Mostrar el registro sencillo del ítem
In early pubertal boys, testosterone and LH are associated with improved anti-oxidation during an aerobic exercise bout
dc.creator | Paltoglou G., Avloniti A., Chatzinikolaou A., Stefanaki C., Papagianni M., Papassotiriou I., Fatouros I.G., Chrousos G.P., Kanaka-Gantenbein C., Mastorakos G. | en |
dc.date.accessioned | 2023-01-31T09:41:24Z | |
dc.date.available | 2023-01-31T09:41:24Z | |
dc.date.issued | 2019 | |
dc.identifier | 10.1007/s12020-019-02037-1 | |
dc.identifier.issn | 1355008X | |
dc.identifier.uri | http://hdl.handle.net/11615/77441 | |
dc.description.abstract | Purpose: To investigate the association of the hypothalamic-pituitary-testicular (HPT) axis with pro- and anti- oxidation, in relation to puberty and obesity in boys, before and after an aerobic exercise bout. Methods: This is a cross-sectional human observational study of 92 healthy normal-weight, obese pre- and early- pubertal boys that underwent a blood sampling, before, and after an aerobic exercise bout at 70% VO2max, until exhaustion. LH, FSH, total testosterone (tT) and markers of pro- (TBARS and PCs) and anti- (GSH, GSSG, GPX, catalase, TAC) oxidation were measured. Results: Baseline LH, FSH, and tT concentrations were greater in early, than in pre- pubertal boys, independently of weight status. Post-exercise, LH concentrations decreased in early pubertal boys while FSH concentrations did not change in any of the studied groups. Baseline and post-exercise tT concentrations were lower in obese than in normal-weight early pubertal boys, while baseline and post-exercise LH and FSH concentrations did not differ between these groups. Post-exercise tT concentrations increased in early pubertal obese boys. Baseline LH, FSH and tT concentrations correlated positively with baseline anti-oxidation markers concentrations in pre-pubertal boys. Baseline tT concentrations correlated positively with the increase of TAC concentrations in early pubertal normal-weight boys. In all boys, baseline LH concentrations were the best positive predictors for the exercise-associated increase of TAC concentrations. Conclusions: It appears that the HPT axis maturation during puberty (in particular its LH and testosterone components) is positively associated with the increase of anti-oxidation during a bout of aerobic exercise. © 2019, Springer Science+Business Media, LLC, part of Springer Nature. | en |
dc.language.iso | en | en |
dc.source | Endocrine | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85074675969&doi=10.1007%2fs12020-019-02037-1&partnerID=40&md5=32f5d8625f9d49e9e48016dd465b528c | |
dc.subject | antioxidant | en |
dc.subject | carbonyl derivative | en |
dc.subject | catalase | en |
dc.subject | glutathione | en |
dc.subject | glutathione disulfide | en |
dc.subject | luteinizing hormone | en |
dc.subject | testosterone | en |
dc.subject | thiobarbituric acid reactive substance | en |
dc.subject | catalase | en |
dc.subject | follitropin | en |
dc.subject | glutathione | en |
dc.subject | luteinizing hormone | en |
dc.subject | testosterone | en |
dc.subject | thiobarbituric acid reactive substance | en |
dc.subject | adolescent | en |
dc.subject | adolescent obesity | en |
dc.subject | aerobic exercise | en |
dc.subject | Article | en |
dc.subject | child | en |
dc.subject | controlled study | en |
dc.subject | cross-sectional study | en |
dc.subject | endocrine function | en |
dc.subject | human | en |
dc.subject | hypothalamic pituitary testicular axis | en |
dc.subject | major clinical study | en |
dc.subject | male | en |
dc.subject | observational study | en |
dc.subject | oxidation | en |
dc.subject | priority journal | en |
dc.subject | puberty | en |
dc.subject | blood | en |
dc.subject | childhood obesity | en |
dc.subject | exercise | en |
dc.subject | metabolism | en |
dc.subject | oxidative stress | en |
dc.subject | physiology | en |
dc.subject | puberty | en |
dc.subject | Catalase | en |
dc.subject | Child | en |
dc.subject | Cross-Sectional Studies | en |
dc.subject | Exercise | en |
dc.subject | Follicle Stimulating Hormone | en |
dc.subject | Glutathione | en |
dc.subject | Humans | en |
dc.subject | Luteinizing Hormone | en |
dc.subject | Male | en |
dc.subject | Oxidative Stress | en |
dc.subject | Pediatric Obesity | en |
dc.subject | Puberty | en |
dc.subject | Testosterone | en |
dc.subject | Thiobarbituric Acid Reactive Substances | en |
dc.subject | Humana Press Inc. | en |
dc.title | In early pubertal boys, testosterone and LH are associated with improved anti-oxidation during an aerobic exercise bout | en |
dc.type | journalArticle | en |
Ficheros en el ítem
Ficheros | Tamaño | Formato | Ver |
---|---|---|---|
No hay ficheros asociados a este ítem. |