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    • Partial 3D gene sequences of Coxsackie viruses reveal interspecies exchanges 

      Bolanaki, E.; Kottaridi, C.; Markoulatos, P.; Kyriakopoulou, Z.; Margaritis, L.; Katsorchis, T. (2007)
      The 3D region of 46 clinical Coxsackievirus strains, primarily belonging to the human enterovirus B species (HEV-B), were analyzed using nucleotide distance matrices and phylogeny software. The conclusions from previously ...
    • Phylogenetic correlation of Greek and Italian orf virus isolates based on VIR gene 

      Kottaridi, C.; Nomikou, K.; Teodori, L.; Savini, G.; Lelli, R.; Markoulatos, P.; Mangana, O. (2006)
      Thirteen orf virus isolates obtained during the time period between 1995 and 2004 from crusted scab lesions of nine sheep and four goats from different geographical areas of Greece and Italy with suspected contagious ecthyma ...
    • Phylogeography of roe deer (Capreolus capreolus) populations: The effects of historical genetic subdivisions and recent nonequilibrium dynamics 

      Randi, E.; Alves, P. C.; Carranza, J.; Milosevic-Zlatanovi, S.; Sfougaris, A.; Mucci, N. (2004)
      We sequenced 704 mitochondrial DNA (mtDNA) control-region nucleotides and genotyped 11 autosomal microsatellites (STR) in 617 European roe deer (Capreolus capreolus) samples, aiming to infer the species' phylogeographical ...
    • Primary biliary cirrhosis is characterized by IgG3 antibodies cross-reactive with the major mitochondrial autoepitope and its lactobacillus mimic 

      Bogdanos, D. P.; Baum, H.; Okamoto, M.; Montalto, P.; Sharma, U. C.; Rigopoulou, E. I.; Vlachogiannakos, J.; Ma, Y.; Burroughs, A. K.; Vergani, D. (2005)
      The serological hallmark of primary biliary cirrhosis (PBC) is the presence of pyruvate dehydrogenase complex E2 subunit (PDC-E2) antimitochondrial antibodies (AMAs). Anti-PDC-E2 antibodies cross-react specifically with ...
    • Prion protein gene polymorphisms in healthy and scrapie-affected sheep in Greece 

      Billinis, C.; Psychas, V.; Leontides, L.; Spyrou, V.; Argyroudis, S.; Vlemmas, I.; Leontides, S.; Sklaviadis, T.; Papadopoulos, O. (2004)
      A total of 216 local crossbred sheep from 16 scrapie-affected Greek flocks and 210 purebred sheep of the milk breeds Chios and Karagouniko from healthy flocks were analysed for scrapie-linked polymorphisms in the prion ...
    • Purification of a candidate gonadotrophin surge attenuating factor from human follicular fluid 

      Pappa, A.; Seferiadis, K.; Fotsis, T.; Shevchenko, A.; Marselos, M.; Tsolas, O.; E.messinis, I. (1999)
      Gonadotrophin surge attenuating factor (GnSAF) is a new non-steroidal ovarian substance, different from inhibin, which attenuates the pre-ovulatory luteinizing hormone (LH) surge in superovulated women. Human follicular ...
    • Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration 

      Ratnapriya, R.; Zhan, X.; Fariss, R. N.; Branham, K. E.; Zipprer, D.; Chakarova, C. F.; Sergeev, Y. V.; Campos, M. M.; Othman, M.; Friedman, J. S.; Maminishkis, A.; Waseem, N. H.; Brooks, M.; Rajasimha, H. K.; Edwards, A. O.; Lotery, A.; Klein, B. E.; Truitt, B. J.; Li, B.; Schaumberg, D. A.; Morgan, D. J.; Morrison, M. A.; Souied, E.; Tsironi, E. E.; Grassmann, F.; Fishman, G. A.; Silvestri, G.; Scholl, H. P. N.; Kim, I. K.; Ramke, J.; Tuo, J.; Merriam, J. E.; Merriam, J. C.; Park, K. H.; Olson, L. M.; Farrer, L. A.; Johnson, M. P.; Peachey, N. S.; Lathrop, M.; Baron, R. V.; Igo, R. P.; Klein, R.; Hagstrom, S. A.; Kamatani, Y.; Martin, T. M.; Jiang, Y.; Conley, Y.; Sahel, J. A.; Zack, D. J.; Chan, C. C.; Pericak-Vance, M. A.; Jacobson, S. G.; Gorin, M. B.; Klein, M. L.; Allikmets, R.; Iyengar, S. K.; Weber, B. H.; Haines, J. L.; Léveillard, T.; Deangelis, M. M.; Stambolian, D.; Weeks, D. E.; Bhattacharya, S. E.; Chew, E. Y.; Heckenlively, J. R.; Abecasis, G. R.; Swaroop, A. (2014)
      Neurodegenerative diseases affecting the macula constitute amajor cause of incurable vision loss and exhibit considerable clinical and genetic heterogeneity, from early-onset monogenic disease to multifactorial lateonset ...
    • Role of Arc1p in the modulation of yeast glutamyl-tRNA synthetase activity 

      Graindorge, J. S.; Senger, B.; Tritch, D.; Simos, G.; Fasiolo, F. (2005)
      Yeast methionyl-tRNA synthetase (MetRS) and glutamyl-tRNA synthetase (GluRS) possess N-terminal extensions that bind the cofactor Arc1p in trans. The strength of GluRS-Arc1p interaction is high enough to allow copurification ...
    • Sad3 and Sad4 are required for saponin biosynthesis and root development in oat 

      Mylona, P.; Owatworakit, A.; Papadopoulou, K.; Jenner, H.; Qin, B.; Findlay, K.; Hill, L.; Qi, X.; Bakht, S.; Melton, R.; Osbourn, A. (2008)
      Avenacins are antimicrobial triterpene glycosides that are produced by oat (Avena) roots. These compounds confer broad-spectrum resistance to soil pathogens. Avenacin A-1, the major avenacin produced by oats, is strongly ...
    • A serine carboxypeptidase-like acyltransferase is required for synthesis of antimicrobial compounds and disease resistance in oats 

      Mugford, S. T.; Qi, X.; Bakht, S.; Hill, L.; Wegel, E.; Hughes, R. K.; Papadopoulou, K.; Melton, R.; Philo, M.; Sainsbury, F.; Lomonossoff, G. P.; Roy, A. D.; Goss, R. J. M.; Osbourn, A. (2009)
      Serine carboxypeptidase-like (SCPL) proteins have recently emerged as a new group of plant acyltransferases. These enzymes share homology with peptidases but lack protease activity and instead are able to acylate natural ...
    • A unique hydrophobic cluster near the active site contributes to differences in borrelidin inhibition, among threonyl-tRNA synthetases 

      Ruan, B.; Bovee, M. L.; Sacher, M.; Stathopoulos, C.; Poralla, K.; Francklyn, C. S.; Söll, D. (2005)
      Borrelidin, a compound with anti-microbial and anti-angiogenic properties, is a known inhibitor of bacterial and eukaryal threonyl-tRNA synthetase (ThrRS). The inhibition mechanism of borrelidin is not well understood. ...
    • Vaccine derived bi- and multi-recombinant Sabin strains 

      Paximadi, E.; Karakasiliotis, I.; Bolanaki, E.; Krikelis, A.; Markoulatos, P. (2007)
      A retrospective analysis of five Sabin intertypic recombinant strains, isolated from human feacal specimens during the time period 1978-1985 in Greece, was performed by RT-PCR, Restriction Fragment Length Polymorphism ...
    • VIM-12, a novel plasmid-mediated metallo-β-lactamase from Klebsiella pneumoniae that resembles a VIM-1/VIM-2 hybrid 

      Pournaras, S.; Ikonomidis, A.; Tzouvelekis, L. S.; Tokatlidou, D.; Spanakis, N.; Maniatis, A. N.; Legakis, N. J.; Tsakris, A. (2005)
      A transferable plasmid from Klebsiella pneumoniae carried a class 1 integron containing blaVIM-12, a novel blaVIM-type gene, flanked by two copies of aacA7. blaVIM-12 was clustered between bla-VIM-1 and bla-VIM-2 and ...