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Morning levels of fibrinogen in children with sleep-disordered breathing
dc.creator | Kaditis, A. G. | en |
dc.creator | Alexopoulos, E. I. | en |
dc.creator | Kalampouka, E. | en |
dc.creator | Kostadima, E. | en |
dc.creator | Angelopoulos, N. | en |
dc.creator | Germenis, A. | en |
dc.creator | Zintzaras, E. | en |
dc.creator | Gourgoulianis, K. | en |
dc.date.accessioned | 2015-11-23T10:30:41Z | |
dc.date.available | 2015-11-23T10:30:41Z | |
dc.date.issued | 2004 | |
dc.identifier | 10.1183/09031936.04.00009804 | |
dc.identifier.issn | 0903-1936 | |
dc.identifier.uri | http://hdl.handle.net/11615/28680 | |
dc.description.abstract | Elevated fibrinogen level is a predictor of cardiovascular disease in adults, and it is associated with sleep-disordered breathing. Levels of fibrinogen in adults are affected by other co-existing cardiovascular risk factors, which are not usually present in children. To investigate the association between fibrinogen and sleep-disordered breathing, a case-control study was carried out in children with and without habitual snoring. All snoring children underwent polysomnography. Morning fibrinogen values in 30 children with snoring and an apnoea-hypopnoea index (AHI) greater than or equal to 5 episodes(.)h(-1) (median (interquartile range) 318 mg(.)dL(-1) (290-374)) were similar to values in 61 children with snoring and an AHI <5 episodes(.)h(-1) (307 (269-346)). Both groups had higher fibrinogen values than those in 23 controls without snoring (271 mg(.)dL(-1) (244-294)). There was no correlation between fibrinogen values and AHI, respiratory movement/arousal index or haemoglobin desaturation index. In conclusion, fibrinogen values are higher in children with snoring than in controls, but there is no association between these values and polysomnography indices. | en |
dc.source | European Respiratory Journal | en |
dc.source.uri | <Go to ISI>://WOS:000225009400017 | |
dc.subject | obstructive sleep apnoea | en |
dc.subject | polysomnography | en |
dc.subject | snoring | en |
dc.subject | POSITIVE AIRWAY PRESSURE | en |
dc.subject | INTERCELLULAR-ADHESION MOLECULE-1 | en |
dc.subject | C-REACTIVE | en |
dc.subject | PROTEIN | en |
dc.subject | APPARENTLY HEALTHY-MEN | en |
dc.subject | APNEA SYNDROME | en |
dc.subject | MYOCARDIAL-INFARCTION | en |
dc.subject | CARDIOVASCULAR RISK | en |
dc.subject | BLOOD-PRESSURE | en |
dc.subject | COR-PULMONALE | en |
dc.subject | HEART-DISEASE | en |
dc.subject | Respiratory System | en |
dc.title | Morning levels of fibrinogen in children with sleep-disordered breathing | en |
dc.type | journalArticle | en |
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