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Prognostic value of follicular fluid 25-OH vitamin D and glucose levels in the IVF outcome
dc.creator | Anifandis, G. M. | en |
dc.creator | Dafopoulos, K. | en |
dc.creator | Messini, C. I. | en |
dc.creator | Chalvatzas, N. | en |
dc.creator | Liakos, N. | en |
dc.creator | Pournaras, S. | en |
dc.creator | Messinis, I. E. | en |
dc.date.accessioned | 2015-11-23T10:22:28Z | |
dc.date.available | 2015-11-23T10:22:28Z | |
dc.date.issued | 2010 | |
dc.identifier | 10.1186/1477-7827-8-91 | |
dc.identifier.issn | 1477-7827 | |
dc.identifier.uri | http://hdl.handle.net/11615/25651 | |
dc.description.abstract | Objectives: The aim of the present study was to measure serum and follicular fluid 25-OH vitamin D and glucose levels in women who underwent IVF-ET treatment and to further investigate whether the circulating 25-OH vitamin D and glucose levels correlate with IVF success. Methods: This prospective observational study included 101 consecutive women who underwent 101 IVF-ICSI ovarian stimulation cycles and were allocated to one of the three groups according to their follicular fluid 25-OH vitamin D concentrations. Group A (n = 31) with less than 20 ng/ml, group B (n = 49) with vitamin levels between 20.1 and 30 ng/ml and group C (n = 21) with more than 30 ng/ml vitamin concentration. Results: Follicular fluid vitamin levels significantly correlated with the quality of embryos in total (r = -0.27, p = 0.027), while the quality of embryos of group C were of lower quality as compared to those of groups A and B (p = 0.009). Follicular fluid glucose levels were lower in women of group C as compared to the respective levels of groups A and B (p = 0.003). Clinical pregnancy rate demonstrated in 14.5% in women of group C and 32.3% and 32.7% in groups A and B, respectively (p = 0.047). Conclusion: The data suggests that excess serum and follicular fluid vitamin levels in combination with decreased follicular fluid glucose levels have a detrimental impact on the IVF outcome. | en |
dc.source | Reproductive Biology and Endocrinology | en |
dc.source.uri | <Go to ISI>://WOS:000282555600001 | |
dc.subject | IN-VITRO MATURATION | en |
dc.subject | DEFICIENCY | en |
dc.subject | PREGNANCY | en |
dc.subject | OOCYTES | en |
dc.subject | BOVINE | en |
dc.subject | RISK | en |
dc.subject | Endocrinology & Metabolism | en |
dc.subject | Reproductive Biology | en |
dc.title | Prognostic value of follicular fluid 25-OH vitamin D and glucose levels in the IVF outcome | en |
dc.type | journalArticle | en |
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