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    • Administration of an oral hydration solution prevents electrolyte and fluid disturbances and reduces readmissions in patients with a diverting ileostomy after colorectal surgery: A prospective, randomized, controlled trial 

      Migdanis A., Koukoulis G., Mamaloudis I., Baloyiannis I., Migdanis I., Kanaki M., Malissiova E., Tzovaras G. (2018)
      BACKGROUND: Patients with a newly formed ileostomy often develop electrolyte abnormalities and dehydration. OBJECTIVE: The study assessed the prophylactic effect of an isotonic hydration solution on dehydration and electrolyte ...

    • Administration of low-molecular-weight heparin in patients with two or more unsuccessful IVF/ICSI cycles: a multicenter cohort study 

      Siristatidis C., Dafopoulos K., Salamalekis G., Galazios G., Christoforidis N., Moustakarias T., Koutlaki N., Bouschanetzis C., Loutradis D., Drakakis P. (2018)
      To compare the effects of the administration of low-molecular-weight heparin (LMWH) in subfertile patients with two or more unsuccessful IVF/ICSI cycles. In this six-center two-arm retrospective cohort study, the study ...

    • Administration of prednisolone and low molecular weight heparin in patients with repeated implantation failures: a cohort study 

      Siristatidis C., Dafopoulos K., El-Khayat W., Salamalekis G., Anifandis G., Vrantza T., Elsadek M., Papantoniou N. (2018)
      Conflicting results exist for low molecular weight heparin (LMWH) and prednisolone when tested as separate adjuncts for the improvement of the clinical outcomes in patients with repeated implantation failures (RIF) undergoing ...

    • Adrenal glands of mice and rats: A comparative morphometric study 

      Siasios A., Delis G., Tsingotjidou A., Pourlis A., Grivas I. (2022)
      Mice and rats are among the most used laboratory animals. They share numerous similarities along with differences, some yet unexplored. One of them is the morphometry of their adrenal glands, whose characteristics may be ...

    • Age dependence of brachial cuff-based ambulatory PWV in end-stage kidney disease patients undergoing long-term peritoneal dialysis 

      Vaios V., Georgianos P.I., Vareta G., Divanis D., Dounousi E., Eleftheriadis T., Papagianni A., Zebekakis P.E., Liakopoulos V. (2022)
      Background: The newly introduced device Mobil-O-Graph (IEM, Stolberg, Germany) combines brachial cuff oscillometry and pulse wave analysis, enabling the determination of pulse wave velocity (PWV) via complex mathematic ...

    • Age differences in cardiac autonomic regulation during intermittent exercise in the heat 

      Kaltsatou A., Flouris A.D., Herry C.L., Notley S.R., Seely A.J.E., Beatty H.W., Kenny G.P. (2020)
      Purpose: This study aimed to detect potential differences in heart-rate variability (HRV) during a moderate-intensity intermittent exercise in the heat among physically active young (25.8 ± 1.9 years), middle-aged (43.5 ± ...

    • Age, Body Mass Index, and Daytime and Nocturnal Hypoxia as Predictors of Hypertension in Patients With Obstructive Sleep Apnea 

      Natsios G., Pastaka C., Vavougios G., Zarogiannis S.G., Tsolaki V., Dimoulis A., Seitanidis G., Gourgoulianis K.I. (2016)
      A growing body of evidence links obstructive sleep apnea (OSA) with hypertension. The authors performed a retrospective cohort study using the University Hospital of Larissa Sleep Apnea Database (1501 patients) to determine ...

    • Age, sex, adult and larval diet shape starvation resistance in the Mediterranean fruit fly: an ecological and gerontological perspective 

      Gerofotis C.D., Kouloussis N.A., Koukougiannidou C., Papadopoulos N.T., Damos P., Koveos D.S., Carey J.R. (2019)
      The ability of an animal to withstand periods of food deprivation is a key driver of invasion success (biodiversity), adaptation to new conditions, and a crucial determinant of senescence in populations. Starvation resistance ...

    • Age- A nd sex-specific analysis of patients with embolic stroke of undetermined source 

      Ntaios G., Lip G.Y.H., Vemmos K., Koroboki E., Manios E., Vemmou A., Rodríguez-Campello A., Cuadrado-Godia E., Roquer J., Arnao V., Caso V., Paciaroni M., DIez-Tejedor E., Fuentes B., Pérez Lucas J., Arauz A., Ameriso S.F., Pertierra L., Gómez-Schneider M., Hawkes M.A., Bandini F., Chavarria Cano B., Iglesias Mohedano A.M., Garciá Pastor A., Gil-Núñez A., Putaala J., Tatlisumak T., Barboza M.A., Athanasakis G., Gioulekas F., Makaritsis K., Papavasileiou V. (2017)
      Objective: To investigate whether the correlation of age and sex with the risk of recurrence and death seen in patients with previous ischemic stroke is also evident in patients with embolic stroke of undetermined source ...

    • Age-related cognitive decline and associations with sex, education and apolipoprotein E genotype across ethnocultural groups and geographic regions: a collaborative cohort study 

      Lipnicki D.M., Crawford J.D., Dutta R., Thalamuthu A., Kochan N.A., Andrews G., Lima-Costa M.F., Castro-Costa E., Brayne C., Matthews F.E., Stephan B.C.M., Lipton R.B., Katz M.J., Ritchie K., Scali J., Ancelin M.-L., Scarmeas N., Yannakoulia M., Dardiotis E., Lam L.C.W., Wong C.H.Y., Fung A.W.T., Guaita A., Vaccaro R., Davin A., Kim K.W., Han J.W., Kim T.H., Anstey K.J., Cherbuin N., Butterworth P., Scazufca M., Kumagai S., Chen S., Narazaki K., Ng T.P., Gao Q., Reppermund S., Brodaty H., Lobo A., Lopez-Anton R., Santabárbara J., Sachdev P.S., Cohort Studies of Memory in an International Consortium (COSMIC) (2017)
      Background: The prevalence of dementia varies around the world, potentially contributed to by international differences in rates of age-related cognitive decline. Our primary goal was to investigate how rates of age-related ...

    • Age-specific and lifetime behavior patterns in Drosophila melanogaster and the Mediterranean fruit fly, Ceratitis capitata 

      Carey, J. R.; Papadopoulos, N.; Kouloussis, N.; Katsoyannos, B.; Müller, H. G.; Wang, J. L.; Tseng, Y. K. (2006)
      Patterns of behavior were recorded every 10 min during a 2-h period each day from eclosion to death for individual Drosophila melanogaster (both sexes) and Ceratitis capitata (males-only) including walking, preening, ...

    • Aging Impairs Whole-Body Heat Loss in Women under Both Dry and Humid Heat Stress 

      Notley S.R., Poirier M.P., Hardcastle S.G., Flouris A.D., Boulay P., Sigal R.J., Kenny G.P. (2017)
      Purpose This study was designed to determine whether age-related impairments in whole-body heat loss, which are known to exist in dry heat, also occur in humid heat in women. Methods To evaluate this possibility, 10 young ...

    • Alanyl-glutamine restores tight junction organization after disruption by a conventional peritoneal dialysis fluid 

      Bartosova M., Herzog R., Ridinger D., Levai E., Jenei H., Zhang C., González Mateo G.T., Marinovic I., Hackert T., Bestvater F., Hausmann M., Cabrera M.L., Kratochwill K., Zarogiannis S.G., Schmitt C.P. (2020)
      Understanding and targeting the molecular basis of peritoneal solute and protein transport is essential to improve peritoneal dialysis (PD) efficacy and patient outcome. Supplementation of PD fluids (PDF) with alanyl-glutamine ...

    • Alterations in hearing function of patients with glucose disorders 

      Vergou Z., Paschou S.A., Bargiota A., Koukoulis G.N. (2019)
      Objective: To study the prevalence of hearing impairment in patients with various glucose disorders. Patients and methods: A total of 499 individuals were studied, 51 patients with type 1 (TIDM), 188 patients with type 2 ...

    • Alterations in xenobiotic-metabolizing enzyme activities across menstrual cycle in healthy volunteers 

      Asprodini E., Tsiokou V., Begas E., Kilindris T., Kouvaras E., Samara M., Messinis I. (2019)
      The purpose of the study was to determine whether the in vivo activities of drug-metabolizing enzymes CYP1A2 and CYP2A6, xanthine oxidase (XO), and N-acetyltransferase-2 (NAT2) vary across the menstrual cycle. Forty-two ...

    • Altered activity of xenobiotic detoxifying enzymes at menopause – A cross-sectional study 

      Tsiokou V., Kilindris T., Begas E., Kouvaras E., Kouretas D., Asprodini E.K. (2020)
      Xenobiotic metabolism at menopause is an under-investigated topic, albeit women spend one-third of their life in the postmenopausal period. The present study examined the effect of menopause on the in vivo activities of ...

    • Altitude-dependent prevalence of canine granulocytic anaplasmosis in Romania 

      Matei I.A., Ionicǎ A.M., D'amico G., Corduneanu A., Daskalaki A.A., Lefkaditis M., Mihalca A.D. (2017)
      Canine granulocytic anaplasmosis (CGA) is an important tick-borne disease with worldwide distribution. The importance of this disease resides in the ability of Anaplasma phagocytophilum to infect humans and several animal ...

    • aMAP risk score predicts hepatocellular carcinoma development in patients with chronic hepatitis 

      Fan R., Papatheodoridis G., Sun J., Innes H., Toyoda H., Xie Q., Mo S., Sypsa V., Guha I.N., Kumada T., Niu J., Dalekos G., Yasuda S., Barnes E., Lian J., Suri V., Idilman R., Barclay S.T., Dou X., Berg T., Hayes P.C., Flaherty J.F., Zhou Y., Zhang Z., Buti M., Hutchinson S.J., Guo Y., Calleja J.L., Lin L., Zhao L., Chen Y., Janssen H.L.A., Zhu C., Shi L., Tang X., Gaggar A., Wei L., Jia J., Irving W.L., Johnson P.J., Lampertico P., Hou J. (2020)
      Background & Aims: Hepatocellular carcinoma (HCC) is the leading cause of death in patients with chronic hepatitis. In this international collaboration, we sought to develop a global universal HCC risk score to predict the ...

    • Amiodarone plus Ranolazine for Conversion of Post-Cardiac Surgery Atrial Fibrillation: Enhanced Effectiveness in Reduced Versus Preserved Ejection Fraction Patients 

      Simopoulos V., Hevas A., Hatziefthimiou A., Dipla K., Skoularigis I., Tsilimingas N., Aidonidis I. (2018)
      Purpose: Ranolazine (RAN) added to amiodarone (AMIO) has been shown to accelerate termination of postoperative atrial fibrillation (POAF) following coronary artery bypass surgery in patients without heart failure (HF). ...

    • AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders 

      Salpietro V., Dixon C.L., Guo H., Bello O.D., Vandrovcova J., Efthymiou S., Maroofian R., Heimer G., Burglen L., Valence S., Torti E., Hacke M., Rankin J., Tariq H., Colin E., Procaccio V., Striano P., Mankad K., Lieb A., Chen S., Pisani L., Bettencourt C., Männikkö R., Manole A., Brusco A., Grosso E., Ferrero G.B., Armstrong-Moron J., Gueden S., Bar-Yosef O., Tzadok M., Monaghan K.G., Santiago-Sim T., Person R.E., Cho M.T., Willaert R., Yoo Y., Chae J.-H., Quan Y., Wu H., Wang T., Bernier R.A., Xia K., Blesson A., Jain M., Motazacker M.M., Jaeger B., Schneider A.L., Boysen K., Muir A.M., Myers C.T., Gavrilova R.H., Gunderson L., Schultz-Rogers L., Klee E.W., Dyment D., Osmond M., Parellada M., Llorente C., Gonzalez-Peñas J., Carracedo A., Van Haeringen A., Ruivenkamp C., Nava C., Heron D., Nardello R., Iacomino M., Minetti C., Skabar A., Fabretto A., Hanna M.G., Bugiardini E., Hostettler I., O’Callaghan B., Khan A., Cortese A., O’Connor E., Yau W.Y., Bourinaris T., Kaiyrzhanov R., Chelban V., Madej M., Diana M.C., Vari M.S., Pedemonte M., Bruno C., Balagura G., Scala M., Fiorillo C., Nobili L., Malintan N.T., Zanetti M.N., Krishnakumar S.S., Lignani G., Jepson J.E.C., Broda P., Baldassari S., Rossi P., Fruscione F., Madia F., Traverso M., De-Marco P., Pérez-Dueñas B., Munell F., Kriouile Y., El-Khorassani M., Karashova B., Avdjieva D., Kathom H., Tincheva R., Van-Maldergem L., Nachbauer W., Boesch S., Gagliano A., Amadori E., Goraya J.S., Sultan T., Kirmani S., Ibrahim S., Jan F., Mine J., Banu S., Veggiotti P., Zuccotti G.V., Ferrari M.D., Van Den Maagdenberg A.M.J., Verrotti A., Marseglia G.L., Savasta S., Soler M.A., Scuderi C., Borgione E., Chimenz R., Gitto E., Dipasquale V., Sallemi A., Fusco M., Cuppari C., Cutrupi M.C., Ruggieri M., Cama A., Capra V., Mencacci N.E., Boles R., Gupta N., Kabra M., Papacostas S., Zamba-Papanicolaou E., Dardiotis E., Maqbool S., Rana N., Atawneh O., Lim S.Y., Shaikh F., Koutsis G., Breza M., Coviello D.A., Dauvilliers Y.A., AlKhawaja I., AlKhawaja M., Al-Mutairi F., Stojkovic T., Ferrucci V., Zollo M., Alkuraya F.S., Kinali M., Sherifa H., Benrhouma H., Turki I.B.Y., Tazir M., Obeid M., Bakhtadze S., Saadi N.W., Zaki M.S., Triki C.C., Benfenati F., Gustincich S., Kara M., Belcastro V., Specchio N., Capovilla G., Karimiani E.G., Salih A.M., Okubadejo N.U., Ojo O.O., Oshinaike O.O., Oguntunde O., Wahab K., Bello A.H., Abubakar S., Obiabo Y., Nwazor E., Ekenze O., Williams U., Iyagba A., Taiwo L., Komolafe M., Senkevich K., Shashkin C., Zharkynbekova N., Koneyev K., Manizha G., Isrofilov M., Guliyeva U., Salayev K., Khachatryan S., Rossi S., Silvestri G., Haridy N., Ramenghi L.A., Xiromerisiou G., David E., Aguennouz M., Fidani L., Spanaki C., Tucci A., Raspall-Chaure M., Chez M., Tsai A., Fassi E., Shinawi M., Constantino J.N., De Zorzi R., Fortuna S., Kok F., Keren B., Bonneau D., Choi M., Benzeev B., Zara F., Mefford H.C., Scheffer I.E., Clayton-Smith J., Macaya A., Rothman J.E., Eichler E.E., Kullmann D.M., Houlden H., SYNAPS Study Group (2019)
      AMPA receptors (AMPARs) are tetrameric ligand-gated channels made up of combinations of GluA1-4 subunits encoded by GRIA1-4 genes. GluA2 has an especially important role because, following post-transcriptional editing at ...