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Effect of prolonged aflatoxin B-1 administration on blood serum oestradiol-17 beta and progesterone concentrations of goats during the anoestrus period
dc.creator | Kourousekos, G. D. | en |
dc.creator | Theodosiadou, E. K. | en |
dc.creator | Lymberopoulos, A. G. | en |
dc.creator | Belibasaki, S. | en |
dc.creator | Boscos, C. | en |
dc.date.accessioned | 2015-11-23T10:36:24Z | |
dc.date.available | 2015-11-23T10:36:24Z | |
dc.date.issued | 2015 | |
dc.identifier | 10.17221/8130-cjas | |
dc.identifier.issn | 1212-1819 | |
dc.identifier.uri | http://hdl.handle.net/11615/29872 | |
dc.description.abstract | The effect of prolonged aflatoxin B-1 (AFB(1)) administration on blood serum oestradiol-17 beta and progesterone concentrations in goats during the anoestrus period was investigated. Thirty Greek indigenous goats were used; 10 goats received, per os, 50 mu g (treated group T50) and 10 goats received 100 mu g (treated group T100) AFB(1)/day/head, respectively, for 31 days, while 10 goats served as controls (C). Blood samples were collected from each goat twice a week to determine serum oestradiol-17 beta and progesterone concentrations by radioimmunoassay. Multiple linear regression analysis revealed a significant (P < 0.05) positive dependence of blood serum oestradiol-17 beta concentration over group (C = 0, T50 = 50, T100 = 100), in a dose-dependent manner, and a significant (P < 0.05) negative dependence over time (0-31 days, from the onset to the end of AFB(1) administration). Linear regression analysis revealed a significant (P < 0.05) positive dependence of blood serum progesterone concentration over group (C = 0, T50 = 50, T100 = 100), in a dose-dependent manner. Pearson's correlation coefficient revealed a significant (P < 0.05) positive correlation between blood serum oestradiol-17 beta and progesterone concentration, but only in the goats of the control group. In conclusion, the prolonged administration of 100 or even of 50 mu g AFB(1)/day/head during the anoestrus period, increased blood serum oestradiol-17 beta and progesterone concentrations of goats, in a dose-dependent manner, and in the treated groups disturbed the positive correlation between oestradiol-17 beta and progesterone concentration shown in the goats of the control group. | en |
dc.source.uri | <Go to ISI>://WOS:000354765900003 | |
dc.subject | aflatoxins | en |
dc.subject | mycotoxins | en |
dc.subject | ovarian steroids | en |
dc.subject | small ruminants | en |
dc.subject | anoestrus | en |
dc.subject | BREAST-MILK | en |
dc.subject | EWES | en |
dc.subject | ESTROGEN | en |
dc.subject | HORMONE | en |
dc.subject | TESTOSTERONE | en |
dc.subject | REPRODUCTION | en |
dc.subject | SPERMATOZOA | en |
dc.subject | BINDING | en |
dc.subject | PLASMA | en |
dc.subject | WOMEN | en |
dc.subject | Agriculture, Dairy & Animal Science | en |
dc.title | Effect of prolonged aflatoxin B-1 administration on blood serum oestradiol-17 beta and progesterone concentrations of goats during the anoestrus period | en |
dc.type | journalArticle | en |
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