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Statin loading in cardiovascular surgery: Never too early to treat
dc.creator | Katsiki N., Triposkiadis F., Giannoukas A.D., Mikhailidis D.P. | en |
dc.date.accessioned | 2023-01-31T08:33:48Z | |
dc.date.available | 2023-01-31T08:33:48Z | |
dc.date.issued | 2018 | |
dc.identifier | 10.1097/HCO.0000000000000519 | |
dc.identifier.issn | 02684705 | |
dc.identifier.uri | http://hdl.handle.net/11615/74641 | |
dc.description.abstract | Purpose of review The effects of statin loading before, during or after vascular interventions on cardiovascular and renal outcomes are discussed. Furthermore, the selection of optimal statin type and dose, according to current evidence or guidelines, is considered. The importance of treating statin intolerance and avoiding statin discontinuation is also discussed. Recent findings Statin loading has been shown to beneficially affect cardiovascular outcomes, total mortality and/or contrast-induced acute kidney injury, in patients undergoing vascular procedures such as percutaneous coronary intervention (PCI), coronary artery bypass grafting (CABG), carotid endarterectomy (CEA), carotid artery stenting, endovascular aneurysm repair, open abdominal aortic aneurysms (AAA) repair and lower extremities vascular interventions. High-dose statin pretreatment is recommended for PCI and CABG according to current guidelines. Statin discontinuation should be avoided during acute cardiovascular events and vascular interventions; adequate measures should be implemented to overcome statin intolerance. Summary Statin loading is an important clinical issue in patients with cardiac and noncardiac vascular diseases, including carotid artery disease, peripheral artery disease and AAA, undergoing vascular interventions. Cardiologists and vascular surgeons should be aware of current evidence and implement guidelines in relation to statin loading, discontinuation and intolerance. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved. | en |
dc.language.iso | en | en |
dc.source | Current Opinion in Cardiology | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85050387402&doi=10.1097%2fHCO.0000000000000519&partnerID=40&md5=54f5b861ffeb025b80fe6d9790cf649f | |
dc.subject | hydroxymethylglutaryl coenzyme A reductase inhibitor | en |
dc.subject | hydroxymethylglutaryl coenzyme A reductase inhibitor | en |
dc.subject | abdominal aortic aneurysm | en |
dc.subject | acute kidney failure | en |
dc.subject | cardiovascular surgery | en |
dc.subject | carotid artery stenting | en |
dc.subject | carotid endarterectomy | en |
dc.subject | coronary artery bypass graft | en |
dc.subject | drug megadose | en |
dc.subject | drug withdrawal | en |
dc.subject | endovascular aneurysm repair | en |
dc.subject | human | en |
dc.subject | open surgery | en |
dc.subject | percutaneous coronary intervention | en |
dc.subject | priority journal | en |
dc.subject | Review | en |
dc.subject | acute kidney failure | en |
dc.subject | chemically induced | en |
dc.subject | postoperative complication | en |
dc.subject | preoperative care | en |
dc.subject | Acute Kidney Injury | en |
dc.subject | Cardiovascular Surgical Procedures | en |
dc.subject | Humans | en |
dc.subject | Hydroxymethylglutaryl-CoA Reductase Inhibitors | en |
dc.subject | Postoperative Complications | en |
dc.subject | Preoperative Care | en |
dc.subject | Lippincott Williams and Wilkins | en |
dc.title | Statin loading in cardiovascular surgery: Never too early to treat | en |
dc.type | other | en |
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