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dc.creatorPsimadas, D.en
dc.creatorMessini-Nikolaki, N.en
dc.creatorZafiropoulou, M.en
dc.creatorFortos, A.en
dc.creatorTsilimigaki, S.en
dc.creatorPiperakis, S. M.en
dc.date.accessioned2015-11-23T10:46:14Z
dc.date.available2015-11-23T10:46:14Z
dc.date.issued2004
dc.identifier10.1016/j.canlet.2003.09.022
dc.identifier.issn0304-3835
dc.identifier.urihttp://hdl.handle.net/11615/32537
dc.description.abstractIn the present study we examined schizophrenic patients' lymphocytes sensitivity to the effects of external factors, such as hydrogen peroxide and gamma-irradiation and also their repair efficiency with the comet assay. Our results did no show any difference in basal levels of DNA damage between schizophrenic and normal populations. The slightly increased sensitivity of the schizophrenic population to the externally induced DNA damage compared to controls was not statistically significant. Also the small reduction in the DNA repair efficiency in schizophrenics in comparison to normal population was found to be not statistically significant. Finally, patients with heritable predisposition to schizophrenia did not show any difference in their response from the other schizophrenics. (C) 2003 Elsevier Ireland Ltd. All rights reserved.en
dc.sourceCancer Lettersen
dc.source.uri<Go to ISI>://WOS:000188975900005
dc.subjectschizophreniaen
dc.subjectcomet assayen
dc.subjectDNA damageen
dc.subjecthumansen
dc.subjectCOMET ASSAYen
dc.subjectCANCERen
dc.subjectOncologyen
dc.titleDNA damage and repair efficiency in lymphocytes from schizophrenic patientsen
dc.typejournalArticleen


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