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Chemokine CXCL-1 Expression in the Subretinal Fluid during Rhegmatogenous Retinal Detachment
dc.creator | Symeonidis, C. | en |
dc.creator | Androudi, S. | en |
dc.creator | Rotsos, T. | en |
dc.creator | Moschos, M. M. | en |
dc.creator | Souliou, E. | en |
dc.creator | Dimitrakos, S. A. | en |
dc.creator | Diza, E. | en |
dc.date.accessioned | 2015-11-23T10:49:09Z | |
dc.date.available | 2015-11-23T10:49:09Z | |
dc.date.issued | 2014 | |
dc.identifier | 10.3109/09273948.2013.863942 | |
dc.identifier.issn | 0927-3948 | |
dc.identifier.uri | http://hdl.handle.net/11615/33490 | |
dc.description.abstract | Purpose: To investigate the expression of chemokine CXCL-1 in the subretinal fluid (SRF) during rhegmatogenous retinal detachment (RRD) and identify potential correlations with number of quadrants involved and duration of the detachment. Methods and Results: Inclusion criteria were patients aged 18 years or older and primary RRD possibly complicated by proliferative vitreoretinopathy (PVR). CXCL-1 levels were measured in 36 SRF samples from 36 RRD patients. Mean CXCL-1 levels (102 +/- 37 pg/mL) were significantly higher (p = 0.050) compared to controls. CXCL-1 levels correlated significantly with age (p = 0.001) and RRD duration (p = 0.002). Maximum CXCL-1 levels coincided with total RRD, 29- to 60-day duration and PVR grade C. Conclusions: The findings of this study may contribute to increased understanding regarding the role of CXCL-1 during the onset and progression of the wound healing process in the context of RRD and PVR. | en |
dc.source.uri | <Go to ISI>://WOS:000345209300006 | |
dc.subject | CXCL-1 | en |
dc.subject | GRO-alpha | en |
dc.subject | proliferative vitreoretinopathy | en |
dc.subject | rhegmatogenous | en |
dc.subject | retinal detachment | en |
dc.subject | subretinal fluid | en |
dc.subject | SPINAL-CORD-INJURY | en |
dc.subject | PROLIFERATIVE VITREORETINOPATHY | en |
dc.subject | GRO-ALPHA | en |
dc.subject | INTERLEUKIN-6 | en |
dc.subject | EXTENT | en |
dc.subject | PVR | en |
dc.subject | Ophthalmology | en |
dc.title | Chemokine CXCL-1 Expression in the Subretinal Fluid during Rhegmatogenous Retinal Detachment | en |
dc.type | journalArticle | en |
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