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Circulating endothelin-3 and prolactin concentrations in healthy lactating women during the early puerperium
dc.creator | Malamitsi-Puchner, A. | en |
dc.creator | Messinis, I. E. | en |
dc.creator | Sakellariou, V. | en |
dc.creator | Economou, E. | en |
dc.creator | Michalas, S. | en |
dc.date.accessioned | 2015-11-23T10:38:29Z | |
dc.date.available | 2015-11-23T10:38:29Z | |
dc.date.issued | 1998 | |
dc.identifier | 10.1530/eje.0.1380181 | |
dc.identifier.issn | 0804-4643 | |
dc.identifier.uri | http://hdl.handle.net/11615/30540 | |
dc.description.abstract | Objective: To study the association between the circulating concentrations of endothelin-3 and prolactin in the early puerperium. Design: Prospective clinical study, including twenty-five healthy puerperal women breast-feeding their healthy full-term infants. Methods: Venous blood was drawn on day 1 and 4 post partum, and plasma endothelin-3 and serum prolactin were determined. Results: Circulating endothelin-3 and prolactin levels on day 4 did not differ significantly from the corresponding levels on day 1. However, a significant negative correlation was found on day 4 between endothelin-3 and prolactin Values (r = -0.688, P < 0.001) and an even stronger negative association existed between the net change in endothelin-3 from days 1 to 4 and the corresponding change in prolactin values (r = -0.732, P < 0.001). Conclusions: On the fourth day post partum, lactating healthy women show negative correlation between circulating endothelin-3 and prolactin levels. Whether this indicates a role for endothelin-3 in the control of prolactin secretion in the post partum period remains to be clarified. | en |
dc.source | European Journal of Endocrinology | en |
dc.source.uri | <Go to ISI>://WOS:000072196400011 | |
dc.subject | LUTEINIZING-HORMONE | en |
dc.subject | ANTERIOR-PITUITARY | en |
dc.subject | SECRETION | en |
dc.subject | CELLS | en |
dc.subject | RELEASE | en |
dc.subject | BRAIN | en |
dc.subject | GONADOTROPHS | en |
dc.subject | RECEPTORS | en |
dc.subject | GLAND | en |
dc.subject | BASAL | en |
dc.subject | Endocrinology & Metabolism | en |
dc.title | Circulating endothelin-3 and prolactin concentrations in healthy lactating women during the early puerperium | en |
dc.type | journalArticle | en |
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