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dc.creatorPournaras, S.en
dc.creatorTsakris, A.en
dc.creatorIkonomidis, A.en
dc.creatorMarkogiannakis, A.en
dc.creatorKristo, I.en
dc.creatorManiatis, A. N.en
dc.date.accessioned2015-11-23T10:46:06Z
dc.date.available2015-11-23T10:46:06Z
dc.date.issued2006
dc.identifier10.1080/00365540500322361
dc.identifier.issn0036-5548
dc.identifier.urihttp://hdl.handle.net/11615/32476
dc.description.abstractA highly cefotaxime- and cefepime-resistant but ceftazidime-sensitive Escherichia coli isolate was recovered from a community-acquired urinary infection of a Greek patient. Susceptibility testing, transfer assays, plasmid analysis as well as PCR and sequencing techniques were used to investigate the underlying mechanism of resistance. The isolate carried a new variant of the bla(CTX-M-3) gene that possessed a T instead of A at nt position 663. Cefotaxime resistance was transferable and carried on a 60 kb plasmid. The bla(CTX-M-3) variant was located downstream of an ISEcp1B element. The emergence of this new derivative indicates further evolution of the worldwide-distributed bla(CTX-M-3) gene.en
dc.source.uri<Go to ISI>://WOS:000235553800012
dc.subjectCTX-M ENZYMESen
dc.subjectFAMILY ENTEROBACTERIACEAEen
dc.subjectMOLECULAR EPIDEMIOLOGYen
dc.subjectKLEBSIELLA-PNEUMONIAEen
dc.subjectCTX-M-3en
dc.subjectSPREADen
dc.subjectGREECEen
dc.subjectPOLANDen
dc.subjectDISSEMINATIONen
dc.subjectHOSPITALSen
dc.subjectInfectious Diseasesen
dc.titleDetection of a novel variant bla(CTX-M-3) extended spectrum beta-lactamase gene in a community-acquired Escherichia coli isolateen
dc.typejournalArticleen


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