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Clonal dissemination of mupirocin-resistant staphylococci in Greek hospitals
dc.creator | Petinaki, E. | en |
dc.creator | Spiliopoulou, I. | en |
dc.creator | Kontos, F. | en |
dc.creator | Maniati, M. | en |
dc.creator | Bersos, Z. | en |
dc.creator | Stakias, N. | en |
dc.creator | Malamou-Lada, H. | en |
dc.creator | Koutsia-Carouzou, C. | en |
dc.creator | Maniatis, A. N. | en |
dc.date.accessioned | 2015-11-23T10:45:26Z | |
dc.date.available | 2015-11-23T10:45:26Z | |
dc.date.issued | 2004 | |
dc.identifier | 10.1093/jac/dkh028 | |
dc.identifier.issn | 0305-7453 | |
dc.identifier.uri | http://hdl.handle.net/11615/32185 | |
dc.description.abstract | Objectives: To determine the rates of mupirocin resistance in staphylococci during a 4 year period (1999-2002) in Greece. Materials: A total of 1200 Staphylococcus aureus and 2760 coagulase-negative staphylococci (CoNS), consecutively collected from four Greek hospitals located in different geographical areas, were tested for susceptibility to mupirocin using the Etest and a reference agar dilution method. Results: Twenty-four S. aureus (2%) and 532 CoNS (19.2%) were found to be mupirocin-resistant during the study period. High-level mupirocin resistance was detected in 20 S. aureus (1.6%) and in 440 CoNS (15.9%), respectively. No variations in the rates of mupirocin-resistant S. aureus in relation to the year of collection were observed. In contrast, the rate of mupirocin-resistant CoNS increased dramatically from 9% in 1999, to 14% in 2000, 20% in 2001 and reached 33% in 2002. PFGE analysis revealed the presence of one main clone (A) among mupirocin-resistant S. aureus and two main clones (i and a) among Staphylococcus epidermidis isolates. Conclusions: In Greece, the rate of mupirocin-resistant S. aureus has remained low and steady since 1999. The high rate of mupirocin-resistant CoNS (33%) in 2002 was due mainly to clonal dissemination of epidemic hospital clones. | en |
dc.source | Journal of Antimicrobial Chemotherapy | en |
dc.source.uri | <Go to ISI>://WOS:000187462800017 | |
dc.subject | Staphylococcus aureus | en |
dc.subject | Staphylococcus epidermidis | en |
dc.subject | mupirocin resistance | en |
dc.subject | epidemic clones | en |
dc.subject | Greece | en |
dc.subject | AUREUS | en |
dc.subject | Infectious Diseases | en |
dc.subject | Microbiology | en |
dc.subject | Pharmacology & Pharmacy | en |
dc.title | Clonal dissemination of mupirocin-resistant staphylococci in Greek hospitals | en |
dc.type | journalArticle | en |
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