Genetic susceptibility to primary intracerebral haemorrhage

dc.creator	Dardiotis, E.	en
dc.creator	Dardioti, M.	en
dc.creator	Xiromerisiou, G.	en
dc.creator	Paterakis, K.	en
dc.creator	Fountas, K.	en
dc.creator	Hadjigeorgiou, G. M.	en
dc.date.accessioned	2015-11-23T10:25:12Z
dc.date.available	2015-11-23T10:25:12Z
dc.date.issued	2009
dc.identifier.issn	17583837
dc.identifier.uri	http://hdl.handle.net/11615/26924
dc.description.abstract	Primary intracerebral haemorrhage (PICH) originates from the spontaneous rupture of cerebral arteries as a result of chronic degenerative alterations. Although the aetiology of PICH has not been fully elucidated, it may be the result of an interaction between genetic and environmental risk factors. Several genetic association studies have been conducted in patients with PICH with both positive and negative results. Most of them investigated the role of mutations in genes affecting the lipid metabolism, the coagulation processes, the inflammation and the regulation of blood pressure. In this article we briefly discuss the majority of these studies reporting the susceptibility genes that have been implicated in PICH. © 2012 Touch Group PLC.	en
dc.source.uri	http://www.scopus.com/inward/record.url?eid=2-s2.0-79951681323&partnerID=40&md5=4bc1f54427acd7e069e3c2f5394dac64
dc.subject	Association studies	en
dc.subject	Genetics	en
dc.subject	Polymorphism	en
dc.subject	Primary intracranial haemorrhage (PICH)	en
dc.title	Genetic susceptibility to primary intracerebral haemorrhage	en
dc.type	journalArticle	en

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