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Anti-MOG Positive Bilateral Optic Neuritis and Brainstem Encephalitis Secondary to COVID-19 Infection: A Case Report
dc.creator | Tsouris Z., Provatas A., Bakirtzis C., Aloizou A.-M., Siokas V., Tsimourtou V., Grigoriadis N., Hadjigeorgiou G.M., Dardiotis E. | en |
dc.date.accessioned | 2023-01-31T10:20:02Z | |
dc.date.available | 2023-01-31T10:20:02Z | |
dc.date.issued | 2022 | |
dc.identifier | 10.3390/neurolint14040078 | |
dc.identifier.issn | 20358385 | |
dc.identifier.uri | http://hdl.handle.net/11615/80183 | |
dc.description.abstract | (1) Introduction: There have been numerous reports on the neuroinvasive competence of SARS-CoV-2. Here, we present a case with anti-MOG positive bilateral optic neuritis and brainstem encephalitis secondary to COVID-19 infection. Additionally, we present a review of the current literature regarding the manifestation of anti-MOG positive optic neuritis as well as anti-MOG positive encephalitis after COVID-19 infection. (2) Case Report: A 59-year-old female patient, with a recent history of COVID-19 infection, presented a progressive reduction of visual acuity and bilateral retrobulbar pain for the last 20 days. An ophthalmological examination revealed a decreased visual acuity (counting fingers) and a bilateral papilledema. An MRI scan of the brain revealed a mild thickening of the bilateral optic nerves and high-intensity lesions in the medial and right lateral pons. A high titer of IgG and IgM antibodies against SARS-CoV-2 in serum and antibodies against myelin oligodendrocyte glycoprotein (anti-MOG) in serum and CSF were revealed. The diagnosis of anti-MOG brainstem encephalitis and optic neuritis was set. (3) Conclusions: The history of COVID-19 infection should raise awareness about these autoimmune and infection-triggered diseases, such as anti-MOG antibody disease. © 2022 by the authors. | en |
dc.language.iso | en | en |
dc.source | Neurology International | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85144700621&doi=10.3390%2fneurolint14040078&partnerID=40&md5=30e49eb96a10cc60bc45c0cc44cde2ee | |
dc.subject | MDPI | en |
dc.title | Anti-MOG Positive Bilateral Optic Neuritis and Brainstem Encephalitis Secondary to COVID-19 Infection: A Case Report | en |
dc.type | journalArticle | en |
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