Modulation of catalytic RNA biological activity by small molecule effectors

dc.creator	Vourekas, A.	en
dc.creator	Kalavrizioti, D.	en
dc.creator	Stathopoulos, C.	en
dc.creator	Drainas, D.	en
dc.date.accessioned	2015-11-23T10:54:03Z
dc.date.available	2015-11-23T10:54:03Z
dc.date.issued	2006
dc.identifier	10.2174/138955706778195199
dc.identifier.issn	1389-5575
dc.identifier.uri	http://hdl.handle.net/11615/34637
dc.description.abstract	Catalytic RNAs, known as ribozymes, act as true enzymes and are implicated in important biological processes, such as protein synthesis, mRNA splicing, transcriptional regulation and retroviral replication. Ribozymes are capable of serving as a new molecular target for a variety of drugs and as a reliable screening system for their biological activity.	en
dc.source	Mini-Reviews in Medicinal Chemistry	en
dc.source.uri	<Go to ISI>://WOS:000239732700002
dc.subject	ribozymes	en
dc.subject	RNase P	en
dc.subject	ribosome	en
dc.subject	drug target	en
dc.subject	aminoglycosides	en
dc.subject	macrolides	en
dc.subject	retinoids	en
dc.subject	calcipotriol	en
dc.subject	RIBONUCLEASE-P ACTIVITY	en
dc.subject	PEPTIDYL TRANSFERASE CENTER	en
dc.subject	LARGE	en
dc.subject	RIBOSOMAL-SUBUNIT	en
dc.subject	AMINOACYL-TRANSFER-RNA	en
dc.subject	AMINOGLYCOSIDE ANTIBIOTICS	en
dc.subject	HAMMERHEAD RIBOZYME	en
dc.subject	STRUCTURAL BASIS	en
dc.subject	CRYSTAL-STRUCTURE	en
dc.subject	PEPTIDYLTRANSFERASE INHIBITORS	en
dc.subject	BACTERIAL-RIBOSOMES	en
dc.subject	Chemistry, Medicinal	en
dc.title	Modulation of catalytic RNA biological activity by small molecule effectors	en
dc.type	journalArticle	en

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