Εμφάνιση απλής εγγραφής

dc.creatorPitsikas, N.en
dc.creatorSakellaridis, N.en
dc.date.accessioned2015-11-23T10:45:43Z
dc.date.available2015-11-23T10:45:43Z
dc.date.issued2006
dc.identifier10.1016/j.bbr.2006.06.005
dc.identifier.issn1664328
dc.identifier.urihttp://hdl.handle.net/11615/32311
dc.description.abstractThe effects of extracts of Crocus sativus L. (CSE), on memory were investigated in the rat by using the object recognition and the step-through passive avoidance task. In the first study, post-training administration of CSE (30 and 60 g/kg) successfully counteracted extinction of recognition memory in the normal rat, suggesting that CSE modulates storage and/or retrieval of information. In a subsequent study, pre-training treatment with CSE (30 and 60 mg/kg) significantly antagonized the scopolamine (0.75 mg/kg)-induced performance deficits in the step-through passive avoidance test. These results support and extend prior findings about the implication of CSE in learning and memory mechanisms. © 2006 Elsevier B.V. All rights reserved.en
dc.source.urihttp://www.scopus.com/inward/record.url?eid=2-s2.0-33750024445&partnerID=40&md5=69891a68c796c256db1d68d5c325afe5
dc.subjectCrocus sativus L.en
dc.subjectMemoryen
dc.subjectObject recognitionen
dc.subjectPassive avoidanceen
dc.subjectRaten
dc.subjectScopolamineen
dc.subjectCrocus sativus extracten
dc.subjectanimal behavioren
dc.subjectanimal experimenten
dc.subjectarticleen
dc.subjectbrain protectionen
dc.subjectcontrolled studyen
dc.subjectCrocusen
dc.subjectdrug efficacyen
dc.subjectexploratory behavioren
dc.subjectinformation retrievalen
dc.subjectlearningen
dc.subjectmaleen
dc.subjectmedical assessmenten
dc.subjectmemory consolidationen
dc.subjectmemory disorderen
dc.subjectneuromodulationen
dc.subjectnonhumanen
dc.subjectobject relationen
dc.subjectpriority journalen
dc.subjectrecallen
dc.subjectrecognitionen
dc.subjectreinforcementen
dc.subjecttask performanceen
dc.subjectAnimalsen
dc.subjectAvoidance Learningen
dc.subjectDose-Response Relationship, Drugen
dc.subjectExtinction, Psychologicalen
dc.subjectFlowersen
dc.subjectNootropic Agentsen
dc.subjectPlant Extractsen
dc.subjectRandom Allocationen
dc.subjectRatsen
dc.subjectRats, Wistaren
dc.subjectReaction Timeen
dc.subjectRecognition (Psychology)en
dc.titleCrocus sativus L. extracts antagonize memory impairments in different behavioural tasks in the raten
dc.typejournalArticleen


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