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Large Dissemination of VIM-2-Metallo-beta-Lactamase-Producing Pseudomonas aeruginosa Strains Causing Health Care-Associated Community-Onset Infections
(2009)
During a 3-year period (May 2005 to April 2008), a series of 45 outpatients presented with community-onset urinary tract infections due to carbapenem-resistant Pseudomonas aeruginosa isolates. Forty of them had a history ...
Clusters of imipenem-resistant Acinetobacter baumannii clones producing different carbapenemases in an intensive care unit
(2008)
During a 2-year period (April 2005-March 2007), 31 intensive care unit (ICU) patients in a Greek hospital were infected or colonised with imipenem-resistant isolates of Acinetobacter baumannii. Twelve patients died, with ...
Transmission in the community of clonal Proteus mirabilis carrying VIM-1 metallo-beta-lactamase
(2007)
Objectives: Several infections among patients attending our outpatient clinic were caused by imipenem-resistant Proteus mirabilis that were phenotypically metallo-beta-lactamase (MBL)-positive. The aim of the study was to ...
Increasing prevalence of high-level gentamicin resistance among enterococci isolated in Greece
(2001)
High-level gentamicin-resistant enterococci (HLGRE) (MIC >512 mug/ml) were frequently recovered in the AHEPA University Hospital, Thessaloniki, Greece, during a 15-month period (67/158, 42.4%). PCR testing showed that ...
Molecular cloning and biochemical characterization of VIM-12, a novel hybrid VIM-1/VIM-2 metallo-beta-lactamase from a Klebsiella pneumoniae clinical isolate, reveal atypical substrate specificity
(2007)
Metallo-beta-lactamases (MBLs) are considered an emerging family of Zn2+-dependent enzymes that significantly contribute to the resistance of many nosocomial pathogens against beta-lactam antimicrobials. Since these ...
Hidden VIM-1 metallo-beta-lactamase phenotypes among Acinetobacter baumannii clinical isolates
(2008)
A total of 87 Acinetobacter baumannii nonrepetitive consecutive clinical isolates were tested for the presence of metallo-beta-lactamases (MBLs). Results of phenotypic assays (MBL Etest, imipenem/imipenem-EDTA combined-disk ...
A highly carbapenem-resistant Pseudomonas aeruginosa isolate with a novel bla(VIM-4)/bla(P1b) integron overexpresses two efflux pumps and lacks OprD
(2007)
Objectives: A Pseudomonas aeruginosa clinical isolate that exhibited high-level carbapenem resistance and produced metallo-beta-lactamase (MBL) was recovered from a Greek patient. This study was conducted to determine the ...
Emergence of carbapenem-resistant enterobacter cloacae carrying VIM-4 metallo-beta-lactamase and SHV-2a extended-spectrum beta-lactamase in a conjugative plasmid
(2007)
Enterobacter cloacae strains are still infrequently resistant to carbapenems. A carbapenem-resistant clinical isolate of E. cloacae producing a plasmid-mediated metallo-beta-lactamase (MBL), VIM-4, was recovered from a ...
Heteroresistance to Meropenem in Carbapenem-Susceptible Acinetobacter baumannii
(2009)
The characteristics of carbapenem heteroresistance were studied in 14 apparently carbapenem-susceptible Acinetobacter baumannii isolates. The MICs for carbapenems were determined, and the isolates were genotyped by ...
Outbreak caused by a multidrug-resistant Klebsiella pneumoniae clone carrying bla(VIM-12) in a university hospital
(2008)
From November 2006 to April 2007, nine nonrepetitive isolates of Klebsiella pneumoniae with reduced susceptibility or resistance to carbapenems were recovered from clinical specimens from separate patients hospitalized in ...