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VEGF increases the permeability of sheep pleura ex vivo through VEGFR2 stimulation
(2014)
Vascular endothelial growth factor (VEGF), a cytokine that increases vascular permeability to water and proteins and induces angiogenesis, has been implicated in the development of pleural effusions. Inflammatory and ...
TNF alpha induces expression of HIF-1 mRNA and protein but inhibits hypoxic stimulation of HIF-1 alpha transcriptional activity in airway smooth muscle cells
(2013)
Airway smooth muscle cells (ASMCs) participate in tissue remodeling characteristic of airway inflammatory diseases like asthma. Inflammation and hypoxia pathways are often interconnected and the regulatory subunit of the ...
Role of Histamine in Altering Fluid Recycling in Normal and Post-Traumatic Rabbit Peritoneum
(2014)
This study aims to investigate if histamine induces electrochemical alterations in the normal and post-traumatic peritoneum. Peritoneal rabbit specimens were obtained before surgery and 10 days post-operatively and were ...
IGF-1 alters the human parietal pleural electrochemical profile by inhibiting ion trans-cellular transportation after interaction with its receptor
(2013)
Objective: The effect of IGF-1 in the human pleural permeability and the underlying mechanisms involved were investigated. Design: Specimens from thoracic surgical patients were mounted in Ussing chambers. Solutions ...
Effect of histamine on the electrophysiology of the human parietal pleura
(2011)
Introduction: Histamine is involved in the pathogenesis of numerous diseases and regulates the permeability of different tissues. The aim of this study is to investigate the effects of histamine on the electrophysiology ...