Gesamter Bestand

Zur Kurzanzeige

Exhaled nitric oxide as a marker of chlorine exposure in young asthmatic swimmers

dc.creatorKotsiou O.S., Peletidou S., Vavougios G., Karetsi E., Stavrou V., Zakynthinos G., Gourgoulianis K.I., Daniil Z.en
dc.date.accessioned2023-01-31T08:44:54Z
dc.date.available2023-01-31T08:44:54Z
dc.date.issued2019
dc.identifier10.1016/j.anai.2019.06.008
dc.identifier.issn10811206
dc.identifier.urihttp://hdl.handle.net/11615/75230
dc.description.abstractBackground: Swimming is recommended for people with asthma. However, the inevitable exposure to chlorine and its disinfectant byproducts in indoor swimming pools could be responsible for bronchial inflammation and asthma development. Fractional exhaled nitric oxide (FeNO) is a noninvasive marker of airway inflammation that predicts asthma exacerbations. Objectives: To evaluate pretraining and posttraining FeNO levels in young swimmers with asthma attending an indoor chlorinated pool compared with a set of healthy swimmers and to examine the potential risk of exposure to chlorine as a factor associated with bronchial inflammation. Methods: A total of 146 children (8-18 years old) constantly attending an indoor chlorinated swimming pool were enrolled. Spirometry and FeNO measurements were performed 30 minutes after their arrival at the pool and immediately after exercise. Pre-exercise and postexercise spirometric and FeNO levels were assessed in a random subgroup of 14 swimmers (10 with asthma and 4 without) who performed cardiopulmonary exercise testing. Results: Asthma was detected in 23 swimmers. In swimmers with asthma, preswimming FeNO values were significantly elevated compared with swimmers without asthma and their FeNO values measured before cardiopulmonary exercise testing. Postexercise FeNO values were significantly decreased by approximately one-third in healthy children and children with asthma in all sporting backgrounds. However, postswimming FeNO values remained significantly higher in swimmers with asthma compared with those without asthma. Forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC), and FEV1/FVC ratio values showed no significant difference before and after 2 types of activity. Conclusion: Elevated FeNO levels before and after swimming were recorded in swimmers with asthma not observed in a different exercise field. The presence of chlorine in the indoor swimming pool seems to explain this finding. © 2019 American College of Allergy, Asthma & Immunologyen
dc.language.isoenen
dc.sourceAnnals of Allergy, Asthma and Immunologyen
dc.source.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85069928209&doi=10.1016%2fj.anai.2019.06.008&partnerID=40&md5=47ea698f2eaa8e34bcb8549715f9335c
dc.subjectchlorineen
dc.subjectnitric oxideen
dc.subjectadolescenten
dc.subjectadulten
dc.subjectArticleen
dc.subjectasthmaen
dc.subjectbicycle ergometryen
dc.subjectbreath analysisen
dc.subjectbronchitisen
dc.subjectcardiopulmonary exercise testen
dc.subjectchilden
dc.subjectchlorinationen
dc.subjectclinical articleen
dc.subjectcontrolled studyen
dc.subjectdisease associationen
dc.subjectdisease exacerbationen
dc.subjectexerciseen
dc.subjectexpired airen
dc.subjectexposureen
dc.subjectfemaleen
dc.subjectforced expiratory volumeen
dc.subjectforced vital capacityen
dc.subjectfractional exhaled nitric oxideen
dc.subjecthumanen
dc.subjectmaleen
dc.subjectpriority journalen
dc.subjectrespiratory tract inflammationen
dc.subjectspirometryen
dc.subjectswimmingen
dc.subjectswimming poolen
dc.subjectwater treatmenten
dc.subjectAmerican College of Allergy, Asthma and Immunologyen
dc.titleExhaled nitric oxide as a marker of chlorine exposure in young asthmatic swimmersen
dc.typejournalArticleen


Dateien zu dieser Ressource

DateienGrößeFormatAnzeige

Zu diesem Dokument gibt es keine Dateien.

Das Dokument erscheint in:

Zur Kurzanzeige