dc.creator | Magouliotis D.E., Tasiopoulou V.S., Athanassiadi K. | en |
dc.date.accessioned | 2023-01-31T08:55:45Z | |
dc.date.available | 2023-01-31T08:55:45Z | |
dc.date.issued | 2019 | |
dc.identifier | 10.1007/s11748-018-1027-6 | |
dc.identifier.issn | 18636705 | |
dc.identifier.uri | http://hdl.handle.net/11615/76090 | |
dc.description.abstract | Objective: We reviewed the available literature on patients with MPM undergoing either extrapleural pneumonectomy (EPP) or pleurectomy/decortication (P/D). Methods: Original research studies that evaluated long-term outcomes of P/D versus EPP were identified, from January 1990 to July 2018. The 30 and 90 days mortality, along with the 1-, 2-, 3-, 5-year survival, the median overall survival and the complications were calculated according to both a fixed and a random effect model. The Q statistics and I 2 statistic were used to test for heterogeneity among the studies. Results: Fifteen studies were included, incorporating a total of 1672 patients treated with EPP and 2236 treated with P/D. The 30-day mortality was significantly higher in the EPP group [OR 3.24 (95% CI 1.70, 6.20); p < 0.001]. The median overall survival was significantly increased in the P/D group [WMD − 4.20 (− 5.66, − 2.74); p < 0.001]. No significant differences were found regarding the 90-day mortality and the 1-, 2-, 3-, 5-year survival between the EPP and P/D groups. The incidence of postoperative atrial fibrillation, hemorrhage, empyema, bronchopleural fistula and air leak was significantly increased in the EPP group (p < 0.05). Conclusions: The present meta-analysis indicates that P/D is associated with enhanced outcomes regarding 30-day mortality, median overall survival, and complications. The P/D approach, should, therefore be preferred when technically feasible. However, the decision regarding the procedure of choice should be made on the basis of the disease status and the surgeon’s experience. Well-designed, randomized studies, comparing EPP to P/D, are necessary to further assess their clinical outcomes. © 2018, The Japanese Association for Thoracic Surgery. | en |
dc.language.iso | en | en |
dc.source | General Thoracic and Cardiovascular Surgery | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85055966985&doi=10.1007%2fs11748-018-1027-6&partnerID=40&md5=19141cc25494296a408143e39d79f429 | |
dc.subject | adult respiratory distress syndrome | en |
dc.subject | air leak | en |
dc.subject | Article | en |
dc.subject | atrial fibrillation | en |
dc.subject | bronchopleural fistula | en |
dc.subject | cancer research | en |
dc.subject | cancer surgery | en |
dc.subject | cancer survival | en |
dc.subject | decortication | en |
dc.subject | empyema | en |
dc.subject | extrapleural pneumonectomy | en |
dc.subject | human | en |
dc.subject | intermethod comparison | en |
dc.subject | lung embolism | en |
dc.subject | lung resection | en |
dc.subject | mesothelioma | en |
dc.subject | meta analysis | en |
dc.subject | overall survival | en |
dc.subject | pleurectomy | en |
dc.subject | postoperative complication | en |
dc.subject | postoperative hemorrhage | en |
dc.subject | surgical mortality | en |
dc.subject | treatment outcome | en |
dc.subject | lung tumor | en |
dc.subject | mesothelioma | en |
dc.subject | mortality | en |
dc.subject | pleura tumor | en |
dc.subject | procedures | en |
dc.subject | survival analysis | en |
dc.subject | thorax surgery | en |
dc.subject | Humans | en |
dc.subject | Lung Neoplasms | en |
dc.subject | Mesothelioma | en |
dc.subject | Pleural Neoplasms | en |
dc.subject | Postoperative Complications | en |
dc.subject | Survival Analysis | en |
dc.subject | Thoracic Surgical Procedures | en |
dc.subject | Springer Tokyo | en |
dc.title | Updated meta-analysis of survival after extrapleural pneumonectomy versus pleurectomy/decortication in mesothelioma | en |
dc.type | journalArticle | en |