Influence of Interleukin 1 alpha (IL-1 alpha), IL-4, and IL-6 Polymorphisms on Genetic Susceptibility to Chronic Osteomyelitis

dc.creator	Tsezou, A.	en
dc.creator	Poultsides, L.	en
dc.creator	Kostopoulou, F.	en
dc.creator	Zintzaras, E.	en
dc.creator	Satra, M.	en
dc.creator	Kitsiou-Tzeli, S.	en
dc.creator	Malizos, K. N.	en
dc.date.accessioned	2015-11-23T10:51:10Z
dc.date.available	2015-11-23T10:51:10Z
dc.date.issued	2008
dc.identifier	10.1128/cvi.00209-08
dc.identifier.issn	1556-6811
dc.identifier.uri	http://hdl.handle.net/11615/33854
dc.description.abstract	The association between cytokine gene polymorphisms and chronic osteomyelitis was investigated in order to determine whether genetic variability in cytokine genes predisposes to osteomyelitis susceptibility. Significant genotypic and allelic associations were observed between interleukin 1 alpha (IL-1 alpha) -889-C/T, IL-4 -1098-G/T and -590-C/T, and IL-6 -174-G/C polymorphisms and osteomyelitis in the Greek population, pointing towards their potential involvement in osteomyelitis pathogenesis.	en
dc.source	Clinical and Vaccine Immunology	en
dc.source.uri	<Go to ISI>://WOS:000261384800021
dc.subject	NECROSIS-FACTOR-ALPHA	en
dc.subject	OSTEOCLASTS	en
dc.subject	PROMOTER	en
dc.subject	Immunology	en
dc.subject	Infectious Diseases	en
dc.subject	Microbiology	en
dc.title	Influence of Interleukin 1 alpha (IL-1 alpha), IL-4, and IL-6 Polymorphisms on Genetic Susceptibility to Chronic Osteomyelitis	en
dc.type	journalArticle	en

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