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Outbreak caused by a multidrug-resistant Klebsiella pneumoniae clone carrying bla(VIM-12) in a university hospital

dc.creatorTokatlidou, D.en
dc.creatorTsivitanidou, M.en
dc.creatorPournaras, S.en
dc.creatorIkonomidis, A.en
dc.creatorTsakris, A.en
dc.creatorSofianou, D.en
dc.date.accessioned2015-11-23T10:50:04Z
dc.date.available2015-11-23T10:50:04Z
dc.date.issued2008
dc.identifier10.1128/jcm.01573-07
dc.identifier.issn0095-1137
dc.identifier.urihttp://hdl.handle.net/11615/33670
dc.description.abstractFrom November 2006 to April 2007, nine nonrepetitive isolates of Klebsiella pneumoniae with reduced susceptibility or resistance to carbapenems were recovered from clinical specimens from separate patients hospitalized in a tertiary care hospital. The imipenem-EDTA synergy test was positive for all isolates. PCR, sequencing, and transferability experiments revealed the novel bla(VIM-12), metallo-beta-lactamase gene, which was plasmid mediated and located in a class 1 integron. Pulsed-field gel electrophoresis demonstrated a single macrorestriction pattern, indicating the clonal spread of VIM-12-producing K. pneumoniae.en
dc.sourceJournal of Clinical Microbiologyen
dc.source.uri<Go to ISI>://WOS:000254059800028
dc.subjectMETALLO-BETA-LACTAMASEen
dc.subjectAERUGINOSA CLINICAL ISOLATEen
dc.subjectPSEUDOMONAS-AERUGINOSAen
dc.subjectACINETOBACTER-BAUMANNIIen
dc.subjectESCHERICHIA-COLIen
dc.subjectVIM-1/VIM-2 HYBRIDen
dc.subjectGREEK HOSPITALSen
dc.subjectGENEen
dc.subjectINTEGRONen
dc.subjectPLASMIDen
dc.subjectMicrobiologyen
dc.titleOutbreak caused by a multidrug-resistant Klebsiella pneumoniae clone carrying bla(VIM-12) in a university hospitalen
dc.typejournalArticleen


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