dc.creator | Nana P., Spanos K., Piffaretti G., Koncar I., Kouvelos G., Zlatanovic P., Tozzi M., Davidovic L., Giannoukas A. | en |
dc.date.accessioned | 2023-01-31T09:03:26Z | |
dc.date.available | 2023-01-31T09:03:26Z | |
dc.date.issued | 2020 | |
dc.identifier | 10.1007/s00268-020-05604-0 | |
dc.identifier.issn | 03642313 | |
dc.identifier.uri | http://hdl.handle.net/11615/76905 | |
dc.description.abstract | Background: Various techniques have been used for the execution of carotid endarterectomy; primary (PC), patch closure (CP) and eversion technique (ET).The superiority of any of them is still unproven. The aim of this study was to compare the long-term outcomes of each technique in terms of cerebrovascular event (CVE), restenosis, survival and major cardiac event (MACE). Methods: Between 2007 and 2018, a retrospective analysis of prospectively recorded data from three European tertiary centers was undertaken including 1.357 patients. Demographics, comorbidities and medical treatment were analyzed in relation to long-term outcomes. Freedom from CVE, restenosis (> 70%), survival and MACE were estimated with Kaplan–Meier analysis curve. Results: The mean age was 69.5 ± 8 (72% males;79% asymptomatic). 472 (35%) were treated with PC, 504 (37%) with CP and 381 (28%) with ET. Differences among groups were observed in age (P < 0.001), gender (P < 0.01), hypertension (P = 0.01), dyslipidemia (P < 0.001) and statin treatment (P < 0.001). The mean follow-up was 4.7 ± 3 years (median: 5 years). Seventy-three patients presented a CVE during 8 years of follow-up. The freedom from CVE including all techniques was 96% (SE 0.6%), 93% (SE 1%) and 89% (SE 1.6%), at 2, 5 and 8 years of follow-up, respectively, with no difference between groups (P.289). Freedom from restenosis was at 96% (SE 0.7%) and 89% (SE 5%) at 5 and 10 years, respectively, for all methods without differences. ET was associated with a higher mortality rate (P < 0.001) and MACE rate (P < 0.001). Conclusions: Excellent outcomes were achieved with all types of closure techniques with low rates of MACE and other adverse events during long-term follow-up after CEA. © 2020, Société Internationale de Chirurgie. | en |
dc.language.iso | en | en |
dc.source | World Journal of Surgery | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85085487939&doi=10.1007%2fs00268-020-05604-0&partnerID=40&md5=6ddc6b4545714acc41bbd1b440a664ce | |
dc.subject | adverse event | en |
dc.subject | aged | en |
dc.subject | cardiovascular disease | en |
dc.subject | carotid endarterectomy | en |
dc.subject | cerebrovascular accident | en |
dc.subject | clinical trial | en |
dc.subject | comparative study | en |
dc.subject | female | en |
dc.subject | human | en |
dc.subject | male | en |
dc.subject | middle aged | en |
dc.subject | multicenter study | en |
dc.subject | postoperative complication | en |
dc.subject | procedures | en |
dc.subject | retrospective study | en |
dc.subject | Aged | en |
dc.subject | Cardiovascular Diseases | en |
dc.subject | Endarterectomy, Carotid | en |
dc.subject | Female | en |
dc.subject | Humans | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | Postoperative Complications | en |
dc.subject | Retrospective Studies | en |
dc.subject | Stroke | en |
dc.subject | Springer | en |
dc.title | Long-term Durability and Safety of Carotid Endarterectomy Closure Techniques | en |
dc.type | journalArticle | en |