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Elevated inflammatory status and increased risk of chronic disease in chronological aging: Inflamm-aging or inflamm-inactivity?

dc.creatorFlynn M.G., Markofski M.M., Carrillo A.E.en
dc.date.accessioned2023-01-31T07:38:16Z
dc.date.available2023-01-31T07:38:16Z
dc.date.issued2019
dc.identifier10.14336/AD.2018.0326
dc.identifier.issn21525250
dc.identifier.urihttp://hdl.handle.net/11615/71646
dc.description.abstractAge-associated hyper-inflammation or “inflamm-aging” has been linked to the development of chronic diseases and characterized as an unavoidable aspect of aging. However, the inflamm-aging model does not adequately address the potential anti-inflammatory effects of exercise training and the potential for exercise to ameliorate several age-related diseases. In this brief review, we introduce a new paradigm—inflamm-inactivity—that describes a potent counter-measure to age-associated inflammatory illness. © 2018 Flynn MG et al.en
dc.language.isoenen
dc.sourceAging and Diseaseen
dc.source.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85066135816&doi=10.14336%2fAD.2018.0326&partnerID=40&md5=f27fae5f81bf4f61caa2b569e77eedfd
dc.subjectadiponectinen
dc.subjectC reactive proteinen
dc.subjectfluoxetineen
dc.subjectheat shock proteinen
dc.subjectimmunoglobulin enhancer binding proteinen
dc.subjectinterleukin 10en
dc.subjectinterleukin 6en
dc.subjectmitochondrial DNAen
dc.subjectmyeloperoxidaseen
dc.subjectnitric oxideen
dc.subjecttoll like receptor 4en
dc.subjecttransforming growth factor betaen
dc.subjecttumor necrosis factoren
dc.subjectagingen
dc.subjectantiinflammatory activityen
dc.subjectapoptosisen
dc.subjectbody compositionen
dc.subjectbody massen
dc.subjectcardiovascular diseaseen
dc.subjectchronic diseaseen
dc.subjectcognitionen
dc.subjectDNA damageen
dc.subjectexercise intensityen
dc.subjectglucose blood levelen
dc.subjecthomeostasis model assessmenten
dc.subjecthumanen
dc.subjectimmune responseen
dc.subjectinflammationen
dc.subjectinsulin resistanceen
dc.subjectlifestyle modificationen
dc.subjectmetabolic syndrome Xen
dc.subjectnon insulin dependent diabetes mellitusen
dc.subjectoxidative stressen
dc.subjectphysical activityen
dc.subjectphysical inactivityen
dc.subjectphysiologyen
dc.subjectresistance trainingen
dc.subjectReviewen
dc.subjectwound healingen
dc.subjectInternational Society on Aging and Diseaseen
dc.titleElevated inflammatory status and increased risk of chronic disease in chronological aging: Inflamm-aging or inflamm-inactivity?en
dc.typeotheren


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