dc.creator | Kostadima, E. | en |
dc.creator | Kaditis, A. G. | en |
dc.creator | Alexopoulos, E. I. | en |
dc.creator | Zakynthinos, E. | en |
dc.creator | Sfyras, D. | en |
dc.date.accessioned | 2015-11-23T10:35:42Z | |
dc.date.available | 2015-11-23T10:35:42Z | |
dc.date.issued | 2005 | |
dc.identifier | 10.1183/09031936.05.00096104 | |
dc.identifier.issn | 9031936 | |
dc.identifier.uri | http://hdl.handle.net/11615/29667 | |
dc.description.abstract | Presence of a nasogastric tube is a risk factor for the development of ventilator-associated pneumonia (VAP). Alternatively, gastrostomy can be used for administration of enteral feedings. To determine whether early performance of gastrostomy affects frequency of VAP, a randomised, controlled study was carried out in patients mechanically ventilated for stroke or head injury. In the gastrostomy group, patients underwent the procedure within 24 h of intubation. A nasogastric tube was inserted in controls. Individual subjects were studied for 3 weeks. In total, 20 subjects (mean age 48 ± 15.2 yrs) were allocated to the gastrostomy group, and 21 to the control group (46.6 ± 15.4 yrs). Of these groups, two (10%) and eight (38.1%) developed VAP, respectively. Four patients with gastrostomy and three controls did not complete the study (due to weaning from ventilatory support or death). After excluding these subjects, difference in VAP frequency persisted: two out of 16 subjects with gastrostomy had VAP (12.5%) versus eight out of 18 controls (44.4%). There were no differences in duration of hospitalisation or mortality between the two groups. In conclusion, in patients mechanically ventilated for stroke or head injury early gastrostomy is associated with a lower frequency of ventilator-associated pneumonia compared with a nasogastric tube. Copyright © ERS Journals Ltd 2005. | en |
dc.source | European Respiratory Journal | en |
dc.source.uri | http://www.scopus.com/inward/record.url?eid=2-s2.0-21744452169&partnerID=40&md5=4d6882d8669cf9bcacd2ca4ac00c974c | |
dc.subject | Mechanical ventilation | en |
dc.subject | Nosocomial pneumonia | en |
dc.subject | adult | en |
dc.subject | article | en |
dc.subject | artificial ventilation | en |
dc.subject | clinical article | en |
dc.subject | clinical protocol | en |
dc.subject | clinical trial | en |
dc.subject | controlled clinical trial | en |
dc.subject | controlled study | en |
dc.subject | disease severity | en |
dc.subject | enteric feeding | en |
dc.subject | female | en |
dc.subject | gastrostomy | en |
dc.subject | head injury | en |
dc.subject | human | en |
dc.subject | infection risk | en |
dc.subject | length of stay | en |
dc.subject | male | en |
dc.subject | mortality | en |
dc.subject | nasogastric tube | en |
dc.subject | priority journal | en |
dc.subject | randomized controlled trial | en |
dc.subject | risk factor | en |
dc.subject | risk reduction | en |
dc.subject | statistical analysis | en |
dc.subject | statistical significance | en |
dc.subject | stroke | en |
dc.subject | ventilator associated pneumonia | en |
dc.subject | Age Distribution | en |
dc.subject | APACHE | en |
dc.subject | Case-Control Studies | en |
dc.subject | Cerebrovascular Accident | en |
dc.subject | Chi-Square Distribution | en |
dc.subject | Cohort Studies | en |
dc.subject | Craniocerebral Trauma | en |
dc.subject | Critical Illness | en |
dc.subject | Cross Infection | en |
dc.subject | Glasgow Coma Scale | en |
dc.subject | Humans | en |
dc.subject | Incidence | en |
dc.subject | Injury Severity Score | en |
dc.subject | Middle Aged | en |
dc.subject | Pneumonia, Bacterial | en |
dc.subject | Probability | en |
dc.subject | Prognosis | en |
dc.subject | Reference Values | en |
dc.subject | Respiration, Artificial | en |
dc.subject | Risk Assessment | en |
dc.subject | Sex Distribution | en |
dc.subject | Time Factors | en |
dc.subject | Treatment Outcome | en |
dc.title | Early gastrostomy reduces the rate of ventilator-associated pneumonia in stroke or head injury patients | en |
dc.type | journalArticle | en |