Mostra i principali dati dell'item
A green extraction process for polyphenols from elderberry (Sambucus nigra) flowers using deep eutectic solvent and ultrasound-assisted pretreatment
dc.creator | Kaltsa O., Lakka A., Grigorakis S., Karageorgou I., Batra G., Bozinou E., Lalas S., Makris D.P. | en |
dc.date.accessioned | 2023-01-31T08:29:43Z | |
dc.date.available | 2023-01-31T08:29:43Z | |
dc.date.issued | 2020 | |
dc.identifier | 10.3390/molecules25040921 | |
dc.identifier.issn | 14203049 | |
dc.identifier.uri | http://hdl.handle.net/11615/74221 | |
dc.description.abstract | Sambucus nigra flowers, known as elderberry flowers (EBF), are a plant tissue rich in polyphenolic phytochemicals with important bioactivities. However, there are few studies dealing with the production of polyphenol-containing EBF extracts. The objective of the investigation presented herein was the development of a high-performance green extraction methodology, to generate EBF extracts enriched in polyphenolic substances, using an effcient deep eutectic solvent, combined with ultrasonication pretreatment. The DES was composed of L-lactic acid (hydrogen bond donor-HBD) and glycine (hydrogen bond acceptor-HBA) and, after an initial screening to properly regulate HBD/HBA ratio, the extraction was optimized by deploying response surface methodology. Under the optimized conditions, which were DES/water (85% w/v), liquid-to-solid ratio 60 mL g-1, and stirring speed 200 rounds per minute, the extraction yield in total polyphenols amounted to 121.24 ± 8.77 mg gallic acid equivalents per g dry matter. The integration of ultrasonication prior to the batch stirred-tank extraction boosted polyphenol recovery of up to 174.73 ± 2.62 mg gallic acid equivalents per g dry matter. Liquid chromatography-mass spectrometry analysis showed that the richest EBF extract obtained was dominated by rutin, a di-p-coumaroylquic acid and chlorogenic acid. © 2020 by the authors. | en |
dc.language.iso | en | en |
dc.source | Molecules | en |
dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85079881125&doi=10.3390%2fmolecules25040921&partnerID=40&md5=08ba4893c20a664dce90e797dab2e655 | |
dc.subject | polyphenol | en |
dc.subject | solvent | en |
dc.subject | chemistry | en |
dc.subject | flower | en |
dc.subject | green chemistry | en |
dc.subject | isolation and purification | en |
dc.subject | Sambucus | en |
dc.subject | ultrasound | en |
dc.subject | Flowers | en |
dc.subject | Green Chemistry Technology | en |
dc.subject | Polyphenols | en |
dc.subject | Sambucus | en |
dc.subject | Solvents | en |
dc.subject | Ultrasonic Waves | en |
dc.subject | MDPI AG | en |
dc.title | A green extraction process for polyphenols from elderberry (Sambucus nigra) flowers using deep eutectic solvent and ultrasound-assisted pretreatment | en |
dc.type | journalArticle | en |
Files in questo item
Files | Dimensione | Formato | Mostra |
---|---|---|---|
Nessun files in questo item. |