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Involvement of SOX-9 and FGF-23 in RUNX-2 regulation in osteoarthritic chondrocytes
(2009)
Chondrocytes' hypertrophy includes metabolic changes, matrix remodelling, proliferation and apoptosis, characteristics associated with the progression of osteoarthritis. We investigated a possible association among ...
Use of real-time PCR to detect human papillomavirus-16 viral loads in vaginal and urine self-sampled specimens
(2008)
Increasing the accuracy of self-sampling methods to detect oncogenic human papillomavirus (HPV) infection would contribute to the wider application of these approaches. In this study, 120 women were tested for HPV-16 by ...
Real-time quantification of human telomerase reverse transcriptase mRNA in liver tissues from patients with hepatocellular cancer and chronic viral hepatitis
(2007)
We determined, for the first time, the human telomerase reverse transcriptase (hTERT) mRNA expression, using real-time quantitative PCR, in liver tissues from patients with hepatocellular cancer (HCC; n = 13), chronic ...
Correlation of promoter hypermethylation in hTERT, DAPK and MGMT genes with cervical oncogenesis progression
(2009)
DNA hypermethylation occurs during the multi-step process of cervical carcinogenesis. We investigated whether the methylation status in the promoter region of a potential oncogene, the human telomerase reverse transcriptase ...
Interleukin-10G and interleukin-10R microsatellite polymorphisms and osteoarthritis of the knee
(2005)
Objective To clarify and evaluate the possible role of interleukin-10G (IL-10G) and interleukin-10R (IL-10R) microsatellite polymorphisms of IL-10 gene in knee osteoarthritis (OA). Methods This was a case-control study. ...
UGT1A1 promoter polymorphism as a predisposing factor of hyperbilirubinaemia in neonates with acute pyelonephritis
(2006)
We describe 4 jaundiced neonates with acute pyelonephritis of whom family history was positive for or pointed to Gilbert's syndrome (GS). Uridine diphosphate glucuronosyltransferase 1A1 (UGT-1A1), ( TA) 7 polymorphism, ...