dc.creator | Pitsikas, N. | en |
dc.creator | Sakellaridis, N. | en |
dc.date.accessioned | 2015-11-23T10:45:43Z | |
dc.date.available | 2015-11-23T10:45:43Z | |
dc.date.issued | 2006 | |
dc.identifier | 10.1016/j.bbr.2006.06.005 | |
dc.identifier.issn | 1664328 | |
dc.identifier.uri | http://hdl.handle.net/11615/32311 | |
dc.description.abstract | The effects of extracts of Crocus sativus L. (CSE), on memory were investigated in the rat by using the object recognition and the step-through passive avoidance task. In the first study, post-training administration of CSE (30 and 60 g/kg) successfully counteracted extinction of recognition memory in the normal rat, suggesting that CSE modulates storage and/or retrieval of information. In a subsequent study, pre-training treatment with CSE (30 and 60 mg/kg) significantly antagonized the scopolamine (0.75 mg/kg)-induced performance deficits in the step-through passive avoidance test. These results support and extend prior findings about the implication of CSE in learning and memory mechanisms. © 2006 Elsevier B.V. All rights reserved. | en |
dc.source.uri | http://www.scopus.com/inward/record.url?eid=2-s2.0-33750024445&partnerID=40&md5=69891a68c796c256db1d68d5c325afe5 | |
dc.subject | Crocus sativus L. | en |
dc.subject | Memory | en |
dc.subject | Object recognition | en |
dc.subject | Passive avoidance | en |
dc.subject | Rat | en |
dc.subject | Scopolamine | en |
dc.subject | Crocus sativus extract | en |
dc.subject | animal behavior | en |
dc.subject | animal experiment | en |
dc.subject | article | en |
dc.subject | brain protection | en |
dc.subject | controlled study | en |
dc.subject | Crocus | en |
dc.subject | drug efficacy | en |
dc.subject | exploratory behavior | en |
dc.subject | information retrieval | en |
dc.subject | learning | en |
dc.subject | male | en |
dc.subject | medical assessment | en |
dc.subject | memory consolidation | en |
dc.subject | memory disorder | en |
dc.subject | neuromodulation | en |
dc.subject | nonhuman | en |
dc.subject | object relation | en |
dc.subject | priority journal | en |
dc.subject | recall | en |
dc.subject | recognition | en |
dc.subject | reinforcement | en |
dc.subject | task performance | en |
dc.subject | Animals | en |
dc.subject | Avoidance Learning | en |
dc.subject | Dose-Response Relationship, Drug | en |
dc.subject | Extinction, Psychological | en |
dc.subject | Flowers | en |
dc.subject | Nootropic Agents | en |
dc.subject | Plant Extracts | en |
dc.subject | Random Allocation | en |
dc.subject | Rats | en |
dc.subject | Rats, Wistar | en |
dc.subject | Reaction Time | en |
dc.subject | Recognition (Psychology) | en |
dc.title | Crocus sativus L. extracts antagonize memory impairments in different behavioural tasks in the rat | en |
dc.type | journalArticle | en |