creating datasets for analysis with ultra-high dimensionality and complexity. An indicative example is emerging single-cell RNA-sequencing (scRNA-seq) technology, which ... -
The enzymatic activity of SR protein kinases 1 and 1a is negatively affected by interaction with scaffold attachment factors B1 and 2
(2009)SR protein kinases (SRPKs) phosphorylate Ser/Arg dipeptide-containing proteins that play crucial roles in a broad spectrum of basic cellular processes. Phosphorylation by SRPKs constitutes a major way of regulating such ... -
Evolution of a rare vaccine-derived multirecombinant poliovirus
(2005)Recombination is one of the mechanisms by which viral genomes evolve. A vaccine-derived multirecombinant poliovirus strain was isolated from a 5-month-old child with vaccine-associated paralytic poliomyelitis after oral ... -
An extension of fuzzy topological approach for comparison of genetic sequences
(2015)Bioinformatics is a relatively new discipline where Mathematics are applied in the analysis of genetic sequences. The analysis of the genetic material of living organisms which consist of nucleic acids DNA and RNA is of ... -
fbl Gene as a Species-Specific Target for Staphylococcus lugdunensis Identification
(2010)Staphylococcus lugdunensis is an unusually virulent coagulase-negative species, associated with severe infections The present report describes the development of a single-step, species-specific PCR protocol for S. lugdunensis ... -
Feature Selection in Single-Cell RNA-seq Data via a Genetic Algorithm
(2021)Big data methods prevail in the biomedical domain leading to effective and scalable data-driven approaches. Biomedical data are known for their ultra-high dimensionality, especially the ones coming from molecular biology ... -
Fuzzy polynucleotide spaces and metrics
(2006)The study of genetic sequences is of great importance in biology and medicine. Mathematics is playing all important role in the study of genetic sequences and. generally, in bioinformatics. In this paper, we extend the ... -
Genetic variability of encephalomyocarditis virus (EMCV) isolates
(2006)In order to evaluate the variability of encephalomyocarditis virus (EMCV), field isolates originating from different European regions and inducing different clinical pictures in pigs have been molecularly characterised. ... -
Genomic analysis of recombinant Sabin clinical isolates
(2006)Recombination in Poliovirus vaccine strains is a very frequent phenomenon. In this report 23 polio/Sabin strains isolated from healthy vaccinees or from VAPP patients after OPV administration, were investigated in order ... -
Hypoxia upregulates integrin gene expression in microvascular endothelial cells and promotes their migration and capillary-like tube formation
(2017)Tissue hypoxia affects gene expression through the hypoxia-inducible transcription factors, HIF-1 and HIF-2, in both physiological and pathological angiogenesis. Angiogenesis is a complex response of endothelial cells ... -
An immunocompetent patient presenting with severe septic arthritis due to Ralstonia pickettii identified by molecular-based assays: A case report
(2009)Introduction: Ralstonia pickettii is an infrequent pathogen of invasive infections in healthy individuals. The microorganism is supposed to be of relatively low virulence, but can cause infections, mainly of the respiratory ... -
Important disease conditions of newly cultured species in intensive freshwater farms in Greece: first incidence of nodavirus infection in Acipenser sp
(2004)We describe here the main pathological conditions of freshwater fish recently introduced for intensive rearing (open ponds and recirculating freshwater systems) in Greece. Sturgeon were susceptible to skeletal abnormalities ... -
Improved genotyping vaccine and wild-type poliovirus strains by restriction fragment length polymorphism analysis: Clinical diagnostic implications
(2000)The combination of preventive vaccination and diagnostic typing of viral isolates from patients with clinical poliomyelitis constitutes our main protective shield against polioviruses. The restriction fragment length ... -
In silico methods for the identification of diagnostic and favorable prognostic markers in acute myeloid leukemia
(2021)Acute myeloid leukemia (AML), the most common type of acute leukemia in adults, is mainly asymptomatic at early stages and progresses/recurs rapidly and frequently. These attributes necessitate the identification of ... -
Inactivation, removal, and regrowth potential of opportunistic pathogens and antimicrobial resistance genes in recycled water systems
(2021)With two thirds of the global population living in areas affected by water scarcity, wastewater reuse is actively being implemented or explored by many nations. There is a need to better understand the efficacy of recycled ... -
Inhibition of mRNA deadenylation by the nuclear cap binding complex (CBC)
(2006)Poly(A)-specific ribonuclease (PARN) is a cap-interacting and poly(A)-specific 3′-exoribonuclease. Here we have investigated how the cap binding complex (CBC) affects human PARN activity. We showed that CBC, via its 80-kDa ... -
Insights into the function and horizontal transfer of isoproturon degradation genes (pdmAB) in a biobed system
(2020)Biobeds, designed to minimize pesticide point source contamination, rely mainly on biodegradation processes. We studied the interactions of a biobed microbial community with the herbicide isoproturon (IPU) to explore the ... -
Intelligent identification of biomarkers for the study of obstructive nephropathy
(2013)Obstructive Nephropathy (ON) is a renal disease, which pathological profile is the result of various, tightly coupled and co-regulated, molecular processes, pervading various layers of molecular dissection. In this context, ... -
Internal translation initiation stimulates expression of the ARF/core+1 open reading frame of HCV genotype 1b
(2011)The hepatitis C virus possesses an alternative open reading frame overlapping the Core gene, whose products are referred to as Core+1 or alternative reading frame (ARF) or F protein(s). Extensive studies on genotype HCV-1 ... -
Isolation and characterization of a protein from Mendole (Spicara maena) eggs that binds to DNA and inhibits its replication as well as its acid precipitation
(2001)Proteins that bind and protect nucleic acids from acid precipitation have been characterized from human and mouse plasma. In the present study one protein from Mendole (Spicara maena) eggs was purified to homogeneity, by ...