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Radiolabeled mAbs as Molecular Imaging and/or Therapy Agents Targeting PSMA

dc.creatorPsimadas D., Valotassiou V., Alexiou S., Tsougos I., Georgoulias P.en
dc.date.accessioned2023-01-31T09:50:51Z
dc.date.available2023-01-31T09:50:51Z
dc.date.issued2018
dc.identifier10.1080/07357907.2018.1430816
dc.identifier.issn07357907
dc.identifier.urihttp://hdl.handle.net/11615/78397
dc.description.abstractMolecular imaging and therapy is a rapidly evolving field in research and clinical medicine. The use of the exciting and attractive properties of radioisotopes for imaging and therapy has made Nuclear Medicine very significant when it comes to molecular imaging/therapy. Monoclonal Antibodies (mAbs) on the other hand are very important targeting biomolecules with high affinity that can “carry” the radioisotope of choice. Herein we make a brief overview of the radiolabeled mAbs that target prostate specific membrane antigen (PSMA) and their use in the management of patients with prostate cancer (PCa). © 2018 Taylor & Francis Group, LLC.en
dc.language.isoenen
dc.sourceCancer Investigationen
dc.source.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85044188246&doi=10.1080%2f07357907.2018.1430816&partnerID=40&md5=5f42f6b64d192be7fe497916b1f26f9f
dc.subjectantibodyen
dc.subjectcapromab pendetide in 111en
dc.subjectenzyme inhibitoren
dc.subjectmonoclonal antibodyen
dc.subjectmonoclonal antibody 3 A12en
dc.subjectmonoclonal antibody 3 E7en
dc.subjectmonoclonal antibody 3 F11en
dc.subjectmonoclonal antibody 3C6en
dc.subjectmonoclonal antibody J591en
dc.subjectnanobodyen
dc.subjectpeptideen
dc.subjectprostate specific membrane antigenen
dc.subjectradioisotopeen
dc.subjectradiopharmaceutical agenten
dc.subjectunclassified drugen
dc.subjectglutamate carboxypeptidase IIen
dc.subjectglutamate carboxypeptidase II, humanen
dc.subjectmembrane antigenen
dc.subjectmonoclonal antibodyen
dc.subjectradiopharmaceutical agenten
dc.subjecthumanen
dc.subjectisotope labelingen
dc.subjectmolecular imagingen
dc.subjectnonhumanen
dc.subjectpriority journalen
dc.subjectprostate canceren
dc.subjectradioisotope diagnosisen
dc.subjectradioisotope therapyen
dc.subjectReviewen
dc.subjectdiagnostic imagingen
dc.subjectimmunologyen
dc.subjectisotope labelingen
dc.subjectmaleen
dc.subjectmetabolismen
dc.subjectmolecular imagingen
dc.subjectproceduresen
dc.subjectprostate tumoren
dc.subjectAntibodies, Monoclonalen
dc.subjectAntigens, Surfaceen
dc.subjectGlutamate Carboxypeptidase IIen
dc.subjectHumansen
dc.subjectIsotope Labelingen
dc.subjectMaleen
dc.subjectMolecular Imagingen
dc.subjectProstatic Neoplasmsen
dc.subjectRadiopharmaceuticalsen
dc.subjectTaylor and Francis Ltden
dc.titleRadiolabeled mAbs as Molecular Imaging and/or Therapy Agents Targeting PSMAen
dc.typeotheren


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