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Long-term prognostic value of Tc-99m tetrofosmin myocardial gated-SPECT imaging in asymptomatic patients after percutaneous coronary intervention
dc.creator | Georgoulias, P. | en |
dc.creator | Demakopoulos, N. | en |
dc.creator | Tzavara, C. | en |
dc.creator | Giannakou, S. | en |
dc.creator | Valotassiou, V. | en |
dc.creator | Tsougos, I. | en |
dc.creator | Xaplanteris, P. | en |
dc.creator | Fezoulidis, I. | en |
dc.date.accessioned | 2015-11-23T10:27:44Z | |
dc.date.available | 2015-11-23T10:27:44Z | |
dc.date.issued | 2008 | |
dc.identifier | 10.1097/RLU.0b013e318187ee88 | |
dc.identifier.issn | 3639762 | |
dc.identifier.uri | http://hdl.handle.net/11615/27785 | |
dc.description.abstract | PURPOSE: To evaluate the long-term prognostic value of Tc-99m tetrofosmin myocardial gated-SPECT in asymptomatic patients after coronary artery stenting. MATERIALS AND METHODS: We included 246 consecutive patients in the study. All patients underwent exercise gated-single photon emission computed tomography (SPECT) myocardial imaging 5 to 7 months after percutaneous coronary intervention (PCI) and were followed for a mean period of 8.3 years (SD = 2.9). Myocardial scintigrams were evaluated calculating the summed stress score (SSS), summed rest score, and summed difference score (SDS) indexes. Cardiovascular death and nonfatal myocardial infarction were considered hard cardiac events, whereas late revascularization (>3 months after myocardial SPECT) procedures were considered to be soft events. Cox proportional hazard models were applied to evaluate the association between several variables and the investigated outcome. RESULTS: During the follow-up period, hard cardiac events occurred in 32 (13%) patients (cardiac death occurred in 12 patients and nonfatal myocardial infarction in 20 patients). In addition, 60 (24.4%) patients underwent a late revascularization procedure. When multiple Cox regression analysis was implied, the factors that remained significant in the final model for soft events were SSS, SDS, and angina during exercise testing. In addition, SSS, SDS, and left ventricular dilatation were independently associated with hard cardiac events as defined from the results of multiple analysis. However, SSS and SDS were the only independent predictors for both hard and soft events. CONCLUSIONS: Tc-99m tetrofosmin myocardial perfusion imaging (MPI), performed 6 months post-percutaneous coronary intervention, has an independent and powerful clinical value to predict hard and soft cardiac events in asymptomatic patients after PCI. © 2008 by Lippincott Williams & Wilkins. | en |
dc.source | Clinical Nuclear Medicine | en |
dc.source.uri | http://www.scopus.com/inward/record.url?eid=2-s2.0-58149237878&partnerID=40&md5=95d90287fe127a84bef6be0755e60ece | |
dc.subject | Long-term prognosis | en |
dc.subject | Myocardial SPECT | en |
dc.subject | PCI | en |
dc.subject | Tc-99m tetrofosmin | en |
dc.subject | tetrofosmin tc 99m | en |
dc.subject | organophosphorus compound | en |
dc.subject | radiopharmaceutical agent | en |
dc.subject | technetium complex | en |
dc.subject | technetium Tc 99m 1,2 bis(bis(2 ethoxyethyl)phosphino)ethane | en |
dc.subject | technetium Tc 99m 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane | en |
dc.subject | unclassified drug | en |
dc.subject | adult | en |
dc.subject | aged | en |
dc.subject | analytic method | en |
dc.subject | angina pectoris | en |
dc.subject | article | en |
dc.subject | clinical evaluation | en |
dc.subject | coronary stent | en |
dc.subject | dilatation | en |
dc.subject | disease association | en |
dc.subject | exercise | en |
dc.subject | exercise test | en |
dc.subject | female | en |
dc.subject | follow up | en |
dc.subject | gated imaging | en |
dc.subject | heart death | en |
dc.subject | heart infarction | en |
dc.subject | heart left ventricle | en |
dc.subject | heart muscle perfusion | en |
dc.subject | human | en |
dc.subject | major clinical study | en |
dc.subject | male | en |
dc.subject | outcome assessment | en |
dc.subject | percutaneous coronary intervention | en |
dc.subject | photon emission tomography | en |
dc.subject | predictor variable | en |
dc.subject | prognosis | en |
dc.subject | proportional hazards model | en |
dc.subject | regression analysis | en |
dc.subject | revascularization | en |
dc.subject | scintigraphy | en |
dc.subject | single photon emission computer tomography | en |
dc.subject | summed difference score | en |
dc.subject | summed rest score | en |
dc.subject | summed stress score | en |
dc.subject | coronary artery blood flow | en |
dc.subject | coronary artery disease | en |
dc.subject | coronary blood vessel | en |
dc.subject | heart | en |
dc.subject | methodology | en |
dc.subject | middle aged | en |
dc.subject | mortality | en |
dc.subject | pathophysiology | en |
dc.subject | restenosis | en |
dc.subject | scintiscanning | en |
dc.subject | transluminal coronary angioplasty | en |
dc.subject | Angioplasty, Transluminal, Percutaneous Coronary | en |
dc.subject | Coronary Circulation | en |
dc.subject | Coronary Restenosis | en |
dc.subject | Coronary Vessels | en |
dc.subject | Gated Blood-Pool Imaging | en |
dc.subject | Humans | en |
dc.subject | Myocardial Infarction | en |
dc.subject | Organophosphorus Compounds | en |
dc.subject | Organotechnetium Compounds | en |
dc.subject | Radiopharmaceuticals | en |
dc.subject | Tomography, Emission-Computed, Single-Photon | en |
dc.title | Long-term prognostic value of Tc-99m tetrofosmin myocardial gated-SPECT imaging in asymptomatic patients after percutaneous coronary intervention | en |
dc.type | journalArticle | en |
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