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Respiratory and Immune Response to Maximal Physical Exertion following Exposure to Secondhand Smoke in Healthy Adults
dc.creator | Flouris, A. D. | en |
dc.creator | Metsios, G. S. | en |
dc.creator | Carrill, A. E. | en |
dc.creator | Jamurtas, A. Z. | en |
dc.creator | Stivaktakis, P. D. | en |
dc.creator | Tzatzarakis, M. N. | en |
dc.creator | Tsatsakis, A. M. | en |
dc.creator | Koutedakis, Y. | en |
dc.date.accessioned | 2015-11-23T10:26:36Z | |
dc.date.available | 2015-11-23T10:26:36Z | |
dc.date.issued | 2012 | |
dc.identifier | 10.1371/journal.pone.0031880 | |
dc.identifier.issn | 1932-6203 | |
dc.identifier.uri | http://hdl.handle.net/11615/27491 | |
dc.description.abstract | We assessed the cardiorespiratory and immune response to physical exertion following secondhand smoke (SHS) exposure through a randomized crossover experiment. Data were obtained from 16 (8 women) non-smoking adults during and following a maximal oxygen uptake cycling protocol administered at baseline and at 0-, 1-, and 3-hours following 1-hour of SHS set at bar/restaurant carbon monoxide levels. We found that SHS was associated with a 12% decrease in maximum power output, an 8.2% reduction in maximal oxygen consumption, a 6% increase in perceived exertion, and a 6.7% decrease in time to exhaustion (P<0.05). Moreover, at 0-hours almost all respiratory and immune variables measured were adversely affected (P<0.05). For instance, FEV1 values at 0-hours dropped by 17.4%, while TNF-alpha increased by 90.1% (P<0.05). At 3-hours mean values of cotinine, perceived exertion and recovery systolic blood pressure in both sexes, IL4, TNF-alpha and IFN-gamma in men, as well as FEV1/FVC, percent predicted FEV1, respiratory rate, and tidal volume in women remained different compared to baseline (P<0.05). It is concluded that a 1-hour of SHS at bar/restaurant levels adversely affects the cardiorespiratory and immune response to maximal physical exertion in healthy nonsmokers for at least three hours following SHS. | en |
dc.source | Plos One | en |
dc.source.uri | <Go to ISI>://WOS:000302741300101 | |
dc.subject | THYROID-HORMONE SECRETION | en |
dc.subject | PASSIVE SMOKING | en |
dc.subject | TOBACCO-SMOKE | en |
dc.subject | CIGARETTE-SMOKING | en |
dc.subject | CARBON-MONOXIDE | en |
dc.subject | LUNG-FUNCTION | en |
dc.subject | YOUNG ADULTS | en |
dc.subject | PREVALENCE | en |
dc.subject | OCCUPATION | en |
dc.subject | RISK | en |
dc.subject | Multidisciplinary Sciences | en |
dc.title | Respiratory and Immune Response to Maximal Physical Exertion following Exposure to Secondhand Smoke in Healthy Adults | en |
dc.type | journalArticle | en |
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