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Endocan and the respiratory system: A review
dc.creator | Kechagia M., Papassotiriou I., Gourgoulianis K.I. | en |
dc.date.accessioned | 2023-01-31T08:34:48Z | |
dc.date.available | 2023-01-31T08:34:48Z | |
dc.date.issued | 2016 | |
dc.identifier | 10.2147/COPD.S118692 | |
dc.identifier.issn | 11769106 | |
dc.identifier.uri | http://hdl.handle.net/11615/74729 | |
dc.description.abstract | Endocan, formerly called endothelial cell-specific molecule 1, is an endothelial cell-associated proteoglycan that is preferentially expressed by renal and pulmonary endothelium. It is upregulated by proangiogenic molecules as well as by pro-inflammatory cytokines, and since it reflects endothelial activation and dysfunction, it is regarded as a novel tissue and blood-based relevant biomarker. As such, it is increasingly being researched and evaluated in a wide spectrum of healthy and disease pathophysiological processes. Here, we review the present scientific knowledge on endocan, with emphasis on the evidence that underlines its possible clinical value as a prognostic marker in several malignant, inflammatory and obstructive disorders of the respiratory system. � 2016 Kechagia et al. | en |
dc.language.iso | en | en |
dc.source | International Journal of COPD | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85007508043&doi=10.2147%2fCOPD.S118692&partnerID=40&md5=b279bc626c538331d182dd851da4f76a | |
dc.subject | cytokine | en |
dc.subject | endocan | en |
dc.subject | proteoglycan | en |
dc.subject | unclassified drug | en |
dc.subject | biological marker | en |
dc.subject | ESM1 protein, human | en |
dc.subject | proteoglycan | en |
dc.subject | tumor protein | en |
dc.subject | acute lung injury | en |
dc.subject | adult respiratory distress syndrome | en |
dc.subject | airway obstruction | en |
dc.subject | cancer prognosis | en |
dc.subject | endothelial dysfunction | en |
dc.subject | endothelium cell | en |
dc.subject | human | en |
dc.subject | lower respiratory tract infection | en |
dc.subject | lung cancer | en |
dc.subject | pathophysiology | en |
dc.subject | pneumonia | en |
dc.subject | protein binding | en |
dc.subject | protein blood level | en |
dc.subject | protein expression | en |
dc.subject | protein protein interaction | en |
dc.subject | protein structure | en |
dc.subject | respiratory tract disease | en |
dc.subject | Review | en |
dc.subject | tumor invasion | en |
dc.subject | animal | en |
dc.subject | lung | en |
dc.subject | metabolism | en |
dc.subject | prognosis | en |
dc.subject | respiratory tract disease | en |
dc.subject | signal transduction | en |
dc.subject | vascularization | en |
dc.subject | Animals | en |
dc.subject | Biomarkers | en |
dc.subject | Endothelial Cells | en |
dc.subject | Humans | en |
dc.subject | Lung | en |
dc.subject | Neoplasm Proteins | en |
dc.subject | Prognosis | en |
dc.subject | Proteoglycans | en |
dc.subject | Respiratory Tract Diseases | en |
dc.subject | Signal Transduction | en |
dc.subject | Dove Medical Press Ltd. | en |
dc.title | Endocan and the respiratory system: A review | en |
dc.type | other | en |
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