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Uncommon leg ulcers in the lower extremity
dc.creator | Labropoulos, N. | en |
dc.creator | Manalo, D. | en |
dc.creator | Patel, N. P. | en |
dc.creator | Tiongson, J. | en |
dc.creator | Pryor, L. | en |
dc.creator | Giannoukas, A. D. | en |
dc.date.accessioned | 2015-11-23T10:37:22Z | |
dc.date.available | 2015-11-23T10:37:22Z | |
dc.date.issued | 2007 | |
dc.identifier | 10.1016/j.jvs.2006.11.012 | |
dc.identifier.issn | 7415214 | |
dc.identifier.uri | http://hdl.handle.net/11615/30140 | |
dc.description.abstract | Objective: To determine the prevalence of uncommon ulcers, unrelated to venous or arterial etiology, in patients presenting to vascular clinics. Methods: This was a multicenter prospective study of consecutive patients presenting with lower extremity ulceration. The settings were university hospital outpatient centers and venous clinics. A total of 799 limbs in 710 patients with leg ulcers were evaluated. Patients with venous ulcer disease and with evidence of arterial disease with an ankle-brachial index less than 0.7 were excluded from the study. Out of 710 patients, 17 patients with a total of 21 limbs fit the criteria for inclusion. All limbs included in this study underwent physical examination, ankle-brachial index measurements, duplex ultrasonography, and skin biopsies. Results: The mean age of patients with uncommon ulcers was 65.6 years, and the mean duration was 5.5 years. A total of 2.1% of all leg ulcers seen were due to uncommon etiology unrelated to venous or arterial pathology. Most of these ulcers were located in the medial lower calf (n = 19). In six patients with ulcers, the histology did not reveal any specific cause; five had a neoplasia, three had chronic inflammation, two had sickle cell disease, two had vasculitis, one had rheumatoid arthritis, one had pyoderma gangrenosum, and one had ulcer due to hydroxyurea. Conclusions: The prevalence of leg ulcers unrelated to arterial and venous disease that presented with signs and symptoms of chronic venous disease was 2.1%. Their etiology is variable, most often including vasculitis, neoplasia, metabolic disorders, infection, and other rare causes. Early identification of uncommon ulcers may facilitate timely and appropriate management. © 2007 The Society for Vascular Surgery. | en |
dc.source.uri | http://www.scopus.com/inward/record.url?eid=2-s2.0-33847169403&partnerID=40&md5=6c12c11ba209120bd83ac4a9425ca887 | |
dc.subject | antibiotic agent | en |
dc.subject | hydroxyurea | en |
dc.subject | adult | en |
dc.subject | aged | en |
dc.subject | ankle brachial index | en |
dc.subject | artery disease | en |
dc.subject | article | en |
dc.subject | chronic inflammation | en |
dc.subject | clinical trial | en |
dc.subject | Doppler echography | en |
dc.subject | female | en |
dc.subject | health center | en |
dc.subject | human | en |
dc.subject | leg ulcer | en |
dc.subject | major clinical study | en |
dc.subject | male | en |
dc.subject | metabolic disorder | en |
dc.subject | multicenter study | en |
dc.subject | neoplasm | en |
dc.subject | outpatient department | en |
dc.subject | physical examination | en |
dc.subject | prevalence | en |
dc.subject | priority journal | en |
dc.subject | prospective study | en |
dc.subject | pyoderma gangrenosum | en |
dc.subject | rheumatoid arthritis | en |
dc.subject | sickle cell anemia | en |
dc.subject | skin biopsy | en |
dc.subject | university hospital | en |
dc.subject | vasculitis | en |
dc.subject | vein disease | en |
dc.subject | Adolescent | en |
dc.subject | Ambulatory Care Facilities | en |
dc.subject | Blood Pressure | en |
dc.subject | Brazil | en |
dc.subject | Europe | en |
dc.subject | Hospitals, University | en |
dc.subject | Humans | en |
dc.subject | Lower Extremity | en |
dc.subject | Middle Aged | en |
dc.subject | Prospective Studies | en |
dc.subject | Time Factors | en |
dc.subject | Ultrasonography, Doppler, Duplex | en |
dc.subject | United States | en |
dc.title | Uncommon leg ulcers in the lower extremity | en |
dc.type | journalArticle | en |
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