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“Blame it on the Comorbidities”: A 5-Year Follow-Up of 53 Chronic Dialysis-Dependent Patients Who Underwent Cardiac Surgery
dc.creator | Deutsch, O. | en |
dc.creator | Rippinger, N. | en |
dc.creator | Spiliopoulos, K. | en |
dc.creator | Eichinger, W. | en |
dc.creator | Gansera, B. | en |
dc.date.accessioned | 2015-11-23T10:25:23Z | |
dc.date.available | 2015-11-23T10:25:23Z | |
dc.date.issued | 2014 | |
dc.identifier | 10.1055/s-0034-1543979 | |
dc.identifier.issn | 1716425 | |
dc.identifier.uri | http://hdl.handle.net/11615/27010 | |
dc.description.abstract | Objectives This study evaluates midterm survival rates and risk factors for mortality of chronic dialysis-dependent patients undergoing cardiac surgery. Methods Fifty-three dialysis-dependent patients (34 males, aged 67 ± 12 years) with end-stage renal disease operated within March 2007 and May 2012 were analyzed retrospectively. Survival rates were calculated using Kaplan–Meier methods. Predictors of midterm survival were identified with multivariate Cox-regression analysis. Results Twenty-three patients received isolated coronary artery bypass graft surgery, 17 received isolated valve replacement, and 13 received combined procedures. Thirty-day mortality was 24.5% (n = 13). Follow-up was complete for 94.3% (n = 50). Survival rates at 1, 3, and 5 years were: 82, 50, and 17%, respectively. Neither age, gender, poor ejection fraction, emergency, ECC/X-clamp (cross-clamp) time, nor use of left internal thoracic artery or right internal thoracic artery had any influence on midterm survival. Causes of death within midterm follow-up period were related to cardiac events in 16% and neurological events in 16%. In the majority (47%), cause of death was associated with peripheral arterial disease (PAD). The only comorbidity, which could be identified as a significant risk factor, was PAD (p = 0.035). Five patients underwent successful renal transplantation within the follow-up period. Conclusion Although 30-day mortality in this high-risk patient population was increased, midterm survival rates were comparable to the results described in the literature. Cause of death within midterm follow-up period was mostly noncardiac related. Given the limited number of patients, predictors for enhanced 30-day mortality, such as preoperative myocardial infarction, prolonged extracorporeal circulation, operation time, and diabetes mellitus, did not have an influence on midterm survival. Copyright © 2014, Georg Thieme Verlag KG. All rights reserved. | en |
dc.source.uri | http://www.scopus.com/inward/record.url?eid=2-s2.0-84925422859&partnerID=40&md5=ee448c5e7b3796ae12d098435662e434 | |
dc.subject | cardiac | en |
dc.subject | kidney | en |
dc.subject | peripheral vascular disease | en |
dc.title | “Blame it on the Comorbidities”: A 5-Year Follow-Up of 53 Chronic Dialysis-Dependent Patients Who Underwent Cardiac Surgery | en |
dc.type | journalArticle | en |
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